Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR066C
Length:
220
Number of sequences:
5887
Description:
YBR066C NRG2 SGDID:S000000270, Chr II from 370699-370037, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151P51774    470   EGR2_RAT E3 SUMO-protein ligase EGR2 OS=Rattu...550.023     38.9     35     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007611; P:learning or memory; IEP:RGD.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IMP:RGD.
152Q6GQH4    497   EGR1A_XENLA Early growth response protein 1-A...840.0002     45.4     35     51GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
153Q8CCE9    783   E4F1_MOUSE Transcription factor E4F1 OS=Mus m...784     32.3     28     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IDA:MGI.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IMP:MGI.::GO:0009790; P:embryo development; IMP:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010564; P:regulation of cell cycle process; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0009794; P:regulation of mitotic cell cycle, embryonic; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
154P0CH99    300   Z705D_HUMAN Zinc finger protein 705D OS=Homo ...1370.000002     50.8     30     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
155P08152    470   EGR2_MOUSE E3 SUMO-protein ligase EGR2 OS=Mus...550.023     38.9     35     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035284; P:brain segmentation; IMP:MGI.::GO:0071310; P:cellular response to organic substance; IDA:MGI.::GO:0021612; P:facial nerve structural organization; IGI:MGI.::GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0042552; P:myelination; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006611; P:protein export from nucleus; IDA:UniProtKB.::GO:0030278; P:regulation of ossification; IMP:MGI.::GO:0021660; P:rhombomere 3 formation; IMP:MGI.::GO:0021666; P:rhombomere 5 formation; IMP:MGI.::GO:0007622; P:rhythmic behavior; IDA:MGI.::GO:0014037; P:Schwann cell differentiation; IMP:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
156O14901    512   KLF11_HUMAN Krueppel-like factor 11 OS=Homo s...640.000003     50.8     39     55GO:0005634; C:nucleus; TAS:ProtInc.
GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.::GO:0000115; P:regulation of transcription involved in S phase of mitotic cell cycle; IDA:BHF-UCL.
157Q6PG37    636   ZN790_HUMAN Zinc finger protein 790 OS=Homo s...550.56     34.7     35     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
158Q5E9U0    613   SP2_BOVIN Transcription factor Sp2 OS=Bos tau...480.0001     46.2     46     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
159O35739    244   KLF9_MOUSE Krueppel-like factor 9 OS=Mus musc...350.047     37.7     37     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
160Q08427    421   EGR2_XENLA Early growth response protein 2 OS...790.003     41.6     34     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
161P18146    543   EGR1_HUMAN Early growth response protein 1 OS...1140.00006     47     32     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0035035; F:histone acetyltransferase binding; IPI:BHF-UCL.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.::GO:0072110; P:glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0033233; P:regulation of protein sumoylation; IDA:BHF-UCL.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
162Q19A40    323   KLF14_PANTR Krueppel-like factor 14 OS=Pan tr...480.0003     44.3     48     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
163Q14V87    323   KLF14_GORGO Krueppel-like factor 14 OS=Gorill...480.0003     44.3     48     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
164P08046    533   EGR1_MOUSE Early growth response protein 1 OS...1140.00008     46.6     32     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030509; P:BMP signaling pathway; IDA:MGI.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.::GO:0072110; P:glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0032868; P:response to insulin stimulus; IDA:UniProtKB.::GO:0030217; P:T cell differentiation; IMP:MGI.
165Q02086    613   SP2_HUMAN Transcription factor Sp2 OS=Homo sa...480.0001     46.2     46     56GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006955; P:immune response; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
166P0CJ78    1059   ZN865_HUMAN Zinc finger protein 865 OS=Homo s...554.7     32     31     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
167Q9D2H6    612   SP2_MOUSE Transcription factor Sp2 OS=Mus mus...520.00008     46.6     44     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
168Q8CJ78    1038   ZN628_MOUSE Zinc finger protein 628 OS=Mus mu...671.6     33.5     34     45GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
169Q9UJW7    825   ZN229_HUMAN Zinc finger protein 229 OS=Homo s...550.66     34.7     35     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
170Q14590    738   ZN235_HUMAN Zinc finger protein 235 OS=Homo s...552.2     33.1     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
171P17022    549   ZNF18_HUMAN Zinc finger protein 18 OS=Homo sa...553.5     32.3     35     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
172O73693    193   EGR1_TAEGU Early growth response protein 1 OS...520.0008     42.7     44     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:AgBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
173A1XSY8    471   EGR2_PIG E3 SUMO-protein ligase EGR2 OS=Sus s...550.022     38.9     35     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006611; P:protein export from nucleus; ISS:UniProtKB.
174Q8NHY6    868   ZFP28_HUMAN Zinc finger protein 28 homolog OS...1049.5     31.2     23     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
175Q8TD94    323   KLF14_HUMAN Krueppel-like factor 14 OS=Homo s...480.0004     43.9     48     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
176P10069    432   BRLA_EMENI Regulatory protein brlA OS=194 / M...560.000003     50.8     45     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048315; P:conidium formation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
177Q9BXK1    252   KLF16_HUMAN Krueppel-like factor 16 OS=Homo s...480.0006     43.5     46     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
178Q8BIF9    381   ZN787_MOUSE Zinc finger protein 787 OS=Mus mu...490.42     35     35     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
179P08154    508   EGR1_RAT Early growth response protein 1 OS=R...570.000003     50.8     40     60GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:RGD.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:RGD.::GO:0008134; F:transcription factor binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0035690; P:cellular response to drug; IEP:RGD.::GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0071504; P:cellular response to heparin; IDA:UniProtKB.::GO:0071455; P:cellular response to hyperoxia; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071317; P:cellular response to isoquinoline alkaloid; IEP:RGD.::GO:0071260; P:cellular response to mechanical stimulus; IEP:RGD.::GO:0071506; P:cellular response to mycophenolic acid; IDA:UniProtKB.::GO:0071383; P:cellular response to steroid hormone stimulus; IEP:RGD.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0072110; P:glomerular mesangial cell proliferation; IMP:UniProtKB.::GO:0007611; P:learning or memory; IMP:RGD.::GO:0060291; P:long-term synaptic potentiation; IEP:RGD.::GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; IMP:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:RGD.::GO:0001975; P:response to amphetamine; IEP:RGD.::GO:0034465; P:response to carbon monoxide; IEP:RGD.::GO:0042220; P:response to cocaine; IEP:RGD.::GO:0051602; P:response to electrical stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0071873; P:response to norepinephrine stimulus; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.
180Q293Q2    550   SQZ_DROPS Zinc finger protein squeeze OS=Dros...550.000003     50.8     44     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
181Q8VCZ7    619   ZBT7C_MOUSE Zinc finger and BTB domain-contai...830.046     38.1     29     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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