Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR125C
Length:
393
Number of sequences:
5887
Description:
YBR125C PTC4 SGDID:S000000329, Chr II from 488380-487199, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic type 2C protein phosphatase (PP2C); identified as a high-copy number suppressor of cnb1 mpk1 synthetic lethality; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q9FKX4    385   P2C79_ARATH Probable protein phosphatase 2C 7...3020.000005     51.6     21     41GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
182O14189    444   PP2C5_SCHPO Protein phosphatase 2C homolog C1...1600.000006     51.6     28     44GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.]
183Q6K6N7    518   P2C14_ORYSJ Probable protein phosphatase 2C 1...2170.000008     51.6     26     41
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
184Q01631    2300   CYAA_NEUCR Adenylate cyclase OS=1257 / FGSC 9...1490.000008     52     30     43
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
185Q96MI6    270   PPM1M_HUMAN Protein phosphatase 1M OS=Homo sa...2360.000008     50.4     26     39GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008420; F:CTD phosphatase activity; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB.
GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
186Q7XVF9    520   P2C39_ORYSJ Probable protein phosphatase 2C 3...2540.00001     51.2     23     43
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
187P46014    581   P2C70_ARATH Protein phosphatase 2C 70 OS=Arab...1800.00001     50.8     26     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:TAIR.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0009934; P:regulation of meristem structural organization; IMP:TAIR.::GO:0007165; P:signal transduction; IDA:TAIR.
188A3AZ89    593   P2C46_ORYSJ Putative protein phosphatase 2C 4...2300.00002     50.4     22     41
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
189Q8H063    392   P2C29_ORYSJ Probable protein phosphatase 2C 2...2770.00002     50.1     22     40GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
190Q9LZ86    674   P2C66_ARATH Probable protein phosphatase 2C 6...2970.00002     50.1     22     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
191Q9SD12    379   P2C46_ARATH Probable protein phosphatase 2C 4...2100.00004     48.9     22     44GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
192Q9SUF4    212   P2C53_ARATH Putative protein phosphatase 2C 5...1960.00006     47.4     23     43
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
193O15297    605   PPM1D_HUMAN Protein phosphatase 1D OS=Homo sa...2750.00007     48.5     24     39GO:0005634; C:nucleus; TAS:ProtInc.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0009314; P:response to radiation; TAS:ProtInc.
194A3CCP9    499   P2C76_ORYSJ Putative protein phosphatase 2C 7...4190.0001     47.8     22     36
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
195Q9SL76    1094   P2C19_ARATH Protein phosphatase 2C and cyclic...1880.0001     47.8     23     43GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.
196Q9QZ67    598   PPM1D_MOUSE Protein phosphatase 1D OS=Mus mus...3280.0001     47.8     23     41GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:MGI.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0009617; P:response to bacterium; IMP:MGI.
197Q9M9C6    436   P2C15_ARATH Probable protein phosphatase 2C 1...2630.0002     46.6     25     39
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
198Q93YS2    528   P2C51_ARATH Probable protein phosphatase 2C 5...2670.0003     46.2     23     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
199Q8RWN7    856   P2C32_ARATH Protein phosphatase 2C 32 OS=Arab...1660.0004     46.2     25     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IDA:TAIR.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
GO:0010074; P:maintenance of meristem identity; IGI:TAIR.::GO:0009934; P:regulation of meristem structural organization; IGI:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IGI:TAIR.
200Q7XJ53    348   P2C35_ARATH Probable protein phosphatase 2C 3...1840.0004     45.4     24     43GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
201Q67J17    422   P2C69_ORYSJ Probable protein phosphatase 2C 6...2110.0006     45.4     26     41
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
202P49606    2493   CYAA_USTMA Adenylate cyclase OS=Ustilago mayd...810.0006     45.8     33     56
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
203P23466    1839   CYAA_LACKL Adenylate cyclase OS=Lachancea klu...1380.0006     45.8     27     43
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
204Q54WS9    1006   Y9461_DICDI Probable protein phosphatase DDB_...2930.0008     45.4     24     40
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
205Q8CF89    502   TAB1_MOUSE TGF-beta-activated kinase 1 and MA...1850.001     44.7     24     44
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0019209; F:kinase activator activity; IMP:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000185; P:activation of MAPKKK activity; IMP:MGI.::GO:0003007; P:heart morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:MGI.
206P08678    2026   CYAA_YEAST Adenylate cyclase OS=Saccharomyces...1440.001     45.1     26     43GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0004016; F:adenylate cyclase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
207Q9ZV25    654   P2C23_ARATH Probable protein phosphatase 2C 2...2280.001     44.7     22     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0048366; P:leaf development; IMP:TAIR.
208Q9M1V8    423   P2C50_ARATH Putative protein phosphatase 2C 5...3860.002     43.5     21     34
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
209Q6ZGY0    596   P2C26_ORYSJ Probable protein phosphatase 2C 2...2350.002     43.9     23     43
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
210Q01513    2145   CYAA_PODAS Adenylate cyclase OS=Podospora ans...850.002     43.9     36     52
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
211Q15750    504   TAB1_HUMAN TGF-beta-activated kinase 1 and MA...1850.003     43.1     24     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0000185; P:activation of MAPKKK activity; TAS:ProtInc.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
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