Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR060C
Length:
620
Number of sequences:
5887
Description:
YBR060C ORC2 SGDID:S000000264, Chr II from 362514-360652, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32833    620   ORC2_YEAST Origin recognition complex subunit...6200     1283     100     100GO:0031261; C:DNA replication preinitiation complex; IDA:SGD.::GO:0005664; C:nuclear origin of replication recognition complex; IMP:SGD.::GO:0005656; C:pre-replicative complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030466; P:chromatin silencing at silent mating-type cassette; IDA:SGD.::GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0051568; P:histone H3-K4 methylation; IMP:SGD.::GO:0006267; P:pre-replicative complex assembly; IDA:SGD.
2Q09142    535   ORC2_SCHPO Origin recognition complex subunit...3898e-44     168     29     49GO:0032153; C:cell division site; IDA:PomBase.::GO:0031261; C:DNA replication preinitiation complex; IC:PomBase.::GO:0005664; C:nuclear origin of replication recognition complex; IDA:UniProtKB.::GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0005656; C:pre-replicative complex; IC:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0003688; F:DNA replication origin binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006270; P:DNA-dependent DNA replication initiation; NAS:UniProtKB.
3Q24168    618   ORC2_DROME Origin recognition complex subunit...3992e-37     150     27     47GO:0005723; C:alpha-heterochromatin; IDA:FlyBase.::GO:0005664; C:nuclear origin of replication recognition complex; IDA:FlyBase.
GO:0003682; F:chromatin binding; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0006270; P:DNA-dependent DNA replication initiation; IDA:FlyBase.::GO:0007307; P:eggshell chorion gene amplification; IMP:FlyBase.::GO:0007076; P:mitotic chromosome condensation; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
4A6QNM3    577   ORC2_BOVIN Origin recognition complex subunit...3133e-33     137     27     52GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
5Q60862    576   ORC2_MOUSE Origin recognition complex subunit...3254e-33     137     26     51GO:0000939; C:condensed chromosome inner kinetochore; IDA:MGI.::GO:0000792; C:heterochromatin; IDA:MGI.::GO:0005664; C:nuclear origin of replication recognition complex; IDA:MGI.
GO:0003688; F:DNA replication origin binding; IDA:MGI.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
6Q13416    577   ORC2_HUMAN Origin recognition complex subunit...3187e-33     136     26     51GO:0005664; C:nuclear origin of replication recognition complex; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003688; F:DNA replication origin binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000075; P:cell cycle checkpoint; TAS:Reactome.::GO:0006270; P:DNA-dependent DNA replication initiation; TAS:ProtInc.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
7Q75PQ8    576   ORC2_RAT Origin recognition complex subunit 2...3185e-32     134     26     50
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
8Q38899    363   ORC2_ARATH Origin recognition complex subunit...3781e-31     130     27     46
GO:0005515; F:protein binding; IPI:IntAct.
9Q91628    558   ORC2_XENLA Origin recognition complex subunit...3281e-29     127     26     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
10Q55CU7    391   ORC2_DICDI Origin recognition complex subunit...3355e-16     84     24     45GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0005634; C:nucleus; IDA:dictyBase.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0003688; F:DNA replication origin binding; ISS:dictyBase.
GO:0006270; P:DNA-dependent DNA replication initiation; ISS:dictyBase.
11Q21037    430   ORC2_CAEEL Origin recognition complex subunit...3230.00000000000005     78.2     24     43GO:0000228; C:nuclear chromosome; IDA:WormBase.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.
12O18473    576   ECR_HELVI Ecdysone receptor OS=Heliothis vire...671.3     35.8     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004884; F:ecdysteroid hormone receptor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0005496; F:steroid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
13A3DHM4    397   METK_CLOTH S-adenosylmethionine synthase OS=C...721.3     35.4     35     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004478; F:methionine adenosyltransferase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006556; P:S-adenosylmethionine biosynthetic process; IEA:InterPro.
14Q8AVN9    524   ZN346_XENLA Zinc finger protein 346 OS=Xenopu...1293     34.7     21     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
15Q49A26    553   GLYR1_HUMAN Putative oxidoreductase GLYR1 OS=...764.1     34.3     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
16Q5R7T2    553   GLYR1_PONAB Putative oxidoreductase GLYR1 OS=...764.1     34.3     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
17Q4P2W8    798   DOT1_USTMA Histone-lysine N-methyltransferase...936.4     33.5     26     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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