Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR136W
Length:
2368
Number of sequences:
5887
Description:
YBR136W MEC1 SGDID:S000000340, Chr II from 505668-512774, Genome Release 64-1-1, Verified ORF, "Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for cell cycle arrest and transcriptional responses prompted by damaged or unreplicated DNA; monitors and participates in meiotic recombination"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P42338    1070   PK3CB_HUMAN Phosphatidylinositol 4,5-bisphosp...1160.03     43.5     29     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:ProtInc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.
GO:0000187; P:activation of MAPK activity; TAS:ProtInc.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0070527; P:platelet aggregation; TAS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; TAS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
122P42356    2044   PI4KA_HUMAN Phosphatidylinositol 4-kinase alp...670.065     42.4     33     58GO:0005798; C:Golgi-associated vesicle; TAS:ProtInc.
GO:0004430; F:1-phosphatidylinositol 4-kinase activity; TAS:ProtInc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:ProtInc.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0007268; P:synaptic transmission; TAS:ProtInc.
123Q0WPX9    1116   P4KB2_ARATH Phosphatidylinositol 4-kinase 2 O...840.072     42.4     31     54GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.
GO:0004430; F:1-phosphatidylinositol 4-kinase activity; ISS:UniProtKB.::GO:0005488; F:binding; IEA:InterPro.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro.
GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0009860; P:pollen tube growth; IGI:TAIR.::GO:0048768; P:root hair cell tip growth; IGI:TAIR.
124Q9FMJ0    1121   P4KB1_ARATH Phosphatidylinositol 4-kinase bet...710.075     42     32     55GO:0030659; C:cytoplasmic vesicle membrane; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0035619; C:root hair tip; IDA:TAIR.
GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IDA:UniProtKB.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro.::GO:0043424; F:protein histidine kinase binding; IPI:UniProtKB.::GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0009860; P:pollen tube growth; IGI:TAIR.::GO:0048768; P:root hair cell tip growth; IGI:TAIR.
125O00329    1044   PK3CD_HUMAN Phosphatidylinositol 4,5-bisphosp...1760.087     42     23     40GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.
GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0035754; P:B cell chemotaxis; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0001816; P:cytokine production; TAS:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0002551; P:mast cell chemotaxis; TAS:UniProtKB.::GO:0043303; P:mast cell degranulation; TAS:UniProtKB.::GO:0060374; P:mast cell differentiation; TAS:UniProtKB.::GO:0035747; P:natural killer cell chemotaxis; TAS:UniProtKB.::GO:0001779; P:natural killer cell differentiation; TAS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.::GO:0072672; P:neutrophil extravasation; TAS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0006468; P:protein phosphorylation; NAS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; TAS:UniProtKB.::GO:0010818; P:T cell chemotaxis; TAS:UniProtKB.::GO:0030217; P:T cell differentiation; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:UniProtKB.
126P38811    3744   TRA1_YEAST Transcription-associated protein 1...1610.11     42     29     43GO:0070209; C:ASTRA complex; IDA:SGD.::GO:0035267; C:NuA4 histone acetyltransferase complex; IPI:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006281; P:DNA repair; IDA:SGD.::GO:0016573; P:histone acetylation; IDA:GOC.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
127P54674    1857   PI3K2_DICDI Phosphatidylinositol 3-kinase 2 O...2940.11     41.6     21     40GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0031252; C:cell leading edge; TAS:dictyBase.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006928; P:cellular component movement; IGI:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IGI:dictyBase.::GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:dictyBase.::GO:0050919; P:negative chemotaxis; IGI:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0045761; P:regulation of adenylate cyclase activity; IMP:dictyBase.::GO:0022604; P:regulation of cell morphogenesis; IGI:dictyBase.::GO:0051591; P:response to cAMP; IGI:dictyBase.
128O02811    2043   PI4KA_BOVIN Phosphatidylinositol 4-kinase alp...670.12     41.6     33     58
GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro.
GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
129Q6DF78    782   PDXD1_XENLA Pyridoxal-dependent decarboxylase...1660.13     41.2     24     41
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
130A4QPH2    592   PI4P2_HUMAN Putative phosphatidylinositol 4-k...1330.6     38.9     22     40
GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
131B0C8Q6    93   ACYP_ACAM1 Acylphosphatase OS=Acaryochloris m...730.84     35.8     29     51
GO:0003998; F:acylphosphatase activity; IEA:EC.
132A2BP40    450   GLMM_PROMS Phosphoglucosamine mutase OS=Proch...1525     35.8     28     50
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008966; F:phosphoglucosamine mutase activity; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
133Q5FKW5    879   SYV_LACAC Valine--tRNA ligase OS=Lactobacillu...1196     35.8     24     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004832; F:valine-tRNA ligase activity; IEA:EC.
GO:0006438; P:valyl-tRNA aminoacylation; IEA:InterPro.
records
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