Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR066C
Length:
220
Number of sequences:
5887
Description:
YBR066C NRG2 SGDID:S000000270, Chr II from 370699-370037, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P08047    785   SP1_HUMAN Transcription factor Sp1 OS=Homo sa...520.00000007     55.5     50     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003690; F:double-stranded DNA binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
32Q90WR8    771   SP3_CHICK Transcription factor Sp3 OS=Gallus ...650.00000007     55.5     38     57GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33O59958    430   CRE1_NEUCR DNA-binding protein cre-1 OS=1257 ...690.00000002     56.6     41     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34A1C6L9    425   CREA_ASPCL Probable DNA-binding protein creA ...570.00000002     56.6     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
35O70494    783   SP3_MOUSE Transcription factor Sp3 OS=Mus mus...650.00000006     55.8     40     57GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:MGI.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IGI:MGI.::GO:0048706; P:embryonic skeletal system development; IGI:MGI.::GO:0043353; P:enucleate erythrocyte differentiation; IGI:MGI.::GO:0030851; P:granulocyte differentiation; IMP:MGI.::GO:0001889; P:liver development; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0030219; P:megakaryocyte differentiation; IGI:MGI.::GO:0030224; P:monocyte differentiation; IMP:MGI.::GO:0001779; P:natural killer cell differentiation; IMP:MGI.::GO:0001503; P:ossification; IGI:MGI.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
36O08584    283   KLF6_MOUSE Krueppel-like factor 6 OS=Mus musc...630.26     35.4     37     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37Q99612    283   KLF6_HUMAN Krueppel-like factor 6 OS=Homo sap...630.25     35.4     37     49GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030183; P:B cell differentiation; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38Q8SUR9    449   Z856_ENCCU Zinc finger C2H2 protein ECU08_056...490.00000003     56.6     49     61GO:0005622; C:intracellular; IEA:InterPro.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
39Q99JB0    301   KLF7_MOUSE Krueppel-like factor 7 OS=Mus musc...480.41     35     42     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
40B0XSK6    424   CREA_ASPFC Probable DNA-binding protein creA ...570.00000003     56.6     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41Q9P889    429   CREA_ASPOR DNA-binding protein creA OS=Asperg...570.00000003     56.6     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42B8NGC8    429   CREA_ASPFN Probable DNA-binding protein creA ...570.00000003     56.6     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43Q02447    781   SP3_HUMAN Transcription factor Sp3 OS=Homo sa...650.00000009     55.5     38     57GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.
44O89090    784   SP1_MOUSE Transcription factor Sp1 OS=Mus mus...520.00000007     55.5     50     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0035326; F:enhancer binding; IDA:MGI.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060216; P:definitive hemopoiesis; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IGI:MGI.::GO:0048706; P:embryonic skeletal system development; IGI:MGI.::GO:0043353; P:enucleate erythrocyte differentiation; IGI:MGI.::GO:0001889; P:liver development; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0030219; P:megakaryocyte differentiation; IGI:MGI.::GO:0001503; P:ossification; IGI:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
45Q01714    786   SP1_RAT Transcription factor Sp1 OS=Rattus no...520.00000007     55.8     50     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0032993; C:protein-DNA complex; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0035035; F:histone acetyltransferase binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
46Q96LW9    406   ZN323_HUMAN Zinc finger protein 323 OS=Homo s...580.21     35.8     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
47Q4X0Z3    424   CREA_ASPFU Probable DNA-binding protein creA ...570.00000003     56.6     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48Q9BZE0    524   GLIS2_HUMAN Zinc finger protein GLIS2 OS=Homo...490.19     36.2     41     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
49Q60980    344   KLF3_MOUSE Krueppel-like factor 3 OS=Mus musc...480.084     37     42     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50O94166    431   CREA_ASPAC DNA-binding protein creA OS=Asperg...570.00000003     56.2     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51P57682    345   KLF3_HUMAN Krueppel-like factor 3 OS=Homo sap...480.089     37     42     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52A1DH89    416   CREA_NEOFI Probable DNA-binding protein creA ...570.00000004     56.2     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
53Q05620    427   CREA_ASPNG DNA-binding protein creA OS=Asperg...570.00000004     56.2     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54P25490    414   TYY1_HUMAN Transcriptional repressor protein ...520.000009     49.3     38     60GO:0031011; C:Ino80 complex; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0000400; F:four-way junction DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0034644; P:cellular response to UV; IMP:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0010225; P:response to UV-C; IMP:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q00899    414   TYY1_MOUSE Transcriptional repressor protein ...520.00001     48.9     38     60GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0031519; C:PcG protein complex; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0048593; P:camera-type eye morphogenesis; IGI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051276; P:chromosome organization; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0010225; P:response to UV-C; IMP:UniProtKB.::GO:0006403; P:RNA localization; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56A2QCJ9    427   CREA_ASPNC Probable DNA-binding protein creA ...570.00000004     55.8     46     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57P57071    1507   PRD15_HUMAN PR domain zinc finger protein 15 ...470.23     36.2     47     57GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58Q9JHX2    398   SP5_MOUSE Transcription factor Sp5 OS=Mus mus...650.000001     52     35     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060349; P:bone morphogenesis; IGI:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035121; P:tail morphogenesis; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59Q6BEB4    398   SP5_HUMAN Transcription factor Sp5 OS=Homo sa...650.000001     51.6     35     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
60Q96MM3    310   ZFP42_HUMAN Zinc finger protein 42 homolog OS...530.0000007     52.4     45     58GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008585; P:female gonad development; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0007126; P:meiosis; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61O94131    420   CREA_GIBFU DNA-binding protein creA OS=monili...870.00000006     55.5     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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