Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR159W
Length:
347
Number of sequences:
5887
Description:
YBR159W IFA38 SGDID:S000000363, Chr II from 558685-559728, Genome Release 64-1-1, Verified ORF, "Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31A6RBW9    339   MKAR_AJECN 3-ketoacyl-CoA reductase OS=(Histo...3102e-90     281     46     65GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
32Q10245    341   MKAR_SCHPO 3-ketoacyl-CoA reductase OS=Schizo...3041e-81     258     46     62GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045703; F:ketoreductase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0030497; P:fatty acid elongation; ISS:PomBase.
33A8N6B4    339   MKAR_COPC7 3-ketoacyl-CoA reductase OS=9003) ...3552e-81     258     40     59GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
34B0D8R3    338   MKAR_LACBS 3-ketoacyl-CoA reductase OS=deceiv...3085e-77     246     40     63GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
35Q4P622    350   MKAR_USTMA 3-ketoacyl-CoA reductase OS=Ustila...3265e-74     239     41     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
36P0CR34    361   MKAR_CRYNJ 3-ketoacyl-CoA reductase OS=ATCC M...3206e-73     236     42     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
37P0CR35    361   MKAR_CRYNB 3-ketoacyl-CoA reductase OS=(Filob...3206e-73     236     42     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
38A8Q1U2    324   MKAR_MALGO 3-ketoacyl-CoA reductase OS=(Dandr...3344e-71     230     39     59GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
39Q28IU1    320   DHB12_XENTR Estradiol 17-beta-dehydrogenase 1...3221e-44     161     33     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
40Q53GQ0    312   DHB12_HUMAN Estradiol 17-beta-dehydrogenase 1...3286e-44     159     32     53GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
41Q4R5G7    312   DHB12_MACFA Estradiol 17-beta-dehydrogenase 1...3282e-43     157     32     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
42Q5E9H7    312   DHB12_BOVIN Estradiol 17-beta-dehydrogenase 1...3194e-43     157     30     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
43O57314    312   DHB12_ANAPL Estradiol 17-beta-dehydrogenase 1...3347e-43     156     33     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
44Q6P7R8    312   DHB12_RAT Estradiol 17-beta-dehydrogenase 12 ...3328e-43     156     32     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
45Q6P3L6    319   DH12A_DANRE Estradiol 17-beta-dehydrogenase 1...2612e-42     155     34     57GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
46O70503    312   DHB12_MOUSE Estradiol 17-beta-dehydrogenase 1...3255e-42     154     33     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031012; C:extracellular matrix; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005518; F:collagen binding; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0001968; F:fibronectin binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0030198; P:extracellular matrix organization; IDA:MGI.::GO:0010811; P:positive regulation of cell-substrate adhesion; IDA:MGI.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
47Q8AVY8    318   DH12B_XENLA Estradiol 17-beta-dehydrogenase 1...2857e-42     154     34     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
48Q5XG41    318   DH12A_XENLA Estradiol 17-beta-dehydrogenase 1...2845e-41     151     33     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
49Q6QA33    311   DH12B_DANRE Estradiol 17-beta-dehydrogenase 1...2802e-40     149     35     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
50Q3SXM5    330   HSDL1_HUMAN Inactive hydroxysteroid dehydroge...2571e-36     140     32     54GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
51P37058    310   DHB3_HUMAN Testosterone 17-beta-dehydrogenase...2502e-36     139     36     56GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; TAS:ProtInc.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.
GO:0006702; P:androgen biosynthetic process; TAS:Reactome.::GO:0030539; P:male genitalia development; TAS:ProtInc.
52Q5R7K0    330   HSDL1_PONAB Inactive hydroxysteroid dehydroge...2572e-36     139     32     54GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
53A5PJF6    330   HSDL1_BOVIN Inactive hydroxysteroid dehydroge...2888e-36     137     30     53GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
54Q4V8B7    330   HSDL1_RAT Inactive hydroxysteroid dehydrogena...2596e-35     135     32     54GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
55Q5ZJG8    331   HSDL1_CHICK Hydroxysteroid dehydrogenase-like...2904e-34     133     30     52GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
56Q8BTX9    330   HSDL1_MOUSE Inactive hydroxysteroid dehydroge...2595e-34     132     32     53GO:0005739; C:mitochondrion; IDA:MGI.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
57Q09517    316   LE767_CAEEL Putative steroid dehydrogenase le...3295e-34     132     30     49GO:0045179; C:apical cortex; IDA:WormBase.::GO:0005783; C:endoplasmic reticulum; IDA:WormBase.
GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; IDA:WormBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0008209; P:androgen metabolic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008210; P:estrogen metabolic process; IMP:WormBase.::GO:0030540; P:female genitalia development; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0042759; P:long-chain fatty acid biosynthetic process; IDA:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0032350; P:regulation of hormone metabolic process; IMP:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IDA:WormBase.
58Q60V51    316   LE767_CAEBR Putative steroid dehydrogenase le...3294e-33     130     30     49
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0030540; P:female genitalia development; ISS:UniProtKB.::GO:0042303; P:molting cycle; ISS:UniProtKB.::GO:0032350; P:regulation of hormone metabolic process; ISS:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
59O54939    306   DHB3_RAT Testosterone 17-beta-dehydrogenase 3...2822e-30     122     34     53GO:0005792; C:microsome; IDA:RGD.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.
GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071371; P:cellular response to gonadotropin stimulus; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0017143; P:insecticide metabolic process; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0006082; P:organic acid metabolic process; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0033591; P:response to L-ascorbic acid; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0006694; P:steroid biosynthetic process; IDA:RGD.
60P70385    305   DHB3_MOUSE Testosterone 17-beta-dehydrogenase...2761e-29     120     33     53
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
61O17795    315   STDH2_CAEEL Putative steroid dehydrogenase 2 ...2732e-28     116     28     48
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
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