Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR081C
Length:
1332
Number of sequences:
5887
Description:
YBR081C SPT7 SGDID:S000000285, Chr II from 405251-401253, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P35177    1332   SPT7_YEAST Transcriptional activator SPT7 OS=...13320     2719     100     100GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005198; F:structural molecule activity; IDA:SGD.
GO:0000747; P:conjugation with cellular fusion; IMP:SGD.::GO:0016573; P:histone acetylation; IDA:SGD.::GO:0006461; P:protein complex assembly; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2P87152    992   SPT7_SCHPO Transcriptional activator spt7 OS=...3155e-27     123     31     50GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0000124; C:SAGA complex; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0016573; P:histone acetylation; ISS:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; IC:PomBase.
3Q8UVR5    627   BAZ1A_XENLA Bromodomain adjacent to zinc fing...870.00000000003     71.6     38     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q6FTW5    546   GCN5_CANGA Histone acetyltransferase GCN5 OS=...1030.000000002     65.9     32     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q9Y7N0    578   BDF1_SCHPO SWR1 complex bromodomain subunit b...860.00000006     60.8     37     55GO:0000812; C:Swr1 complex; IDA:PomBase.
6O88379    1555   BAZ1A_MOUSE Bromodomain adjacent to zinc fing...1560.000000002     65.9     35     53GO:0000228; C:nuclear chromosome; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; TAS:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q9BXF3    1484   CECR2_HUMAN Cat eye syndrome critical region ...770.000000003     65.9     40     65
GO:0005515; F:protein binding; IPI:HGNC.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; NAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:HGNC.::GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
8Q9H0E9    1235   BRD8_HUMAN Bromodomain-containing protein 8 O...950.0000003     59.3     35     57GO:0005739; C:mitochondrion; IDA:HPA.::GO:0035267; C:NuA4 histone acetyltransferase complex; IDA:UniProtKB.
GO:0004887; F:thyroid hormone receptor activity; TAS:ProtInc.
GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
9Q9NRL2    1556   BAZ1A_HUMAN Bromodomain adjacent to zinc fing...870.000000006     64.7     41     62GO:0016590; C:ACF complex; TAS:BHF-UCL.::GO:0008623; C:chromatin accessibility complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; TAS:BHF-UCL.::GO:0006261; P:DNA-dependent DNA replication; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; NAS:BHF-UCL.
10Q6CXW4    516   GCN5_KLULA Histone acetyltransferase GCN5 OS=...1030.000000007     63.5     31     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q756G9    452   GCN5_ASHGO Histone acetyltransferase GCN5 OS=...1030.00000001     62.4     31     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12P35817    686   BDF1_YEAST Bromodomain-containing factor 1 OS...620.34     38.9     32     53GO:0000812; C:Swr1 complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0001047; F:core promoter binding; IDA:SGD.::GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.::GO:0001094; F:TFIID-class transcription factor binding; IDA:SGD.
GO:0006338; P:chromatin remodeling; IPI:SGD.::GO:0006281; P:DNA repair; IMP:SGD.::GO:0031452; P:negative regulation of heterochromatin assembly; IMP:SGD.::GO:1900051; P:positive regulation of histone exchange; IMP:SGD.::GO:0090054; P:regulation of chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0009301; P:snRNA transcription; IMP:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
13Q9UUK2    454   GCN5_SCHPO Histone acetyltransferase gcn5 OS=...770.00000003     61.6     36     65GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0000124; C:SAGA complex; IDA:PomBase.
GO:0010484; F:H3 histone acetyltransferase activity; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IGI:PomBase.::GO:0044154; P:histone H3-K14 acetylation; TAS:PomBase.::GO:0043971; P:histone H3-K18 acetylation; TAS:PomBase.::GO:0043972; P:histone H3-K23 acetylation; TAS:PomBase.::GO:0043970; P:histone H3-K9 acetylation; TAS:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q9UIF8    2168   BAZ2B_HUMAN Bromodomain adjacent to zinc fing...840.00000003     62.4     38     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; NAS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; NAS:BHF-UCL.
15Q03330    439   GCN5_YEAST Histone acetyltransferase GCN5 OS=...820.00000004     61.2     35     63GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:SGD.::GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0010484; F:H3 histone acetyltransferase activity; IDA:SGD.::GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.::GO:0003713; F:transcription coactivator activity; TAS:SGD.
GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q54DH8    2310   TAF1_DICDI Transcription initiation factor TF...1350.00000005     61.6     33     51GO:0005669; C:transcription factor TFIID complex; ISS:dictyBase.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004402; F:histone acetyltransferase activity; ISS:dictyBase.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:dictyBase.::GO:0006461; P:protein complex assembly; ISS:dictyBase.::GO:0006468; P:protein phosphorylation; ISS:dictyBase.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; ISS:dictyBase.
