rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | O94822 | 1766 | LTN1_HUMAN E3 ubiquitin-protein ligase lister... | 60 | 0.34 | 35 | 32 | 48 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 272 | Q99MP8 | 591 | BRAP_MOUSE BRCA1-associated protein OS=Mus mu... | 61 | 0.34 | 35 | 34 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 273 | Q9H6Y7 | 350 | RN167_HUMAN E3 ubiquitin-protein ligase RNF16... | 67 | 0.35 | 34.7 | 37 | 54 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045786; P:negative regulation of cell cycle; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 274 | Q9NS56 | 1045 | TOPRS_HUMAN E3 ubiquitin-protein ligase Topor... | 70 | 0.38 | 34.7 | 30 | 40 | GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0003823; F:antigen binding; IPI:UniProtKB.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0044547; F:DNA topoisomerase binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:UniProtKB.::GO:0051457; P:maintenance of protein location in nucleus; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; NAS:UniProtKB. | 275 | Q80Z37 | 1033 | TOPRS_MOUSE E3 ubiquitin-protein ligase Topor... | 91 | 0.39 | 34.7 | 27 | 37 | GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0019789; F:SUMO ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:MGI.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IDA:MGI. | 276 | Q7TPH6 | 4711 | MYCB2_MOUSE Probable E3 ubiquitin-protein lig... | 84 | 0.43 | 34.7 | 30 | 45 | GO:0030424; C:axon; IDA:MGI.::GO:0015630; C:microtubule cytoskeleton; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021785; P:branchiomotor neuron axon guidance; IMP:MGI.::GO:0021952; P:central nervous system projection neuron axonogenesis; IMP:MGI.::GO:0051493; P:regulation of cytoskeleton organization; IMP:MGI.::GO:0032880; P:regulation of protein localization; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 277 | O75592 | 4640 | MYCB2_HUMAN Probable E3 ubiquitin-protein lig... | 100 | 0.45 | 34.7 | 31 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 278 | Q7ZX20 | 540 | RNF8A_XENLA E3 ubiquitin-protein ligase RNF8-... | 49 | 0.48 | 34.3 | 33 | 49 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 279 | Q7Z569 | 592 | BRAP_HUMAN BRCA1-associated protein OS=Homo s... | 61 | 0.49 | 34.3 | 34 | 49 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000165; P:MAPK cascade; IDA:MGI.::GO:0009968; P:negative regulation of signal transduction; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IDA:MGI. | 280 | Q91XF4 | 347 | RN167_MOUSE E3 ubiquitin-protein ligase RNF16... | 67 | 0.52 | 34.3 | 37 | 54 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 281 | D2HWM5 | 773 | RFWD3_AILME E3 ubiquitin-protein ligase RFWD3... | 85 | 0.54 | 34.3 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 282 | Q8HXH0 | 718 | LONF3_MACFA LON peptidase N-terminal domain a... | 69 | 0.57 | 34.3 | 35 | 48 | | | | | | | | | | | GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 283 | Q496Y0 | 759 | LONF3_HUMAN LON peptidase N-terminal domain a... | 69 | 0.61 | 34.3 | 35 | 48 | | | | | | | | | | | GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 284 | Q7ZW16 | 318 | RNF41_DANRE E3 ubiquitin-protein ligase NRDP1... | 48 | 0.62 | 33.9 | 35 | 50 | | | | | | | | | | | GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030318; P:melanocyte differentiation; IMP:ZFIN.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 285 | Q5XIL0 | 349 | RN167_RAT E3 ubiquitin-protein ligase RNF167 ... | 67 | 0.73 | 33.9 | 36 | 54 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 286 | Q2XNS1 | 231 | RN141_CANFA RING finger protein 141 OS=Canis ... | 66 | 0.74 | 33.5 | 30 | 41 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 287 | Q8NEG5 | 633 | ZSWM2_HUMAN E3 ubiquitin-protein ligase ZSWIM... | 74 | 0.74 | 33.9 | 27 | 47 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 288 | Q32L15 | 230 | RN141_BOVIN RING finger protein 141 OS=Bos ta... | 66 | 0.75 | 33.5 | 30 | 41 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 289 | Q9D4H7 | 753 | LONF3_MOUSE LON peptidase N-terminal domain a... | 49 | 0.75 | 33.9 | 37 | 51 | | | | | | | | | | | GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 290 | Q5R7K8 | 230 | RN141_PONAB RING finger protein 141 OS=Pongo ... | 66 | 0.79 | 33.5 | 30 | 41 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 291 | Q8WVD5 | 230 | RN141_HUMAN RING finger protein 141 OS=Homo s... | 66 | 0.79 | 33.5 | 30 | 41 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 292 | Q6IV57 | 230 | RN141_RAT RING finger protein 141 OS=Rattus n... | 66 | 0.8 | 33.5 | 30 | 41 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 293 | Q86HL5 | 468 | HMCSB_DICDI Hydroxymethylglutaryl-CoA synthas... | 46 | 0.82 | 33.5 | 39 | 59 | | | | | | | | | | | GO:0004421; F:hydroxymethylglutaryl-CoA synthase activity; IEA:EC. | | | | | | | | | | GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 294 | Q99MB7 | 230 | RN141_MOUSE RING finger protein 141 OS=Mus mu... | 66 | 0.84 | 33.1 | 30 | 41 | | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IDA:MGI. | 295 | B1AUE5 | 324 | PEX10_MOUSE Peroxisome biogenesis factor 10 O... | 33 | 0.84 | 33.5 | 36 | 58 | GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro. | 296 | A5WW08 | 637 | CHFR_DANRE E3 ubiquitin-protein ligase CHFR O... | 67 | 0.86 | 33.5 | 30 | 49 | GO:0016605; C:PML body; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 297 | Q09463 | 235 | RNF5_CAEEL RING finger protein 5 OS=Caenorhab... | 57 | 0.88 | 33.1 | 33 | 51 | GO:0030054; C:cell junction; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:WormBase.::GO:0055002; P:striated muscle cell development; IMP:WormBase. | 298 | Q12161 | 406 | PSH1_YEAST RING finger protein PSH1 OS=Saccha... | 52 | 0.88 | 33.5 | 31 | 48 | GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD. | 299 | Q5UQ40 | 1297 | UBC4_MIMIV Probable bifunctional E2/E3 enzyme... | 64 | 0.88 | 33.9 | 30 | 41 | GO:0000151; C:ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 300 | P29836 | 676 | ICP0_BHV1K E3 ubiquitin-protein ligase ICP0 O... | 27 | 0.97 | 33.5 | 48 | 56 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 301 | P53804 | 2025 | TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 O... | 78 | 1 | 33.5 | 24 | 37 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB. |