Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR097W
Length:
1454
Number of sequences:
5887
Description:
YBR097W VPS15 SGDID:S000000301, Chr II from 436951-441315, Genome Release 64-1-1, Verified ORF, "Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421Q03145    977   EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus m...1760.0002     49.3     25     45GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048320; P:axial mesoderm formation; IMP:MGI.::GO:0046849; P:bone remodeling; IMP:UniProtKB.::GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0070309; P:lens fiber cell morphogenesis; IDA:UniProtKB.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0021915; P:neural tube development; IMP:MGI.::GO:0030182; P:neuron differentiation; IDA:MGI.::GO:0060035; P:notochord cell development; IMP:MGI.::GO:0014028; P:notochord formation; IMP:MGI.::GO:0001649; P:osteoblast differentiation; IMP:UniProtKB.::GO:0030316; P:osteoclast differentiation; IDA:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045765; P:regulation of angiogenesis; IDA:UniProtKB.::GO:0043535; P:regulation of blood vessel endothelial cell migration; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0010591; P:regulation of lamellipodium assembly; ISS:UniProtKB.::GO:0070848; P:response to growth factor stimulus; ISS:UniProtKB.::GO:0001501; P:skeletal system development; IMP:MGI.::GO:0035121; P:tail morphogenesis; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI.
422Q38868    541   CDPK9_ARATH Calcium-dependent protein kinase ...2740.0003     49.3     23     43GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; TAS:TAIR.
423P97477    395   AURKA_MOUSE Aurora kinase A OS=Mus musculus (...1700.0003     48.9     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
424Q1DUU8    364   HOG1_COCIM Mitogen-activated protein kinase H...1430.0003     48.5     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
425Q9C562    479   CIPKA_ARATH CBL-interacting serine/threonine-...2140.0003     48.9     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
426Q2WGK3    356   HOG1_TRIHA Mitogen-activated protein kinase h...1430.0003     48.5     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
427Q6CCB0    405   SSN3_YARLI Serine/threonine-protein kinase SS...2610.0003     48.9     24     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
428Q4WHP3    815   STE20_ASPFU Serine/threonine-protein kinase s...1860.0003     49.3     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
429Q6P3W7    929   SCYL2_HUMAN SCY1-like protein 2 OS=Homo sapie...1870.0003     49.3     26     46GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0005102; F:receptor binding; IPI:BHF-UCL.
GO:0008333; P:endosome to lysosome transport; IDA:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:2000370; P:positive regulation of clathrin-mediated endocytosis; IDA:BHF-UCL.::GO:0002092; P:positive regulation of receptor internalization; IDA:BHF-UCL.::GO:2000286; P:receptor internalization involved in canonical Wnt receptor signaling pathway; IDA:BHF-UCL.
430Q11053    626   PKNH_MYCTU Probable serine/threonine-protein ...1760.0003     49.3     25     43GO:0005887; C:integral to plasma membrane; IDA:MTBBASE.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE.
GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0045926; P:negative regulation of growth; IMP:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0046890; P:regulation of lipid biosynthetic process; IMP:MTBBASE.::GO:0052572; P:response to host immune response; IEP:MTBBASE.::GO:0006950; P:response to stress; IEP:MTBBASE.
431Q9JKV2    629   ICK_MOUSE Serine/threonine-protein kinase ICK...2370.0003     49.3     24     41GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
432Q8R9T6    625   PKN1_THETN Probable serine/threonine-protein ...2350.0003     48.9     25     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
433Q9ESG9    490   PMYT1_MOUSE Membrane-associated tyrosine- and...2280.0003     48.9     25     39GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
434Q6C7U8    294   PHO85_YARLI Negative regulator of the PHO sys...1270.0003     48.1     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
435Q9LM33    589   MPK8_ARATH Mitogen-activated protein kinase 8...1430.0003     48.9     29     48GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IPI:TAIR.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0042542; P:response to hydrogen peroxide; IEP:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IEP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.
