UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR058C

Length:

80

Number of sequences:

5887

Description:

YBR058C-A TSC3 SGDID:S000007521, Chr II from 356566-356324, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	Q6GLV4	290	UBX1B_XENLA UBX domain-containing protein 1-B...	49	0.00000004	59.3	49	69	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
62	B4LG38	1214	UBP36_DROVI Ubiquitin carboxyl-terminal hydro...	243	0.00000004	60.8	21	44	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
63	Q91W36	520	UBP3_MOUSE Ubiquitin carboxyl-terminal hydrol...	60	0.012	42.7	33	45
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
64	Q5R5Z6	913	UBP20_PONAB Ubiquitin carboxyl-terminal hydro...	61	0.37	38.1	28	51	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
65	O74442	457	UBP16_SCHPO Probable ubiquitin carboxyl-termi...	250	0.00000004	60.1	23	43	GO:0005730; C:nucleolus; IDA:PomBase.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
									GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
66	E2RK09	981	UBP37_CANFA Ubiquitin carboxyl-terminal hydro...	62	0.002	45.4	35	53
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
67	Q9Y6I4	520	UBP3_HUMAN Ubiquitin carboxyl-terminal hydrol...	101	0.007	43.5	28	40	GO:0000790; C:nuclear chromatin; IDA:UniProtKB.
									GO:0042393; F:histone binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IMP:UniProtKB.::GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
68	Q09738	449	UBP8_SCHPO Probable ubiquitin carboxyl-termin...	59	0.41	37.7	31	53	GO:0000124; C:SAGA complex; IDA:PomBase.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0016573; P:histone acetylation; IC:PomBase.::GO:0035616; P:histone H2B conserved C-terminal lysine deubiquitination; ISS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
69	F1N5V1	981	UBP37_BOVIN Ubiquitin carboxyl-terminal hydro...	62	0.002	45.4	35	53
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
70	Q754R5	848	UBP4_ASHGO Ubiquitin carboxyl-terminal hydrol...	307	0.00000008	59.7	22	39	GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
71	B4MLR8	1311	UBP36_DROWI Ubiquitin carboxyl-terminal hydro...	280	0.00000009	59.7	24	43	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
72	F1SRY5	982	UBP37_PIG Ubiquitin carboxyl-terminal hydrola...	62	0.002	45.8	35	53
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
73	Q9Y2K6	914	UBP20_HUMAN Ubiquitin carboxyl-terminal hydro...	61	0.36	38.1	28	51	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.::GO:0001664; F:G-protein coupled receptor binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
74	B4HUI5	1059	UBP36_DROSE Ubiquitin carboxyl-terminal hydro...	205	0.0000001	59.3	23	45	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
75	Q9FIQ1	732	UBP21_ARATH Ubiquitin carboxyl-terminal hydro...	258	0.0000001	58.9	26	42
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
76	A7TGY3	882	UBP4_VANPO Ubiquitin carboxyl-terminal hydrol...	313	0.0000001	58.9	24	38	GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
77	Q70CQ2	3546	UBP34_HUMAN Ubiquitin carboxyl-terminal hydro...	269	0.0000002	59.3	24	41
									GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
78	Q9UPT9	525	UBP22_HUMAN Ubiquitin carboxyl-terminal hydro...	62	0.15	39.3	37	60	GO:0000124; C:SAGA complex; IDA:UniProtKB.
									GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; NAS:UniProtKB.::GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IDA:GOC.::GO:0016574; P:histone ubiquitination; IDA:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
79	A6ZY34	926	UBP4_YEAS7 Ubiquitin carboxyl-terminal hydrol...	91	0.01	43.1	32	49	GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
80	Q99K46	921	UBP11_MOUSE Ubiquitin carboxyl-terminal hydro...	182	0.0000003	58.2	26	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
81	Q8R5H1	981	UBP15_MOUSE Ubiquitin carboxyl-terminal hydro...	186	0.0000003	57.8	27	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
82	Q9Y4E8	981	UBP15_HUMAN Ubiquitin carboxyl-terminal hydro...	186	0.0000003	57.8	27	42
									GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
83	Q8C6M1	916	UBP20_MOUSE Ubiquitin carboxyl-terminal hydro...	66	2.6	35.4	26	47	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
84	Q6DCJ1	523	UB22B_XENLA Ubiquitin carboxyl-terminal hydro...	79	0.14	39.3	35	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
85	Q8C0R0	979	UBP37_MOUSE Ubiquitin carboxyl-terminal hydro...	62	0.003	45.1	35	53
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
86	Q4R6D3	373	UBP50_MACFA Putative ubiquitin carboxyl-termi...	248	0.0000004	56.6	22	41
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
87	P39967	754	UBP9_YEAST Ubiquitin carboxyl-terminal hydrol...	63	0.047	40.8	33	52	GO:0005737; C:cytoplasm; IC:SGD.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
									GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
88	A1A5G2	1354	UBP47_XENTR Ubiquitin carboxyl-terminal hydro...	276	0.0000004	57.4	23	42	GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
89	Q20296	955	HDA6_CAEEL Histone deacetylase 6 OS=Caenorhab...	107	0.0000005	57.4	31	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90	Q6ZQ93	3582	UBP34_MOUSE Ubiquitin carboxyl-terminal hydro...	269	0.0000005	57.4	25	41
									GO:0005488; F:binding; IEA:InterPro.::GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
91	Q6GNI6	523	UB22A_XENLA Ubiquitin carboxyl-terminal hydro...	79	0.099	39.7	35	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.

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