UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR066C

Length:

220

Number of sequences:

5887

Description:

YBR066C NRG2 SGDID:S000000270, Chr II from 370699-370037, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	O94131	420	CREA_GIBFU DNA-binding protein creA OS=monili...	87	0.00000006	55.5	32	52	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
62	O60304	480	ZN500_HUMAN Zinc finger protein 500 OS=Homo s...	59	0.00002	48.5	42	56	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
63	Q62445	782	SP4_MOUSE Transcription factor Sp4 OS=Mus mus...	52	0.0000001	55.1	50	60	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0008016; P:regulation of heart contraction; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
64	Q00911	478	EGR4_RAT Early growth response protein 4 OS=R...	99	0.001	43.1	30	40	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
65	O15391	372	TYY2_HUMAN Transcription factor YY2 OS=Homo s...	52	0.002	42.4	37	54	GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
66	Q9WUF2	478	EGR4_MOUSE Early growth response protein 4 OS...	99	0.0006	43.9	30	40	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
67	Q05215	486	EGR4_HUMAN Early growth response protein 4 OS...	46	4.4	32	35	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
68	O94130	435	CREA_BOTFU DNA-binding protein creA OS=Botryo...	57	0.0000001	54.7	46	53	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
69	P08155	845	KRUH_DROME Krueppel homologous protein 1 OS=D...	26	3.1	32.3	54	62	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007552; P:metamorphosis; IMP:FlyBase.::GO:0035075; P:response to ecdysone; IMP:FlyBase.
70	P10073	491	ZSC22_HUMAN Zinc finger and SCAN domain-conta...	55	0.13	36.6	35	53	GO:0005634; C:nucleus; NAS:UniProtKB.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
71	Q6PGE4	1016	ZF316_MOUSE Zinc finger protein 316 OS=Mus mu...	55	1.2	33.9	31	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
72	Q9GL32	482	EGR4_BOVIN Early growth response protein 4 OS...	46	4.1	32	35	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
73	Q06889	387	EGR3_HUMAN Early growth response protein 3 OS...	112	0.00009	46.2	34	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0002042; P:cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.::GO:0044344; P:cellular response to fibroblast growth factor stimulus; IMP:BHF-UCL.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.::GO:0007623; P:circadian rhythm; TAS:ProtInc.::GO:0035767; P:endothelial cell chemotaxis; IMP:BHF-UCL.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74	Q8VDL9	521	GLIS2_MOUSE Zinc finger protein GLIS2 OS=Mus ...	49	0.29	35.4	41	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
75	A6NFI3	1004	ZN316_HUMAN Zinc finger protein 316 OS=Homo s...	55	0.48	35	33	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
76	Q8BKX7	478	ZN410_MOUSE Zinc finger protein 410 OS=Mus mu...	48	0.25	35.8	38	52	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
77	P43301	387	EGR3_RAT Early growth response protein 3 OS=R...	112	0.0001	46.2	34	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78	Q3SXZ3	478	ZN718_HUMAN Zinc finger protein 718 OS=Homo s...	55	8.8	30.8	33	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
79	Q10076	582	YANB_SCHPO Zinc finger protein C3H1.11 OS=Sch...	58	0.0000002	54.3	50	55	GO:0000790; C:nuclear chromatin; NAS:PomBase.
									GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IMP:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IMP:PomBase.
80	Q86VK4	478	ZN410_HUMAN Zinc finger protein 410 OS=Homo s...	48	0.27	35.8	38	52	GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
81	P43300	387	EGR3_MOUSE Early growth response protein 3 OS...	112	0.0001	46.2	34	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.::GO:0007422; P:peripheral nervous system development; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
82	P46099	358	KLF1_MOUSE Krueppel-like factor 1 OS=Mus musc...	48	6.2	31.2	38	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
83	Q98T94	492	GLIS2_XENLA Zinc finger protein GLIS2 OS=Xeno...	49	0.35	35.4	39	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
84	Q8ST83	520	PHO_DROME Polycomb protein PHO OS=Drosophila ...	55	0.0001	45.8	40	58	GO:0031011; C:Ino80 complex; IDA:FlyBase.::GO:0005704; C:polytene chromosome band; IDA:FlyBase.::GO:0005703; C:polytene chromosome puff; IDA:FlyBase.
									GO:0031490; F:chromatin DNA binding; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006342; P:chromatin silencing; NAS:UniProtKB.::GO:0048096; P:chromatin-mediated maintenance of transcription; IDA:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006265; P:DNA topological change; IDA:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
85	Q60843	354	KLF2_MOUSE Krueppel-like factor 2 OS=Mus musc...	48	5.1	31.6	38	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0043249; P:erythrocyte maturation; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
86	Q13118	480	KLF10_HUMAN Krueppel-like factor 10 OS=Homo s...	74	0.0000005	53.1	42	53	GO:0005634; C:nucleus; TAS:ProtInc.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0001501; P:skeletal system development; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
87	O35738	402	KLF12_MOUSE Krueppel-like factor 12 OS=Mus mu...	48	0.36	35	42	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
88	Q92010	448	ZF161_CHICK Zinc finger protein 161 homolog O...	55	2.2	32.7	27	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
89	Q08376	449	ZF161_MOUSE Zinc finger protein 161 OS=Mus mu...	47	2.2	32.7	32	47	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90	Q9Y4X4	402	KLF12_HUMAN Krueppel-like factor 12 OS=Homo s...	48	0.39	35	42	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
91	O43829	449	ZF161_HUMAN Zinc finger protein 161 homolog O...	57	2	33.1	28	47	GO:0005634; C:nucleus; TAS:ProtInc.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.

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