Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR097W
Length:
1454
Number of sequences:
5887
Description:
YBR097W VPS15 SGDID:S000000301, Chr II from 436951-441315, Genome Release 64-1-1, Verified ORF, "Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q09136    385   AAPK1_PIG 5'-AMP-activated protein kinase cat...2470.000002     55.1     25     45GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004679; F:AMP-activated protein kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
152P38615    370   RIM11_YEAST Serine/threonine-protein kinase R...1500.000002     55.1     29     49GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0030437; P:ascospore formation; IMP:SGD.::GO:0006508; P:proteolysis; IGI:SGD.::GO:0006950; P:response to stress; IGI:SGD.
153P14681    368   KSS1_YEAST Mitogen-activated protein kinase K...3170.000003     55.1     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.::GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:SGD.::GO:0008134; F:transcription factor binding; IPI:SGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.
154Q8GYQ5    372   MPK12_ARATH Mitogen-activated protein kinase ...2250.000003     55.1     24     44GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0009734; P:auxin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0080026; P:response to indolebutyric acid stimulus; IMP:TAIR.
155Q8T2I8    1167   SEPA_DICDI Serine/threonine-protein kinase se...2530.000003     55.8     27     40GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
156P27448    753   MARK3_HUMAN MAP/microtubule affinity-regulati...2480.000003     55.5     26     47GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
157Q7X996    443   CIPK2_ORYSJ CBL-interacting protein kinase 2 ...2170.000003     55.1     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
158Q5ZCI1    611   MPK10_ORYSJ Mitogen-activated protein kinase ...1470.000003     55.5     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
159Q13554    666   KCC2B_HUMAN Calcium/calmodulin-dependent prot...1920.000003     55.5     26     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:UniProtKB.::GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.::GO:0051823; P:regulation of synapse structural plasticity; TAS:UniProtKB.
160Q12222    375   YGK3_YEAST Glycogen synthase kinase-3 homolog...1210.000003     54.7     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IGI:SGD.
GO:0006508; P:proteolysis; IGI:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IGI:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
161Q5BAE1    426   SSN3_EMENI Serine/threonine-protein kinase ss...2470.000003     55.1     26     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
162Q13555    558   KCC2G_HUMAN Calcium/calmodulin-dependent prot...1920.000003     55.5     26     45GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030073; P:insulin secretion; NAS:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.::GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
163Q9HFF4    1023   PPK1_SCHPO Serine/threonine-protein kinase pp...2600.000003     55.5     23     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
164P22612    351   KAPCG_HUMAN cAMP-dependent protein kinase cat...2330.000003     54.7     25     44GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; TAS:ProtInc.
GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0008584; P:male gonad development; TAS:ProtInc.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome.
165Q8C1R0    372   TSSK5_MOUSE Testis-specific serine/threonine-...1750.000004     54.7     30     47
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
166Q923T9    529   KCC2G_MOUSE Calcium/calmodulin-dependent prot...1920.000004     55.1     26     45GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IMP:MGI.
167O74536    576   SNF1_SCHPO SNF1-like protein kinase ssp2 OS=S...2320.000004     55.1     27     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031593; F:polyubiquitin binding; TAS:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:2000766; P:negative regulation of cytoplasmic translation; ISS:PomBase.::GO:0046015; P:regulation of transcription by glucose; ISS:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
168P11730    527   KCC2G_RAT Calcium/calmodulin-dependent protei...1920.000004     55.1     26     45GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0006979; P:response to oxidative stress; IDA:RGD.
169Q6NSM8    1187   SIK3_DANRE Serine/threonine-protein kinase SI...2610.000004     55.5     26     47
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
170P22216    821   RAD53_YEAST Serine/threonine-protein kinase R...2180.000004     55.1     23     44GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:SGD.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0009202; P:deoxyribonucleoside triphosphate biosynthetic process; IMP:SGD.::GO:0006281; P:DNA repair; IMP:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD.
171Q9QYZ5    504   SMK3_MOUSE Sperm motility kinase 3 OS=Mus mus...1490.000004     54.7     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
172Q8IY84    436   NIM1_HUMAN Serine/threonine-protein kinase NI...2660.000005     54.3     25     45
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
173Q8IVW4    592   CDKL3_HUMAN Cyclin-dependent kinase-like 3 OS...2040.000005     54.7     30     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
174Q3MHJ9    542   KCC2B_BOVIN Calcium/calmodulin-dependent prot...1920.000006     54.7     26     44GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
175P05383    351   KAPCB_PIG cAMP-dependent protein kinase catal...2330.000006     53.9     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
176P50873    501   MRK1_YEAST Serine/threonine-protein kinase MR...2120.000006     54.3     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IGI:SGD.
GO:0042176; P:regulation of protein catabolic process; IGI:SGD.::GO:0006950; P:response to stress; IGI:SGD.
177A0AUV4    508   SMKY_MOUSE Sperm motility kinase Y OS=Mus mus...1830.000006     54.3     26     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
178Q9WVC6    431   SGK1_MOUSE Serine/threonine-protein kinase Sg...1790.000007     53.9     27     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IDA:MGI.
179P68182    351   KAPCB_RAT cAMP-dependent protein kinase catal...2330.000007     53.5     25     45GO:0005952; C:cAMP-dependent protein kinase complex; IDA:RGD.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; IC:RGD.
GO:0051447; P:negative regulation of meiotic cell cycle; IDA:RGD.
180P68181    351   KAPCB_MOUSE cAMP-dependent protein kinase cat...2330.000007     53.5     25     45GO:0005952; C:cAMP-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; TAS:UniProtKB.
181P68180    351   KAPCB_CRIGR cAMP-dependent protein kinase cat...2330.000007     53.5     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
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