Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR082C
Length:
148
Number of sequences:
5887
Description:
YBR082C UBC4 SGDID:S000000286, Chr II from 407027-406628,407169-407123, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-conjugating enzyme (E2), mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q06AA9    147   UB2D2_PIG Ubiquitin-conjugating enzyme E2 D2 ...1442e-85     253     80     90
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
32Q3ZCF7    147   UB2D3_BOVIN Ubiquitin-conjugating enzyme E2 D...1447e-85     252     80     90GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
33D3ZDK2    147   UB2D1_RAT Ubiquitin-conjugating enzyme E2 D1 ...1442e-84     251     80     90GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
34P61080    147   UB2D1_MOUSE Ubiquitin-conjugating enzyme E2 D...1442e-84     251     80     90GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
35P51668    147   UB2D1_HUMAN Ubiquitin-conjugating enzyme E2 D...1442e-84     251     80     90GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
36Q2TA10    147   UB2D1_BOVIN Ubiquitin-conjugating enzyme E2 D...1442e-84     251     80     90GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
37P70711    147   U2D2B_RAT Ubiquitin-conjugating enzyme E2 D2B...1442e-81     243     76     88
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
38Q6ZWY6    147   U2D2B_MOUSE Ubiquitin-conjugating enzyme E2 D...1442e-81     243     76     88
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
39Q9C9Y7    149   UBC12_ARATH Probable ubiquitin-conjugating en...1471e-75     229     70     89
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
40P52483    207   UB2E3_MOUSE Ubiquitin-conjugating enzyme E2 E...1475e-66     206     64     80GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
41Q969T4    207   UB2E3_HUMAN Ubiquitin-conjugating enzyme E2 E...1475e-66     206     64     80GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
42Q2T9X7    207   UB2E3_BOVIN Ubiquitin-conjugating enzyme E2 E...1475e-66     206     64     80GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
43P51965    193   UB2E1_HUMAN Ubiquitin-conjugating enzyme E2 E...1476e-66     205     64     80GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042296; F:ISG15 ligase activity; IDA:HGNC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
44Q96LR5    201   UB2E2_HUMAN Ubiquitin-conjugating enzyme E2 E...1477e-66     205     64     80GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042296; F:ISG15 ligase activity; IDA:HGNC.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
45P52482    193   UB2E1_MOUSE Ubiquitin-conjugating enzyme E2 E...1477e-66     205     64     80GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
46Q91W82    201   UB2E2_MOUSE Ubiquitin-conjugating enzyme E2 E...1478e-66     205     64     80
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
47P52485    232   UBCD2_DROME Ubiquitin-conjugating enzyme E2-2...1472e-64     202     64     78
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:FlyBase.
GO:0019915; P:lipid storage; IDA:FlyBase.
48Q9LJD7    182   COP10_ARATH Constitutive photomorphogenesis p...1463e-55     177     53     75GO:0005634; C:nucleus; IDA:TAIR.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.::GO:0010099; P:regulation of photomorphogenesis; IMP:TAIR.
49Q94490    148   UBCB_DICDI Ubiquitin conjugating enzyme E2 B ...1484e-49     160     52     70
GO:0004842; F:ubiquitin-protein ligase activity; ISS:dictyBase.
GO:0009653; P:anatomical structure morphogenesis; IMP:dictyBase.
50O13685    148   UBC13_SCHPO Ubiquitin-conjugating enzyme E2 1...1481e-46     154     50     64GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0071479; P:cellular response to ionizing radiation; IDA:PomBase.::GO:0006301; P:postreplication repair; IMP:PomBase.::GO:0070534; P:protein K63-linked ubiquitination; IDA:PomBase.
51Q86K32    154   UBE2N_DICDI Probable ubiquitin-conjugating en...1432e-45     151     52     66
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
52Q9UTN8    155   UBC14_SCHPO Ubiquitin-conjugating enzyme E2 1...1423e-45     151     49     65
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
53Q94A97    153   UBC35_ARATH Ubiquitin-conjugating enzyme E2 3...1433e-44     148     50     65GO:0031372; C:UBC13-MMS2 complex; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006301; P:postreplication repair; IGI:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0010039; P:response to iron ion; IMP:TAIR.::GO:0010053; P:root epidermal cell differentiation; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
54Q9C8X7    154   UBC31_ARATH Probable ubiquitin-conjugating en...1453e-44     148     52     70GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
55P35128    151   UBE2N_DROME Ubiquitin-conjugating enzyme E2 N...1473e-44     148     48     65
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0007412; P:axon target recognition; IMP:FlyBase.::GO:0007629; P:flight behavior; IMP:FlyBase.::GO:0007625; P:grooming behavior; IMP:FlyBase.::GO:0007630; P:jump response; IMP:FlyBase.::GO:0008594; P:photoreceptor cell morphogenesis; IMP:FlyBase.::GO:0072347; P:response to anesthetic; IMP:FlyBase.
56Q9FZ48    153   UBC36_ARATH Ubiquitin-conjugating enzyme E2 3...1433e-44     148     50     65GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0031372; C:UBC13-MMS2 complex; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0010039; P:response to iron ion; IMP:TAIR.::GO:0010053; P:root epidermal cell differentiation; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
57O74810    217   UBC1_SCHPO Ubiquitin-conjugating enzyme E2 1 ...1472e-43     148     46     64GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
58P52490    153   UBC13_YEAST Ubiquitin-conjugating enzyme E2 1...1461e-42     144     49     63GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0031371; C:ubiquitin conjugating enzyme complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0010994; P:free ubiquitin chain polymerization; IDA:SGD.::GO:0006301; P:postreplication repair; IMP:SGD.::GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; IDA:SGD.
59Q4R4I1    152   UBE2N_MACFA Ubiquitin-conjugating enzyme E2 N...1446e-42     142     47     63GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
60Q5R7J6    152   UBE2N_PONAB Ubiquitin-conjugating enzyme E2 N...1442e-41     141     47     63GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
61P61089    152   UBE2N_MOUSE Ubiquitin-conjugating enzyme E2 N...1442e-41     141     47     63GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0031372; C:UBC13-MMS2 complex; ISS:HGNC.::GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:HGNC.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0000729; P:DNA double-strand break processing; ISS:HGNC.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:HGNC.::GO:0016574; P:histone ubiquitination; ISS:HGNC.::GO:0045739; P:positive regulation of DNA repair; ISS:HGNC.::GO:0031058; P:positive regulation of histone modification; ISS:HGNC.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:HGNC.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:HGNC.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:HGNC.::GO:0006301; P:postreplication repair; ISS:HGNC.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0033182; P:regulation of histone ubiquitination; ISS:HGNC.::GO:0050852; P:T cell receptor signaling pathway; ISS:HGNC.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI.
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