17Q9JHD1    813   KAT2B_MOUSE Histone acetyltransferase KAT2B O...910.00000005     61.2     31     63GO:0031672; C:A band; IDA:MGI.::GO:0042641; C:actomyosin; IDA:MGI.::GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.::GO:0031674; C:I band; IDA:MGI.::GO:0000776; C:kinetochore; IDA:MGI.
GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; IDA:MGI.::GO:0004468; F:lysine N-acetyltransferase activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:MGI.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q8WZM0    464   GCN5_YARLI Histone acetyltransferase GCN5 OS=...1020.00000007     60.5     31     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19B7ZS37    1698   BAZ2A_XENLA Bromodomain adjacent to zinc fing...750.00000007     61.2     40     60GO:0005677; C:chromatin silencing complex; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0033553; C:rDNA heterochromatin; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000183; P:chromatin silencing at rDNA; ISS:UniProtKB.::GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0016575; P:histone deacetylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20Q9DE13    2130   BAZ2B_CHICK Bromodomain adjacent to zinc fing...840.00000009     60.8     39     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21P13709    2038   FSH_DROME Homeotic protein female sterile OS=...990.0001     50.4     32     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:FlyBase.::GO:0007362; P:terminal region determination; IMP:FlyBase.
22P51123    2129   TAF1_DROME Transcription initiation factor TF...1250.000005     55.1     29     55GO:0005669; C:transcription factor TFIID complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035174; F:histone serine kinase activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0001129; F:TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly; IPI:FlyBase.::GO:0008134; F:transcription factor binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016573; P:histone acetylation; IDA:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0046425; P:regulation of JAK-STAT cascade; IMP:FlyBase.::GO:0000117; P:regulation of transcription involved in G2/M-phase of mitotic cell cycle; IMP:FlyBase.
23Q9UIF9    1905   BAZ2A_HUMAN Bromodomain adjacent to zinc fing...750.0000001     60.5     36     61GO:0005677; C:chromatin silencing complex; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0033553; C:rDNA heterochromatin; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; NAS:BHF-UCL.::GO:0003723; F:RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; NAS:UniProtKB.::GO:0000183; P:chromatin silencing at rDNA; ISS:UniProtKB.::GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0016575; P:histone deacetylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; NAS:UniProtKB.
24Q8R3B7    951   BRD8_MOUSE Bromodomain-containing protein 8 O...790.0000002     59.7     38     61GO:0035267; C:NuA4 histone acetyltransferase complex; ISS:UniProtKB.
GO:0043968; P:histone H2A acetylation; ISS:UniProtKB.::GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25Q91YE5    1889   BAZ2A_MOUSE Bromodomain adjacent to zinc fing...860.0000002     59.7     34     59GO:0005677; C:chromatin silencing complex; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0033553; C:rDNA heterochromatin; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0070577; F:histone acetyl-lysine binding; IDA:UniProtKB.::GO:0003723; F:RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000183; P:chromatin silencing at rDNA; IDA:UniProtKB.::GO:0006306; P:DNA methylation; IDA:UniProtKB.::GO:0016575; P:histone deacetylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26A2BIL7    1536   BAZ1B_DANRE Tyrosine-protein kinase BAZ1B OS=...800.0000004     58.5     38     58GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q67W65    1810   TAF1_ORYSJ Transcription initiation factor TF...830.0000005     58.2     39     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q9JHD2    830   KAT2A_MOUSE Histone acetyltransferase KAT2A O...950.0000006     57.8     31     62GO:0030914; C:STAGA complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0010484; F:H3 histone acetyltransferase activity; IDA:MGI.::GO:0043997; F:histone acetyltransferase activity (H4-K12 specific); IDA:MGI.
GO:0008283; P:cell proliferation; IMP:MGI.::GO:0044154; P:histone H3-K14 acetylation; IDA:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0022037; P:metencephalon development; IMP:MGI.::GO:0030901; P:midbrain development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0042981; P:regulation of apoptotic process; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001756; P:somitogenesis; IMP:MGI.::GO:0021537; P:telencephalon development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q6BGW1    455   GCN5_DEBHA Histone acetyltransferase GCN5 OS=...800.0000006     57.4     38     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q92830    837   KAT2A_HUMAN Histone acetyltransferase KAT2A O...950.0000006     57.8     31     62GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0030914; C:STAGA complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
GO:0010484; F:H3 histone acetyltransferase activity; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
GO:0006338; P:chromatin remodeling; TAS:ProtInc.::GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
31Q92831    832   KAT2B_HUMAN Histone acetyltransferase KAT2B O...870.0000007     57.4     30     63GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0016585; C:chromatin remodeling complex; IDA:UniProtKB.::GO:0000125; C:PCAF complex; NAS:UniProtKB.
GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; ISS:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0004468; F:lysine N-acetyltransferase activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0006338; P:chromatin remodeling; NAS:UniProtKB.::GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
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