Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR115C
Length:
1392
Number of sequences:
5887
Description:
YBR115C LYS2 SGDID:S000000319, Chr II from 473926-469748, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P07702    1392   LYS2_YEAST L-aminoadipate-semialdehyde dehydr...13920     2880     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004043; F:L-aminoadipate-semialdehyde dehydrogenase activity; IDA:SGD.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0019878; P:lysine biosynthetic process via aminoadipic acid; IDA:SGD.
2Q6FMI5    1374   LYS2_CANGA L-aminoadipate-semialdehyde dehydr...13860     2067     71     83
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004043; F:L-aminoadipate-semialdehyde dehydrogenase activity; IEA:EC.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
3Q12572    1391   LYS2_CANAX L-aminoadipate-semialdehyde dehydr...13970     1522     56     71
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004043; F:L-aminoadipate-semialdehyde dehydrogenase activity; IEA:EC.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
4Q75BB3    1385   LYS2_ASHGO L-aminoadipate-semialdehyde dehydr...13880     1493     55     71
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004043; F:L-aminoadipate-semialdehyde dehydrogenase activity; IEA:EC.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
5P40976    1419   LYS2_SCHPO L-aminoadipate-semialdehyde dehydr...14280     1358     50     66GO:0005829; C:cytosol; IDA:PomBase.
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000062; F:fatty-acyl-CoA binding; IDA:PomBase.::GO:0004043; F:L-aminoadipate-semialdehyde dehydrogenase activity; IDA:PomBase.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0009085; P:lysine biosynthetic process; IDA:PomBase.
6O74298    1409   LYS2_PENCH L-aminoadipate-semialdehyde dehydr...14200     1337     50     66
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004043; F:L-aminoadipate-semialdehyde dehydrogenase activity; IEA:EC.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
7Q70LM4    5085   LGRD_BREPA Linear gramicidin synthase subunit...6808e-60     231     26     44
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0004043; F:L-aminoadipate-semialdehyde dehydrogenase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
8O30409    6486   TYCC_BREPA Tyrocidine synthase 3 OS=Brevibaci...8974e-66     252     26     43
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
9O68006    5255   BACA_BACLI Bacitracin synthase 1 OS=Bacillus ...6833e-45     184     25     43
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0008881; F:glutamate racemase activity; IEA:EC.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
10P0C064    4450   GRSB_BREBE Gramicidin S synthase 2 OS=Breviba...8872e-60     233     24     42
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
11P0C063    4451   GRSB_ANEMI Gramicidin S synthase 2 OS=Aneurin...9031e-60     234     24     42
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
12P45745    2378   DHBF_BACSU Dimodular nonribosomal peptide syn...9801e-71     269     26     42
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
GO:0009058; P:biosynthetic process; IEA:InterPro.
13O30408    3587   TYCB_BREPA Tyrocidine synthase 2 OS=Brevibaci...7442e-65     249     26     45
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0047462; F:phenylalanine racemase (ATP-hydrolyzing) activity; IEA:EC.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
14Q70LM5    7756   LGRC_BREPA Linear gramicidin synthase subunit...8667e-59     228     25     41
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
15O68008    6359   BACC_BACLI Bacitracin synthase 3 OS=Bacillus ...9691e-55     218     25     42
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0047689; F:aspartate racemase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0047462; F:phenylalanine racemase (ATP-hydrolyzing) activity; IEA:EC.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
16P94459    3603   PPSD_BACSU Plipastatin synthase subunit D OS=...8311e-49     198     24     43
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
17O31782    5488   PKSN_BACSU Polyketide synthase PksN OS=Bacill...700.23     40     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
GO:0009058; P:biosynthetic process; IEA:InterPro.
18P27206    3587   SRFAA_BACSU Surfactin synthase subunit 1 OS=B...9812e-59     230     24     42
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
19Q04747    3583   SRFAB_BACSU Surfactin synthase subunit 2 OS=B...9249e-55     215     24     41
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
20Q9R9I9    2609   MYCC_BACIU Mycosubtilin synthase subunit C OS...7803e-55     216     24     42
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
21Q70LM6    5162   LGRB_BREPA Linear gramicidin synthase subunit...9615e-54     213     24     41
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
22Q9R9J0    5369   MYCB_BACIU Mycosubtilin synthase subunit B OS...2350.18     40     23     38
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
23P39846    2560   PPSB_BACSU Plipastatin synthase subunit B OS=...9686e-64     244     24     43
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
24O31827    1279   PPSE_BACSU Plipastatin synthase subunit E OS=...7642e-63     241     26     44
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
25O68007    2607   BACB_BACLI Bacitracin synthase 2 OS=Bacillus ...9752e-58     226     23     42
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0050157; F:ornithine racemase activity; IEA:EC.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
26P39847    2555   PPSC_BACSU Plipastatin synthase subunit C OS=...8023e-57     223     24     42
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
27Q08787    1275   SRFAC_BACSU Surfactin synthase subunit 3 OS=B...7693e-59     228     24     43
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
28P09095    1088   TYCA_BREPA Tyrocidine synthase 1 OS=Brevibaci...7016e-59     226     26     44
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0047462; F:phenylalanine racemase (ATP-hydrolyzing) activity; IEA:EC.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
29P40806    5043   PKSJ_BACSU Polyketide synthase PksJ OS=Bacill...5490.0000000007     68.2     22     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
30P39845    2561   PPSA_BACSU Plipastatin synthase subunit A OS=...9773e-57     223     24     42
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
31Q70LM7    2273   LGRA_BREPA Linear gramicidin synthase subunit...8113e-52     206     25     43
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
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