Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR058C
Length:
80
Number of sequences:
5887
Description:
YBR058C-A TSC3 SGDID:S000007521, Chr II from 356566-356324, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q9Z2V5    1149   HDAC6_MOUSE Histone deacetylase 6 OS=Mus musc...1010.21     38.9     27     45GO:0005881; C:cytoplasmic microtubule; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0048487; F:beta-tubulin binding; IDA:MGI.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0042903; F:tubulin deacetylase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070842; P:aggresome assembly; IGI:MGI.::GO:0071218; P:cellular response to misfolded protein; IMP:MGI.::GO:0070846; P:Hsp90 deacetylation; IMP:MGI.::GO:0007026; P:negative regulation of microtubule depolymerization; IDA:MGI.::GO:0000209; P:protein polyubiquitination; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0090042; P:tubulin deacetylation; IDA:UniProtKB.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:MGI.
242O96612    451   UBPB_DICDI Ubiquitin hydrolase B OS=Dictyoste...650.25     38.5     25     46
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0016579; P:protein deubiquitination; IDA:dictyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
243Q0CT11    768   CREB_ASPTN Probable ubiquitin carboxyl-termin...1710.31     38.1     24     37
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
244A6NCW7    530   U17L4_HUMAN Inactive ubiquitin carboxyl-termi...610.32     38.1     26     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
245Q8VDI7    409   UBAC1_MOUSE Ubiquitin-associated domain-conta...480.32     37.7     33     56
246Q5XIR9    409   UBAC1_RAT Ubiquitin-associated domain-contain...480.32     37.7     33     56
247Q2KJ72    565   UBP21_BOVIN Ubiquitin carboxyl-terminal hydro...590.34     38.1     34     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
248Q9UK80    565   UBP21_HUMAN Ubiquitin carboxyl-terminal hydro...590.35     38.1     34     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
249P55824    2778   FAF_DROME Probable ubiquitin carboxyl-termina...1480.36     38.1     23     41GO:0005737; C:cytoplasm; IDA:FlyBase.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:FlyBase.
GO:0007349; P:cellularization; IMP:FlyBase.::GO:0009790; P:embryo development; IMP:FlyBase.::GO:0006897; P:endocytosis; NAS:FlyBase.::GO:0008354; P:germ cell migration; TAS:FlyBase.::GO:0008583; P:mystery cell differentiation; IMP:FlyBase.::GO:0045861; P:negative regulation of proteolysis; NAS:FlyBase.::GO:0007097; P:nuclear migration; IMP:FlyBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:FlyBase.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IGI:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
250B2GUX4    565   UBP21_RAT Ubiquitin carboxyl-terminal hydrola...590.37     37.7     34     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
251Q9QZL6    566   UBP21_MOUSE Ubiquitin carboxyl-terminal hydro...590.39     37.7     34     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
252Q5RE63    375   UBP18_PONAB Ubl carboxyl-terminal hydrolase 1...2500.44     37.4     22     40
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
253Q8GY23    3681   UPL1_ARATH E3 ubiquitin-protein ligase UPL1 O...660.46     37.7     30     48GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
254Q70CQ4    1352   UBP31_HUMAN Ubiquitin carboxyl-terminal hydro...2240.55     37.7     22     38
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
255P35822    1457   PTPRK_MOUSE Receptor-type tyrosine-protein ph...660.58     37.4     35     47GO:0030424; C:axon; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
256Q15262    1439   PTPRK_HUMAN Receptor-type tyrosine-protein ph...660.61     37.4     35     47GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031256; C:leading edge membrane; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.
GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
257Q9SCJ9    1067   UBP26_ARATH Ubiquitin carboxyl-terminal hydro...310.76     37     48     68GO:0005730; C:nucleolus; IDA:TAIR.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0048316; P:seed development; IMP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
258B1WBD7    840   UBP20_XENLA Ubiquitin carboxyl-terminal hydro...610.81     37     30     49GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
259O76387    316   PTH2_CAEEL Probable peptidyl-tRNA hydrolase 2...901.1     35.8     27     47
GO:0004045; F:aminoacyl-tRNA hydrolase activity; IEA:EC.
GO:0040010; P:positive regulation of growth rate; IMP:WormBase.
260Q9WTV6    368   UBP18_MOUSE Ubl carboxyl-terminal hydrolase 1...2384.4     34.3     20     38
GO:0019785; F:ISG15-specific protease activity; IMP:MGI.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0032020; P:ISG15-protein conjugation; IMP:MGI.::GO:0035634; P:response to stilbenoid; IEP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
261P18248    261   PCNA_XENLA Proliferating cell nuclear antigen...761.3     35.4     32     46GO:0043626; C:PCNA complex; IEA:InterPro.::GO:0070557; C:PCNA-p21 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006275; P:regulation of DNA replication; IEA:InterPro.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.
262Q7ZXR7    805   UB10B_XENLA Ubiquitin carboxyl-terminal hydro...701.4     36.2     23     47GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042980; F:cystic fibrosis transmembrane conductance regulator binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
263Q9FPS9    924   UBP15_ARATH Ubiquitin carboxyl-terminal hydro...2611.5     36.2     23     38GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; IMP:TAIR.::GO:0009908; P:flower development; IMP:TAIR.::GO:0010154; P:fruit development; IMP:TAIR.::GO:0048366; P:leaf development; IMP:TAIR.::GO:0016579; P:protein deubiquitination; IDA:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
264Q15751    4861   HERC1_HUMAN Probable E3 ubiquitin-protein lig...2151.6     36.2     24     37GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc.
GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
265A9A1F7    272   ASPD_NITMS Probable L-aspartate dehydrogenase...1082.5     34.7     27     42
GO:0033735; F:aspartate dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.::GO:0006742; P:NADP catabolic process; IEA:InterPro.
266A6L5I2    496   SYP_BACV8 Proline--tRNA ligase OS=Bacteroides...662.7     35     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004827; F:proline-tRNA ligase activity; IEA:EC.
GO:0006433; P:prolyl-tRNA aminoacylation; IEA:InterPro.
267Q4VSI4    1103   UBP7_RAT Ubiquitin carboxyl-terminal hydrolas...613.6     35     38     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:RGD.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
268Q6U7I1    1101   UBP7_CHICK Ubiquitin carboxyl-terminal hydrol...613.7     34.7     38     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
269Q6A4J8    1103   UBP7_MOUSE Ubiquitin carboxyl-terminal hydrol...613.7     34.7     38     54GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
270Q93009    1102   UBP7_HUMAN Ubiquitin carboxyl-terminal hydrol...613.8     34.7     38     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
271Q3LFD5    358   UBP41_HUMAN Putative ubiquitin carboxyl-termi...514.4     34.3     43     55
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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