436Q0D4B2    525   CIPKL_ORYSJ CBL-interacting protein kinase 21...1560.0003     48.9     25     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
437Q9Y7T4    830   ATG1_SCHPO Serine/threonine-protein kinase at...2230.0003     49.3     26     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0032258; P:CVT pathway; NAS:PomBase.::GO:0016236; P:macroautophagy; IC:PomBase.::GO:0016239; P:positive regulation of macroautophagy; ISS:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
438P43250    576   GRK6_HUMAN G protein-coupled receptor kinase ...1710.0003     48.9     29     44GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
439P32562    705   CDC5_YEAST Cell cycle serine/threonine-protei...3120.0003     48.9     24     41GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000922; C:spindle pole; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:SGD.::GO:0090306; P:spindle assembly involved in meiosis; IMP:SGD.::GO:0070194; P:synaptonemal complex disassembly; IGI:SGD.
440Q6H7U5    493   CIPKQ_ORYSJ CBL-interacting protein kinase 26...2150.0003     48.9     22     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
441Q2PQN9    292   CDK5_GLOMM Cyclin-dependent kinase 5 homolog ...1280.0003     48.1     30     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
442P53668    647   LIMK1_MOUSE LIM domain kinase 1 OS=Mus muscul...2020.0003     48.9     23     47GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045773; P:positive regulation of axon extension; IGI:MGI.
443Q54CY9    313   MYLKD_DICDI Probable myosin light chain kinas...2190.0003     48.1     24     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
444Q9C9U4    576   MPK15_ARATH Mitogen-activated protein kinase ...1430.0003     48.9     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
445P52304    576   POLO_DROME Serine/threonine-protein kinase po...2170.0003     48.9     21     44GO:0005813; C:centrosome; IDA:FlyBase.::GO:0000940; C:condensed chromosome outer kinetochore; IDA:FlyBase.::GO:0005874; C:microtubule; IDA:FlyBase.::GO:0030496; C:midbody; IDA:FlyBase.::GO:0005635; C:nuclear envelope; IDA:FlyBase.::GO:0000922; C:spindle pole; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.
GO:0000910; P:cytokinesis; TAS:FlyBase.::GO:0007060; P:male meiosis chromosome segregation; TAS:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0007344; P:pronuclear fusion; IMP:FlyBase.::GO:0035046; P:pronuclear migration; IMP:FlyBase.::GO:0008104; P:protein localization; NAS:FlyBase.::GO:0035044; P:sperm aster formation; IMP:FlyBase.::GO:0007058; P:spindle assembly involved in female meiosis II; IMP:FlyBase.
446Q6C4M9    386   HOG1_YARLI Mitogen-activated protein kinase H...1430.0003     48.5     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
447Q5R4K3    802   KS6A5_PONAB Ribosomal protein S6 kinase alpha...1980.0004     48.5     23     44GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0043990; P:histone H2A-S1 phosphorylation; ISS:UniProtKB.::GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
448Q9NI63    533   PMYT1_DROME Membrane-associated tyrosine- and...2910.0004     48.5     24     41GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:UniProtKB.
GO:0007143; P:female meiosis; IMP:FlyBase.::GO:0048142; P:germarium-derived cystoblast division; IMP:FlyBase.::GO:0007140; P:male meiosis; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0045930; P:negative regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0048137; P:spermatocyte division; IMP:FlyBase.::GO:0007284; P:spermatogonial cell division; IMP:FlyBase.
449Q23915    1094   KINX_DICDI Probable serine/threonine-protein ...3200.0004     48.9     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
450Q0JI49    502   CIPKB_ORYSJ CBL-interacting protein kinase 11...2610.0004     48.5     21     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
451Q9HBY8    427   SGK2_HUMAN Serine/threonine-protein kinase Sg...1270.0004     48.5     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015459; F:potassium channel regulator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0017080; F:sodium channel regulator activity; NAS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032411; P:positive regulation of transporter activity; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006979; P:response to oxidative stress; TAS:ProtInc.
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