Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR125C
Length:
393
Number of sequences:
5887
Description:
YBR125C PTC4 SGDID:S000000329, Chr II from 488380-487199, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic type 2C protein phosphatase (PP2C); identified as a high-copy number suppressor of cnb1 mpk1 synthetic lethality; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38089    393   PP2C4_YEAST Protein phosphatase 2C homolog 4 ...3930     820     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0006470; P:protein dephosphorylation; IDA:SGD.
2Q09172    370   PP2C2_SCHPO Protein phosphatase 2C homolog 2 ...3936e-50     177     32     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:PomBase.
GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:PomBase.::GO:0006470; P:protein dephosphorylation; IDA:PomBase.
3Q09173    414   PP2C3_SCHPO Protein phosphatase 2C homolog 3 ...3942e-46     169     34     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:PomBase.
GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:PomBase.::GO:0006470; P:protein dephosphorylation; IDA:PomBase.
4P34221    468   PP2C3_YEAST Protein phosphatase 2C homolog 3 ...3893e-45     167     30     47GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IGI:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:SGD.
5P39966    464   PP2C2_YEAST Protein phosphatase 2C homolog 2 ...3913e-43     161     29     47GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0000077; P:DNA damage checkpoint; IGI:SGD.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:SGD.
6O81716    355   P2C21_ARATH Probable protein phosphatase 2C 2...3828e-40     150     31     46GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IDA:TAIR.
7Q653S3    362   P2C70_ORYSJ Probable protein phosphatase 2C 7...3823e-39     149     32     45GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
8Q9SZ53    357   P2C60_ARATH Probable protein phosphatase 2C 6...3775e-39     148     32     45GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
9Q6ETK3    362   P2C11_ORYSJ Probable protein phosphatase 2C 1...3824e-37     143     31     46GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
10Q67UP9    368   P2C58_ORYSJ Probable protein phosphatase 2C 5...3964e-37     143     30     46GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
11P49596    356   PP2C2_CAEEL Probable protein phosphatase 2C T...3701e-34     136     31     44GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
12A0CUB5    295   PP2C5_PARTE Probable protein phosphatase 2C 5...3762e-34     134     31     45GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
13Q7K4Q5    662   Y0417_DROME Probable protein phosphatase CG10...1020.001     45.1     35     50GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; NAS:FlyBase.
GO:0006470; P:protein dephosphorylation; NAS:FlyBase.
14A0DSB3    295   PP2C6_PARTE Probable protein phosphatase 2C 6...3682e-33     131     31     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
15Q61074    542   PPM1G_MOUSE Protein phosphatase 1G OS=Mus mus...1010.23     37.4     32     47GO:0005634; C:nucleus; IDA:MGI.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0007050; P:cell cycle arrest; IDA:MGI.::GO:0006470; P:protein dephosphorylation; IDA:MGI.
16O15355    546   PPM1G_HUMAN Protein phosphatase 1G OS=Homo sa...1010.18     37.7     32     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.
17Q4R4V2    547   PPM1G_MACFA Protein phosphatase 1G OS=Macaca ...1010.13     38.1     32     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
18P79126    543   PPM1G_BOVIN Protein phosphatase 1G OS=Bos tau...980.22     37.4     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
19P35814    382   PPM1A_RABIT Protein phosphatase 1A OS=Oryctol...3756e-29     119     29     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase.
20P20650    382   PPM1A_RAT Protein phosphatase 1A OS=Rattus no...3757e-29     119     29     44GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.
21O62829    382   PPM1A_BOVIN Protein phosphatase 1A OS=Bos tau...3759e-29     119     29     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase.
22P49443    382   PPM1A_MOUSE Protein phosphatase 1A OS=Mus mus...3751e-28     119     29     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.
GO:0006470; P:protein dephosphorylation; IDA:MGI.
23P36993    390   PPM1B_MOUSE Protein phosphatase 1B OS=Mus mus...3771e-28     119     29     45GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
24P35813    382   PPM1A_HUMAN Protein phosphatase 1A OS=Homo sa...3752e-28     118     29     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0033192; F:calmodulin-dependent protein phosphatase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0010991; P:negative regulation of SMAD protein complex assembly; IDA:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IDA:BHF-UCL.
25P49444    300   PP2C1_PARTE Protein phosphatase 2C 1 OS=Param...3782e-28     117     30     44GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
26A0BQL0    300   PP2C3_PARTE Probable protein phosphatase 2C 3...3784e-28     116     30     44GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
27O62830    484   PPM1B_BOVIN Protein phosphatase 1B OS=Bos tau...3776e-28     117     28     44GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
28P49595    491   PP2C1_CAEEL Probable protein phosphatase 2C F...950.0006     45.4     37     47GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
29A0BLX0    300   PP2C2_PARTE Probable protein phosphatase 2C 2...3782e-27     114     30     44GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
30O75688    479   PPM1B_HUMAN Protein phosphatase 1B OS=Homo sa...3772e-27     116     28     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.
31A0DTY1    301   PP2C4_PARTE Probable protein phosphatase 2C 4...3793e-27     113     29     45GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
records
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