UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR159W

Length:

347

Number of sequences:

5887

Description:

YBR159W IFA38 SGDID:S000000363, Chr II from 558685-559728, Genome Release 64-1-1, Verified ORF, "Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
241	Q6AYS8	298	DHB11_RAT Estradiol 17-beta-dehydrogenase 11 ...	185	0.000009	50.4	25	46	GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
242	P71079	250	FABL_BACSU Enoyl-[acyl-carrier-protein] reduc...	193	0.000009	50.1	31	47
									GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IDA:UniProtKB.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0050661; F:NADP binding; IDA:UniProtKB.
									GO:0030497; P:fatty acid elongation; IDA:UniProtKB.]::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.]
243	P80873	286	GS39_BACSU General stress protein 39 OS=Bacil...	208	0.000009	50.1	23	45
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.
244	Q920P0	244	DCXR_RAT L-xylulose reductase OS=Rattus norve...	201	0.00001	49.7	24	44	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB.
245	A4IFM3	313	DR9C7_BOVIN Short-chain dehydrogenase/reducta...	192	0.00001	50.1	25	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
246	P50164	260	TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamu...	228	0.00001	49.7	24	44
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050358; F:tropinone reductase activity; IEA:EC.
247	Q9EQ06	298	DHB11_MOUSE Estradiol 17-beta-dehydrogenase 1...	185	0.00001	49.7	26	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
248	P51976	406	DHI2_RABIT Corticosteroid 11-beta-dehydrogena...	188	0.00001	50.1	28	45	GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
249	P51975	292	DHI1_SHEEP Corticosteroid 11-beta-dehydrogena...	199	0.00001	49.7	25	45	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
250	C1C4R8	245	BDH2_LITCT 3-hydroxybutyrate dehydrogenase ty...	256	0.00002	49.3	25	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
									GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; ISS:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; ISS:UniProtKB.
251	Q9P324	236	YI78_SCHPO Uncharacterized oxidoreductase C97...	111	0.00002	48.9	30	49	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:PomBase.
252	Q4L8Y1	231	Y0585_STAHJ Uncharacterized oxidoreductase SH...	202	0.00002	48.9	26	43
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
253	Q6PUF3	287	DHI1L_DANRE Hydroxysteroid 11-beta-dehydrogen...	240	0.00002	49.3	23	42	GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016229; F:steroid dehydrogenase activity; ISS:ZFIN.
254	P50170	317	RDH2_RAT Retinol dehydrogenase 2 OS=Rattus no...	190	0.00002	49.3	25	45	GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:RGD.
									GO:0042573; P:retinoic acid metabolic process; IDA:RGD.::GO:0042572; P:retinol metabolic process; IDA:RGD.
255	P23170	258	25KD_SARPE Development-specific 25 kDa protei...	173	0.00002	49.3	24	46
									GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
256	Q949M2	254	FABG4_BRANA 3-oxoacyl-[acyl-carrier-protein] ...	198	0.00002	49.3	25	48	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
257	P70684	265	PGDH_CAVPO 15-hydroxyprostaglandin dehydrogen...	220	0.00002	49.3	24	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB.
									GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
258	P40471	297	AYR1_YEAST NADPH-dependent 1-acyldihydroxyace...	186	0.00002	49.3	24	46	GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005811; C:lipid particle; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
									GO:0000140; F:acylglycerone-phosphate reductase activity; IMP:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006654; P:phosphatidic acid biosynthetic process; IMP:SGD.
259	P15428	266	PGDH_HUMAN 15-hydroxyprostaglandin dehydrogen...	208	0.00002	48.9	24	44	GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
									GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IDA:UniProtKB.::GO:0019372; P:lipoxygenase pathway; TAS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
260	P50233	400	DHI2_RAT Corticosteroid 11-beta-dehydrogenase...	193	0.00003	49.3	27	44	GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.
									GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD.
									GO:0007565; P:female pregnancy; IEP:RGD.::GO:0008211; P:glucocorticoid metabolic process; IDA:RGD.::GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032094; P:response to food; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.]
261	Q9NZC7	414	WWOX_HUMAN WW domain-containing oxidoreductas...	165	0.00003	49.3	26	46	GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
									GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
262	P70720	242	FABG_AGGAC 3-oxoacyl-[acyl-carrier-protein] r...	195	0.00003	48.5	27	49
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
263	Q8MJY8	266	PGDH_MACFA 15-hydroxyprostaglandin dehydrogen...	208	0.00003	48.5	24	44	GO:0005737; C:cytoplasm; IDA:UniProtKB.
									GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB.
									GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; IEP:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
264	P28643	320	FABG_CUPLA 3-oxoacyl-[acyl-carrier-protein] r...	198	0.00003	48.9	26	47	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
265	Q6PUF4	287	DHI1L_CHICK Hydroxysteroid 11-beta-dehydrogen...	199	0.00003	48.5	24	44	GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
266	Q9BPW9	319	DHRS9_HUMAN Dehydrogenase/reductase SDR famil...	202	0.00004	48.5	24	47	GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IDA:UniProtKB.
									GO:0004022; F:alcohol dehydrogenase (NAD) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016854; F:racemase and epimerase activity; NAS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:UniProtKB.
									GO:0042904; P:9-cis-retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0030855; P:epithelial cell differentiation; NAS:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0042572; P:retinol metabolic process; NAS:UniProtKB.
267	Q8BYK4	316	RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus m...	89	0.00004	48.5	33	55	GO:0005622; C:intracellular; ISS:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.
									GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
268	P00335	249	RIDH_ENTAE Ribitol 2-dehydrogenase OS=Enterob...	202	0.00004	48.1	25	45
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050255; F:ribitol 2-dehydrogenase activity; IEA:EC.
269	Q05528	253	KDUD_DICD3 2-dehydro-3-deoxy-D-gluconate 5-de...	209	0.00004	48.1	25	46
									GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
270	Q73SC8	275	Y4146_MYCPA Uncharacterized NAD-dependent oxi...	224	0.00004	48.1	25	43
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
271	Q5R9W5	414	WWOX_PONAB WW domain-containing oxidoreductas...	165	0.00004	48.5	26	46	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.

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