Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR059C
Length:
1108
Number of sequences:
5887
Description:
YBR059C AKL1 SGDID:S000000263, Chr II from 360187-356861, Genome Release 64-1-1, reverse complement, Verified ORF, "Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
691Q91YA2    424   KPSH1_MOUSE Serine/threonine-protein kinase H...2500.000000008     62.8     27     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
692Q9LMP1    732   WAK2_ARATH Wall-associated receptor kinase 2 ...1650.000000008     63.5     28     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009992; P:cellular water homeostasis; IDA:TAIR.::GO:0009311; P:oligosaccharide metabolic process; IMP:TAIR.::GO:0009751; P:response to salicylic acid stimulus; IDA:TAIR.::GO:0009826; P:unidimensional cell growth; IMP:TAIR.
693P43637    560   TOS3_YEAST Serine/threonine-protein kinase TO...2040.000000008     63.2     25     47GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0006006; P:glucose metabolic process; IMP:SGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
694Q8G6P9    690   PKNB_BIFLO Probable serine/threonine-protein ...2410.000000009     63.2     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
695D7UQM5    407   AURK_ASTPE Aurora kinase OS=Asterina pectinif...2810.000000009     62.8     27     44GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
696Q9LK03    717   PERK2_ARATH Proline-rich receptor-like protei...2350.000000009     63.5     25     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
697Q07832    603   PLK1_MOUSE Serine/threonine-protein kinase PL...2060.000000009     63.2     27     45GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
698D3ZBE5    302   NEK7_RAT Serine/threonine-protein kinase Nek7...2290.000000009     62     28     42GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
699Q8C1R0    372   TSSK5_MOUSE Testis-specific serine/threonine-...2270.000000009     62.4     25     48
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
700O64639    683   Y2559_ARATH Receptor-like serine/threonine-pr...1650.000000009     63.2     28     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
701A8X0C4    649   PAR4_CAEBR Serine/threonine-protein kinase pa...2430.000000009     63.2     26     46GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
702Q54PK9    908   PDPKB_DICDI 3-phosphoinositide-dependent prot...2520.000000009     63.5     26     44
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
703Q9VXE5    639   PAKM_DROME Serine/threonine-protein kinase PA...2300.000000009     63.2     25     45GO:0005913; C:cell-cell adherens junction; IDA:FlyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:FlyBase.
GO:0000187; P:activation of MAPK activity; TAS:UniProtKB.::GO:0001751; P:compound eye photoreceptor cell differentiation; IMP:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:UniProtKB.::GO:0045792; P:negative regulation of cell size; IMP:FlyBase.::GO:0045315; P:positive regulation of compound eye photoreceptor development; IMP:UniProtKB.
704O64780    814   Y1614_ARATH G-type lectin S-receptor-like ser...2360.000000009     63.2     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0044459; C:plasma membrane part; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0048544; P:recognition of pollen; IEA:InterPro.
705Q64595    762   KGP2_RAT cGMP-dependent protein kinase 2 OS=R...2840.00000001     63.2     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC.
706Q80YE7    1442   DAPK1_MOUSE Death-associated protein kinase 1...1830.00000001     63.5     25     52GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IMP:UniProtKB.
707P92958    512   KIN11_ARATH SNF1-related protein kinase catal...2330.00000001     62.8     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
708Q86V86    326   PIM3_HUMAN Serine/threonine-protein kinase pi...2290.00000001     62     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
709D0N4E2    399   PKZ1_PHYIT Serine/threonine-protein kinase PK...2790.00000001     62.4     27     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
710P25323    295   MYLKA_DICDI Myosin light chain kinase A OS=Di...2090.00000001     61.6     27     50GO:0005737; C:cytoplasm; IDA:dictyBase.
GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IDA:dictyBase.
GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0019934; P:cGMP-mediated signaling; IDA:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.
711Q5B4Z3    1346   SEPH_EMENI Cytokinesis protein sepH OS=194 / ...2890.00000001     63.5     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
712P24723    683   KPCL_HUMAN Protein kinase C eta type OS=Homo ...2850.00000001     63.2     25     43GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; IMP:UniProtKB.
713O14578    2027   CTRO_HUMAN Citron Rho-interacting kinase OS=H...1570.00000001     63.5     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0033205; P:cell cycle cytokinesis; IMP:UniProtKB.::GO:0048699; P:generation of neurons; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007067; P:mitosis; ISS:UniProtKB.
714Q54RB7    527   SHKA_DICDI Dual specificity protein kinase sh...2930.00000001     62.8     27     45GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051219; F:phosphoprotein binding; ISS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase.
GO:0030036; P:actin cytoskeleton organization; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0009968; P:negative regulation of signal transduction; IMP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.
715O08605    427   MKNK1_MOUSE MAP kinase-interacting serine/thr...2630.00000001     62.4     25     44
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; NAS:UniProtKB.
716Q8VYA3    769   WAKLJ_ARATH Wall-associated receptor kinase-l...1950.00000001     63.2     27     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004383; F:guanylate cyclase activity; IDA:TAIR.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006952; P:defense response; IEP:TAIR.::GO:0009617; P:response to bacterium; IEP:TAIR.::GO:0009620; P:response to fungus; IEP:TAIR.::GO:0009751; P:response to salicylic acid stimulus; IEP:TAIR.
717Q25378    658   KPC1_LYTPI Protein kinase C OS=Lytechinus pic...1430.00000001     62.8     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
718Q93VK0    278   PPCK2_ARATH Phosphoenolpyruvate carboxylase k...2510.00000001     61.2     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0016036; P:cellular response to phosphate starvation; IEP:TAIR.::GO:0046898; P:response to cycloheximide; IDA:UniProtKB.::GO:0009416; P:response to light stimulus; IDA:UniProtKB.
719Q6NW76    320   AURKB_DANRE Aurora kinase B OS=Danio rerio (Z...2320.00000001     61.6     26     44GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007059; P:chromosome segregation; IMP:ZFIN.::GO:0000910; P:cytokinesis; IMP:ZFIN.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
720P09216    737   KPCE_RAT Protein kinase C epsilon type OS=Rat...2820.00000001     62.8     23     43GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:RGD.::GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0003785; F:actin monomer binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0017124; F:SH3 domain binding; IPI:RGD.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0010763; P:positive regulation of fibroblast migration; ISS:UniProtKB.::GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.::GO:0035669; P:TRAM-dependent toll-like receptor 4 signaling pathway; ISS:UniProtKB.
721P42684    1182   ABL2_HUMAN Abelson tyrosine-protein kinase 2 ...2320.00000001     63.2     26     41GO:0015629; C:actin cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0051015; F:actin filament binding; TAS:UniProtKB.::GO:0003785; F:actin monomer binding; TAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
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