rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P45377 | 316 | ALD2_MOUSE Aldose reductase-related protein 2... | 324 | 2e-47 | 168 | 35 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 32 | O80944 | 311 | AKRC8_ARATH Aldo-keto reductase family 4 memb... | 281 | 3e-47 | 167 | 37 | 55 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:UniProtKB.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB. | 33 | Q9JII6 | 325 | AK1A1_MOUSE Alcohol dehydrogenase [NADP(+)] O... | 308 | 5e-47 | 167 | 35 | 56 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI.::GO:0047939; F:L-glucuronate reductase activity; IDA:MGI. | | | | | | | | | | GO:0046185; P:aldehyde catabolic process; IDA:MGI.::GO:0042840; P:D-glucuronate catabolic process; IDA:MGI.::GO:0019853; P:L-ascorbic acid biosynthetic process; IDA:MGI. | 34 | P52898 | 323 | DDBX_BOVIN Dihydrodiol dehydrogenase 3 OS=Bos... | 296 | 5e-47 | 167 | 37 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 35 | P80508 | 323 | PE2R_RABIT Prostaglandin-E(2) 9-reductase OS=... | 333 | 5e-47 | 167 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 36 | Q6W8P9 | 323 | AK1CO_HORSE Aldo-keto reductase family 1 memb... | 322 | 1e-46 | 166 | 35 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 37 | A0QV10 | 275 | Y2408_MYCS2 Uncharacterized oxidoreductase MS... | 276 | 2e-46 | 165 | 37 | 55 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | P05980 | 323 | PGFS1_BOVIN Prostaglandin F synthase 1 OS=Bos... | 323 | 5e-46 | 165 | 34 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 39 | P52897 | 323 | PGFS2_BOVIN Prostaglandin F synthase 2 OS=Bos... | 296 | 5e-46 | 165 | 36 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 40 | Q4R802 | 320 | AKCL2_MACFA 1,5-anhydro-D-fructose reductase ... | 284 | 6e-46 | 164 | 36 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 41 | P22045 | 284 | P100_LEIMA Probable reductase OS=Leishmania m... | 277 | 9e-46 | 163 | 36 | 55 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 42 | P17516 | 323 | AK1C4_HUMAN Aldo-keto reductase family 1 memb... | 333 | 1e-45 | 164 | 34 | 54 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:ProtInc.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0015125; F:bile acid transmembrane transporter activity; TAS:ProtInc.::GO:0047743; F:chlordecone reductase activity; IEA:EC.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; TAS:ProtInc.::GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB. | 43 | Q91WR5 | 323 | AK1CL_MOUSE Aldo-keto reductase family 1 memb... | 285 | 1e-45 | 164 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033764; F:steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IDA:MGI. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 44 | P51635 | 325 | AK1A1_RAT Alcohol dehydrogenase [NADP(+)] OS=... | 308 | 2e-45 | 163 | 35 | 56 | | | | | | | | | | | | | | | | | | | | | | 45 | Q6AYQ2 | 318 | AK1CL_RAT Aldo-keto reductase family 1 member... | 298 | 4e-45 | 162 | 37 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 46 | Q95JH5 | 323 | AK1C4_MACFA Aldo-keto reductase family 1 memb... | 333 | 5e-45 | 162 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC. | | | | | | | | | | | 47 | Q04828 | 323 | AK1C1_HUMAN Aldo-keto reductase family 1 memb... | 314 | 7e-45 | 162 | 36 | 55 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IDA:UniProtKB.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0015721; P:bile acid and bile salt transport; TAS:UniProtKB.::GO:0008206; P:bile acid metabolic process; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0042632; P:cholesterol homeostasis; TAS:UniProtKB.::GO:0030299; P:intestinal cholesterol absorption; TAS:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0046683; P:response to organophosphorus; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; NAS:UniProtKB. | 48 | P52895 | 323 | AK1C2_HUMAN Aldo-keto reductase family 1 memb... | 314 | 7e-45 | 162 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0034694; P:response to prostaglandin stimulus; IDA:UniProtKB. | 49 | Q5U1Y4 | 301 | AKCL2_RAT 1,5-anhydro-D-fructose reductase OS... | 288 | 8e-45 | 161 | 38 | 59 | | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 50 | Q95JH4 | 323 | AK1C4_MACFU Aldo-keto reductase family 1 memb... | 333 | 1e-44 | 161 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC. | | | | | | | | | | | 51 | Q8ZI40 | 277 | DKGA_YERPE 2,5-diketo-D-gluconic acid reducta... | 289 | 2e-44 | 159 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC. | | | | | | | | | | GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW. | 52 | Q1XAA8 | 322 | AK1CN_HORSE Aldo-keto reductase family 1 memb... | 321 | 2e-44 | 160 | 35 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 53 | Q9M338 | 315 | AKRCB_ARATH Aldo-keto reductase family 4 memb... | 283 | 2e-44 | 160 | 38 | 55 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR. | 54 | Q9DCT1 | 301 | AKCL2_MOUSE 1,5-anhydro-D-fructose reductase ... | 287 | 2e-44 | 160 | 37 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 55 | O08782 | 316 | ALD2_CRIGR Aldose reductase-related protein 2... | 322 | 3e-44 | 160 | 34 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 56 | Q3ZCJ2 | 325 | AK1A1_BOVIN Alcohol dehydrogenase [NADP(+)] O... | 310 | 3e-44 | 160 | 35 | 55 | | | | | | | | | | | | | | | | | | | | | | 57 | P23457 | 322 | DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase... | 309 | 4e-44 | 159 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC. | | | | | | | | | | GO:0021766; P:hippocampus development; IEP:RGD.::GO:0008202; P:steroid metabolic process; TAS:RGD. | 58 | Q46857 | 275 | DKGA_ECOLI 2,5-diketo-D-gluconic acid reducta... | 287 | 8e-44 | 157 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050580; F:2,5-didehydrogluconate reductase activity; IDA:EcoCyc. | | | | | | | | | | GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0009438; P:methylglyoxal metabolic process; EXP:EcoCyc. | 59 | Q95JH6 | 323 | AK1C1_MACFU Aldo-keto reductase family 1 memb... | 302 | 1e-43 | 158 | 36 | 57 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 60 | Q8XBT6 | 275 | DKGA_ECO57 2,5-diketo-D-gluconic acid reducta... | 287 | 1e-43 | 157 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC. | | | | | | | | | | GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW. | 61 | Q5REQ0 | 323 | AK1C1_PONAB Aldo-keto reductase family 1 memb... | 303 | 2e-43 | 158 | 36 | 55 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. |