UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR084W

Length:

975

Number of sequences:

5887

Description:

YBR084W MIS1 SGDID:S000000288, Chr II from 411054-413981, Genome Release 64-1-1, Verified ORF, "Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
301	Q74JC1	557	FTHS_LACJO Formate--tetrahydrofolate ligase O...	631	3e-120	385	38	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
302	Q043I0	559	FTHS_LACGA Formate--tetrahydrofolate ligase O...	633	1e-116	375	38	56
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
303	Q72GY9	543	FTHS_THET2 Formate--tetrahydrofolate ligase O...	616	2e-116	374	38	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
304	Q160C2	558	FTHS_ROSDO Formate--tetrahydrofolate ligase O...	148	5e-34	142	51	74
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
305	Q5FJY2	558	FTHS1_LACAC Formate--tetrahydrofolate ligase ...	634	5e-110	358	37	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
306	Q9HI67	536	FTHS_THEAC Formate--tetrahydrofolate ligase O...	620	2e-107	350	38	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
307	Q97CL3	536	FTHS_THEVO Formate--tetrahydrofolate ligase O...	620	2e-105	345	37	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
308	Q6KZM3	535	FTHS_PICTO Formate--tetrahydrofolate ligase O...	616	3e-105	344	36	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
309	Q5LNV0	558	FTHS_SILPO Formate--tetrahydrofolate ligase O...	148	2e-31	134	49	70
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
310	A9NE95	527	FTHS_ACHLI Formate--tetrahydrofolate ligase O...	612	1e-103	340	37	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
311	A0LE04	285	FOLD_MAGSM Bifunctional protein FolD OS=Magne...	287	9e-84	278	49	66
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
312	A5GAM5	280	FOLD_GEOUR Bifunctional protein FolD OS=Geoba...	287	1e-83	277	51	65
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
313	Q92BZ4	284	FOLD_LISIN Bifunctional protein FolD OS=Liste...	287	2e-83	276	47	69
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
314	Q5NP22	297	FOLD_ZYMMO Bifunctional protein FolD OS=Zymom...	289	6e-83	276	49	68
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
315	A7ZCH3	283	FOLD_CAMC1 Bifunctional protein FolD OS=Campy...	291	7e-83	275	48	69
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
316	Q39WH4	285	FOLD2_GEOMG Bifunctional protein FolD 2 OS=Ge...	286	2e-82	274	49	66
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
317	B3EJG9	298	FOLD_CHLPB Bifunctional protein FolD OS=Chlor...	290	2e-82	274	48	68
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
318	Q2RIB4	280	FOLD_MOOTA Bifunctional protein FolD OS=Moore...	287	4e-82	273	49	66
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
319	B9M769	280	FOLD_GEOSF Bifunctional protein FolD OS=Geoba...	287	2e-81	271	49	65
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
320	A7GXK2	288	FOLD_CAMC5 Bifunctional protein FolD OS=Campy...	287	4e-81	270	49	69
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
321	B3CLT4	295	FOLD_WOLPP Bifunctional protein FolD OS=Wolba...	287	4e-81	271	49	68
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
322	Q5GTK9	295	FOLD_WOLTR Bifunctional protein FolD OS=Wolba...	287	4e-81	270	49	67
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
323	Q2G338	297	FOLD_NOVAD Bifunctional protein FolD OS=Novos...	288	7e-81	270	49	66
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
324	A1VN60	281	FOLD_POLNA Bifunctional protein FolD OS=Polar...	287	8e-81	269	47	66
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
325	C1L2R6	284	FOLD_LISMC Bifunctional protein FolD OS=Liste...	289	2e-80	268	46	67
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
326	Q0KBW5	283	FOLD_CUPNH Bifunctional protein FolD OS=(Rals...	287	2e-80	268	48	64
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
327	B8DFW8	284	FOLD_LISMH Bifunctional protein FolD OS=Liste...	289	3e-80	268	46	67
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
328	Q2N7E3	298	FOLD_ERYLH Bifunctional protein FolD OS=Eryth...	288	4e-80	268	49	65
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
329	Q47IX6	284	FOLD_DECAR Bifunctional protein FolD OS=Dechl...	288	5e-80	267	49	65
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
330	Q73RS2	293	FOLD_TREDE Bifunctional protein FolD OS=Trepo...	289	5e-80	267	48	68
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
331	Q8Y7C5	284	FOLD_LISMO Bifunctional protein FolD OS=Liste...	287	7e-80	267	46	68
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.

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