Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR066C
Length:
220
Number of sequences:
5887
Description:
YBR066C NRG2 SGDID:S000000270, Chr II from 370699-370037, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38082    220   NRG2_YEAST Probable transcriptional regulator...2201e-163     458     100     100GO:0005634; C:nucleus; IDA:SGD.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042710; P:biofilm formation; IGI:SGD.::GO:0071475; P:cellular hyperosmotic salinity response; IGI:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IGI:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IGI:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q03125    231   NRG1_YEAST Transcriptional regulator NRG1 OS=...1921e-38     139     41     55GO:0005634; C:nucleus; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IMP:SGD.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042710; P:biofilm formation; IMP:SGD.::GO:0071475; P:cellular hyperosmotic salinity response; IMP:SGD.::GO:0071469; P:cellular response to alkalinity; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IGI:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0097201; P:negative regulation of transcription from RNA polymerase II promoter in response to stress; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IGI:SGD.
3P27705    504   MIG1_YEAST Regulatory protein MIG1 OS=Sacchar...650.00000000005     65.1     46     54GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005641; C:nuclear envelope lumen; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IDA:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
4Q9Z0Z7    446   KLF5_MOUSE Krueppel-like factor 5 OS=Mus musc...500.18     36.2     40     48GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IMP:MGI.::GO:0030033; P:microvillus assembly; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5P53035    382   MIG2_YEAST Regulatory protein MIG2 OS=Sacchar...610.000000001     60.8     46     54GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IDA:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
6P22227    288   ZFP42_MOUSE Zinc finger protein 42 OS=Mus mus...540.0002     45.1     39     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007286; P:spermatid development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q13351    362   KLF1_HUMAN Krueppel-like factor 1 OS=Homo sap...323.1     32.3     34     56GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8P30373    509   CKR1_CHICK Zinc finger protein CKR1 OS=Gallus...558.9     30.8     33     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
9P39943    394   MIG3_YEAST Transcription corepressor MIG3 OS=...570.000000002     59.7     49     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010768; P:negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; IMP:SGD.
10O35819    283   KLF6_RAT Krueppel-like factor 6 OS=Rattus nor...630.28     35.4     37     49GO:0005634; C:nucleus; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; IEP:RGD.
11P28698    734   MZF1_HUMAN Myeloid zinc finger 1 OS=Homo sapi...550.018     39.3     35     47GO:0005634; C:nucleus; IDA:HPA.
GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
12O14335    565   SCR1_SCHPO DNA-binding protein scr1 OS=Schizo...510.000000004     59.3     47     59GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13P52288    543   MIG1_KLUMA Regulatory protein MIG1 OS=Kluyver...530.000000004     59.3     47     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q8IWY8    852   ZSC29_HUMAN Zinc finger and SCAN domain-conta...550.023     39.3     36     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
15Q9EPW2    415   KLF15_MOUSE Krueppel-like factor 15 OS=Mus mu...480.008     40.4     40     60
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010001; P:glial cell differentiation; IDA:MGI.::GO:0015758; P:glucose transport; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q9Y7G2    574   MIG1_CANAX Regulatory protein MIG1 OS=Candida...620.000000005     58.9     44     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17Q13887    457   KLF5_HUMAN Krueppel-like factor 5 OS=Homo sap...500.28     35.4     40     48GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
18P50898    474   MIG1_KLULA Regulatory protein MIG1 OS=1267 / ...530.000000006     58.5     47     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q8BLM0    355   KLF8_MOUSE Krueppel-like factor 8 OS=Mus musc...480.087     37     44     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20Q96SZ4    725   ZSC10_HUMAN Zinc finger and SCAN domain-conta...550.52     35     31     45GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
21Q9UIH9    416   KLF15_HUMAN Krueppel-like factor 15 OS=Homo s...480.007     40.4     40     60GO:0005730; C:nucleolus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IC:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
22Q3TTC2    378   TYY2_MOUSE Transcription factor YY2 OS=Mus mu...520.0002     45.1     37     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23Q02446    784   SP4_HUMAN Transcription factor Sp4 OS=Homo sa...520.0000001     55.1     50     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q2FAY8    376   TYY2_RATRT Transcription factor YY2 OS=Rattus...520.0003     44.7     37     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25P0C6P6    376   TYY2_RAT Transcription factor YY2 OS=Rattus n...520.0003     44.7     37     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q01981    416   CREA_EMENI DNA-binding protein creA OS=194 / ...570.00000001     57.4     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q9HFS2    430   CREA_COCCA DNA-binding protein creA OS=Cochli...600.00000001     57.4     45     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q3URR7    782   ZSC10_MOUSE Zinc finger and SCAN domain-conta...697.6     31.2     30     36GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0048863; P:stem cell differentiation; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
29O95600    359   KLF8_HUMAN Krueppel-like factor 8 OS=Homo sap...480.076     37.4     44     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30O75840    302   KLF7_HUMAN Krueppel-like factor 7 OS=Homo sap...480.32     35     42     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31P08047    785   SP1_HUMAN Transcription factor Sp1 OS=Homo sa...520.00000007     55.5     50     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003690; F:double-stranded DNA binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
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