Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR066C
Length:
220
Number of sequences:
5887
Description:
YBR066C NRG2 SGDID:S000000270, Chr II from 370699-370037, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91O43829    449   ZF161_HUMAN Zinc finger protein 161 homolog O...572     33.1     28     47GO:0005634; C:nucleus; TAS:ProtInc.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
92Q60793    483   KLF4_MOUSE Krueppel-like factor 4 OS=Mus musc...480.97     33.9     38     50
GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009913; P:epidermal cell differentiation; IMP:MGI.::GO:0048730; P:epidermis morphogenesis; IMP:MGI.::GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0031077; P:post-embryonic camera-type eye development; IMP:MGI.::GO:0032526; P:response to retinoic acid; IDA:MGI.::GO:0019827; P:stem cell maintenance; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
93A1YEV9    473   ZSC21_GORGO Zinc finger and SCAN domain-conta...550.14     36.6     38     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
94Q8TAQ5    688   ZN420_HUMAN Zinc finger protein 420 OS=Homo s...551.1     33.9     36     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
95A2T7L7    473   ZSC21_PONPY Zinc finger and SCAN domain-conta...550.14     36.6     38     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
96O43474    513   KLF4_HUMAN Krueppel-like factor 4 OS=Homo sap...480.88     34.3     38     50GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:BHF-UCL.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0071363; P:cellular response to growth factor stimulus; IDA:BHF-UCL.::GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0007500; P:mesodermal cell fate determination; TAS:ProtInc.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0046985; P:positive regulation of hemoglobin biosynthetic process; IMP:BHF-UCL.::GO:0035166; P:post-embryonic hemopoiesis; IMP:BHF-UCL.::GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
97A1YG26    473   ZSC21_PANPA Zinc finger and SCAN domain-conta...550.14     36.6     38     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
98Q9Y5A6    473   ZSC21_HUMAN Zinc finger and SCAN domain-conta...550.14     36.6     38     53GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
99Q5EAC5    467   ZN410_BOVIN Zinc finger protein 410 OS=Bos ta...480.2     36.2     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
100A2T712    473   ZSC21_PANTR Zinc finger and SCAN domain-conta...550.16     36.6     38     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
101P36508    570   ZNF76_HUMAN Zinc finger protein 76 OS=Homo sa...520.001     43.1     40     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
102Q6ZN79    300   Z705A_HUMAN Zinc finger protein 705A OS=Homo ...1370.0000003     53.5     31     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
103A2VDQ7    687   ZN420_BOVIN Zinc finger protein 420 OS=Bos ta...551     33.9     36     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
104P10072    659   HKR1_HUMAN Krueppel-related zinc finger prote...530.093     37.4     38     49GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0007275; P:multicellular organismal development; NAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105Q66K89    784   E4F1_HUMAN Transcription factor E4F1 OS=Homo ...880.01     40.4     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0035497; F:cAMP response element binding; IDA:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0071850; P:mitotic cell cycle arrest; TAS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0010564; P:regulation of cell cycle process; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106Q9UEG4    869   ZN629_HUMAN Zinc finger protein 629 OS=Homo s...1040.034     38.5     27     46GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
107O08876    480   KLF10_RAT Krueppel-like factor 10 OS=Rattus n...980.23     35.8     24     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0042127; P:regulation of cell proliferation; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
108Q9Y5W3    355   KLF2_HUMAN Krueppel-like factor 2 OS=Homo sap...483.3     32.3     38     48GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
109Q642B9    556   ZNF18_RAT Zinc finger protein 18 OS=Rattus no...553.1     32.3     35     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
110Q499Z4    452   ZN672_HUMAN Zinc finger protein 672 OS=Homo s...555.7     31.6     35     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
111Q07231    555   ZSC21_MOUSE Zinc finger and SCAN domain-conta...550.12     36.6     38     53GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
112O89091    479   KLF10_MOUSE Krueppel-like factor 10 OS=Mus mu...380.64     34.7     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030282; P:bone mineralization; IMP:MGI.::GO:0045672; P:positive regulation of osteoclast differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:MGI.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
113P26632    511   EGR1_DANRE Early growth response protein 1 OS...610.0000005     52.8     39     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043010; P:camera-type eye development; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
114Q8TAF7    563   ZN461_HUMAN Zinc finger protein 461 OS=Homo s...558.3     31.2     35     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
115P39956    796   RPH1_YEAST DNA damage-responsive transcriptio...560.0000006     52.8     43     63GO:0005634; C:nucleus; IC:SGD.
GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:SGD.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
116Q9ET58    351   KLF2_RAT Krueppel-like factor 2 OS=Rattus nor...485.1     31.6     38     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0071347; P:cellular response to interleukin-1; IEP:RGD.::GO:0071356; P:cellular response to tumor necrosis factor; IEP:RGD.::GO:0032715; P:negative regulation of interleukin-6 production; IMP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117Q8K1S5    502   KLF11_MOUSE Krueppel-like factor 11 OS=Mus mu...580.000002     51.2     45     53GO:0005634; C:nucleus; IC:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
118Q60636    856   PRDM1_MOUSE PR domain zinc finger protein 1 O...290.28     35.8     48     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045165; P:cell fate commitment; IMP:MGI.::GO:0001892; P:embryonic placenta development; IMP:MGI.::GO:0007281; P:germ cell development; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001893; P:maternal placenta development; IMP:MGI.::GO:0030889; P:negative regulation of B cell proliferation; IDA:MGI.::GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045579; P:positive regulation of B cell differentiation; IDA:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119B4F7E9    568   ZNF76_RAT Zinc finger protein 76 OS=Rattus no...520.002     42.4     40     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
120P0C6Y7    796   PRDM9_RAT Histone-lysine N-methyltransferase ...520.004     41.6     40     58GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
121Q9BRH9    671   ZN251_HUMAN Zinc finger protein 251 OS=Homo s...552.2     32.7     36     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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