rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q5REQ0 | 323 | AK1C1_PONAB Aldo-keto reductase family 1 memb... | 303 | 2e-43 | 158 | 36 | 55 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 62 | P16116 | 315 | ALDR_BOVIN Aldose reductase OS=Bos taurus (Bo... | 292 | 2e-43 | 157 | 38 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 63 | Q95JH7 | 323 | AK1C1_MACFA Aldo-keto reductase family 1 memb... | 301 | 4e-43 | 157 | 36 | 56 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 64 | Q8VC28 | 323 | AK1CD_MOUSE Aldo-keto reductase family 1 memb... | 322 | 5e-43 | 157 | 33 | 56 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006805; P:xenobiotic metabolic process; TAS:MGI. | 65 | O34678 | 280 | YTBE_BACSU Uncharacterized oxidoreductase Ytb... | 297 | 5e-43 | 155 | 36 | 53 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 66 | P31210 | 326 | AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenas... | 330 | 5e-43 | 157 | 33 | 53 | | | | | | | | | | | GO:0047568; F:3-oxo-5-beta-steroid 4-dehydrogenase activity; IDA:MGI.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 67 | Q6GMC7 | 327 | AK1A1_XENLA Alcohol dehydrogenase [NADP(+)] O... | 339 | 8e-43 | 156 | 34 | 55 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 68 | P80276 | 316 | ALDR_PIG Aldose reductase OS=Sus scrofa (Pig)... | 287 | 9e-43 | 156 | 38 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 69 | Q5ZK84 | 327 | AK1A1_CHICK Alcohol dehydrogenase [NADP(+)] O... | 328 | 1e-42 | 156 | 35 | 55 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 70 | P15122 | 316 | ALDR_RABIT Aldose reductase OS=Oryctolagus cu... | 286 | 1e-42 | 155 | 36 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 71 | Q6Y0Z3 | 324 | XYL1_CANPA NADH-dependent D-xylose reductase ... | 311 | 2e-42 | 155 | 34 | 53 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 72 | P15121 | 316 | ALDR_HUMAN Aldose reductase OS=Homo sapiens (... | 284 | 4e-42 | 154 | 38 | 60 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0043795; F:glyceraldehyde oxidoreductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006700; P:C21-steroid hormone biosynthetic process; TAS:Reactome.::GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.::GO:0006950; P:response to stress; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 73 | P42330 | 323 | AK1C3_HUMAN Aldo-keto reductase family 1 memb... | 300 | 5e-42 | 154 | 35 | 55 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IDA:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; IDA:UniProtKB.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; IDA:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IEP:UniProtKB.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0044259; P:multicellular organismal macromolecule metabolic process; IEP:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; IMP:UniProtKB.::GO:0070293; P:renal absorption; NAS:UniProtKB.::GO:0007584; P:response to nutrient; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; IMP:UniProtKB. | 74 | Q5RJP0 | 316 | ALD1_RAT Aldose reductase-related protein 1 O... | 286 | 1e-41 | 153 | 35 | 57 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:RGD. | | | | | | | | | | | 75 | P23901 | 320 | ALDR_HORVU Aldose reductase OS=Hordeum vulgar... | 282 | 2e-41 | 152 | 36 | 55 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 76 | Q5R7C9 | 323 | AK1C3_PONAB Aldo-keto reductase family 1 memb... | 300 | 2e-41 | 152 | 34 | 55 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; ISS:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; ISS:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; ISS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ISS:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; ISS:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; ISS:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; ISS:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; ISS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; ISS:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; ISS:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; ISS:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; ISS:UniProtKB.::GO:0016488; P:farnesol catabolic process; ISS:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.::GO:0042448; P:progesterone metabolic process; ISS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; ISS:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; ISS:UniProtKB.::GO:0042574; P:retinal metabolic process; ISS:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; ISS:UniProtKB. | 77 | P26690 | 315 | 6DCS_SOYBN NAD(P)H-dependent 6'-deoxychalcone... | 276 | 8e-41 | 150 | 35 | 58 | | | | | | | | | | | GO:0033808; F:6'-deoxychalcone synthase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 78 | P38715 | 327 | GRE3_YEAST NADPH-dependent aldose reductase G... | 320 | 1e-40 | 150 | 31 | 54 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0032866; F:D-xylose:NADP reductase activity; IDA:SGD.::GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; IDA:SGD.::GO:0003729; F:mRNA binding; IDA:SGD. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; IMP:SGD.::GO:0042843; P:D-xylose catabolic process; IDA:SGD.::GO:0006950; P:response to stress; IDA:SGD. | 79 | Q28FD1 | 327 | AK1A1_XENTR Alcohol dehydrogenase [NADP(+)] O... | 335 | 1e-40 | 150 | 34 | 54 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 80 | A1UEC5 | 283 | Y1984_MYCSK Uncharacterized oxidoreductase Mk... | 303 | 4e-40 | 148 | 36 | 50 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 81 | Q1BAN7 | 283 | Y1938_MYCSS Uncharacterized oxidoreductase Mm... | 303 | 4e-40 | 148 | 36 | 50 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 82 | O32210 | 276 | GR_BACSU Glyoxal reductase OS=Bacillus subtil... | 293 | 7e-40 | 147 | 37 | 53 | | | | | | | | | | | GO:0043892; F:methylglyoxal reductase (NADPH-dependent) activity; IEA:EC. | | | | | | | | | | | 83 | P78736 | 318 | XYL1_PACTA NAD(P)H-dependent D-xylose reducta... | 306 | 8e-40 | 148 | 34 | 53 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 84 | Q9P430 | 323 | XYL1_CANSH NAD(P)H-dependent D-xylose reducta... | 311 | 9e-40 | 148 | 33 | 52 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 85 | P51652 | 323 | AKC1H_RAT Aldo-keto reductase family 1 member... | 302 | 1e-39 | 148 | 32 | 53 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0050810; P:regulation of steroid biosynthetic process; IDA:RGD. | 86 | A3PXS9 | 283 | Y1918_MYCSJ Uncharacterized oxidoreductase Mj... | 303 | 1e-39 | 147 | 36 | 50 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 87 | P28475 | 310 | S6PD_MALDO NADP-dependent D-sorbitol-6-phosph... | 301 | 6e-39 | 145 | 32 | 53 | | | | | | | | | | | GO:0047641; F:aldose-6-phosphate reductase (NADPH) activity; IEA:EC. | | | | | | | | | | | 88 | Q8K023 | 323 | AKC1H_MOUSE Aldo-keto reductase family 1 memb... | 300 | 6e-39 | 145 | 33 | 53 | | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0007567; P:parturition; IMP:MGI.::GO:0006709; P:progesterone catabolic process; IDA:MGI. | 89 | A1T726 | 279 | Y2161_MYCVP Uncharacterized oxidoreductase Mv... | 302 | 1e-38 | 144 | 36 | 51 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 90 | A4TE41 | 279 | Y4205_MYCGI Uncharacterized oxidoreductase Mf... | 308 | 2e-38 | 144 | 35 | 50 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 91 | A1UEC6 | 276 | Y1985_MYCSK Uncharacterized oxidoreductase Mk... | 275 | 2e-38 | 143 | 36 | 52 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |