UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR058C

Length:

80

Number of sequences:

5887

Description:

YBR058C-A TSC3 SGDID:S000007521, Chr II from 356566-356324, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
121	O60079	979	UBP12_SCHPO Probable ubiquitin carboxyl-termi...	293	0.00001	52.8	25	38	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
									GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
122	Q0V9G5	652	UBP44_XENTR Ubiquitin carboxyl-terminal hydro...	68	0.00001	52.4	37	60	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051322; P:anaphase; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
123	P38187	747	UBP13_YEAST Ubiquitin carboxyl-terminal hydro...	160	0.00002	52.4	26	47
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
124	P51784	963	UBP11_HUMAN Ubiquitin carboxyl-terminal hydro...	194	0.00002	52.4	27	39	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
125	A0JM59	884	UBP20_XENTR Ubiquitin carboxyl-terminal hydro...	61	0.69	37.4	30	49	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
126	A6NNY8	438	UBP27_HUMAN Ubiquitin carboxyl-terminal hydro...	264	0.00002	51.6	22	37
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
127	P40453	1071	UBP7_YEAST Ubiquitin carboxyl-terminal hydrol...	181	0.00002	52	29	42	GO:0005737; C:cytoplasm; IC:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
									GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
128	A2XDG4	1079	UBP26_ORYSI Ubiquitin carboxyl-terminal hydro...	46	0.76	37	35	65	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
129	A3AF13	1079	UBP26_ORYSJ Ubiquitin carboxyl-terminal hydro...	46	0.76	37	35	65	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
130	Q5U349	618	UBP2_RAT Ubiquitin carboxyl-terminal hydrolas...	192	0.00002	51.6	25	40	GO:0005813; C:centrosome; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0048642; P:negative regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0048643; P:positive regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
131	Q6NTR6	690	UP44A_XENLA Ubiquitin carboxyl-terminal hydro...	61	0.027	41.6	38	48	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051322; P:anaphase; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
132	Q5ZM45	1033	UBP48_CHICK Ubiquitin carboxyl-terminal hydro...	41	0.84	37	37	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
133	Q5XGZ2	690	UP44B_XENLA Ubiquitin carboxyl-terminal hydro...	61	0.031	41.6	38	48	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051322; P:anaphase; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
134	Q99MX1	835	UBP26_MOUSE Ubiquitin carboxyl-terminal hydro...	262	0.00003	51.6	23	42	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
135	Q9SB51	1008	UBP16_ARATH Ubiquitin carboxyl-terminal hydro...	71	0.001	46.2	35	49	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0008283; P:cell proliferation; IGI:TAIR.::GO:0009908; P:flower development; IGI:TAIR.::GO:0048366; P:leaf development; IGI:TAIR.::GO:0048364; P:root development; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
136	P39944	805	UBP5_YEAST Ubiquitin carboxyl-terminal hydrol...	254	0.00003	51.6	23	40	GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
									GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
137	A6QR55	963	UBP4_BOVIN Ubiquitin carboxyl-terminal hydrol...	186	0.00003	51.2	26	42	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
138	Q95QN6	590	YQOE_CAEEL Uncharacterized RING finger protei...	74	0.00003	50.8	35	50
									GO:0008270; F:zinc ion binding; IEA:InterPro.
139	P35123	962	UBP4_MOUSE Ubiquitin carboxyl-terminal hydrol...	186	0.00004	50.8	25	42	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
140	Q9C585	871	UBP8_ARATH Ubiquitin carboxyl-terminal hydrol...	243	0.00005	50.8	26	41
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
141	Q13107	963	UBP4_HUMAN Ubiquitin carboxyl-terminal hydrol...	186	0.00005	50.8	26	42	GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0031685; F:adenosine receptor binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
142	Q99MP8	591	BRAP_MOUSE BRCA1-associated protein OS=Mus mu...	73	0.00005	50.4	37	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
143	Q5RCD3	963	UBP4_PONAB Ubiquitin carboxyl-terminal hydrol...	186	0.00005	50.8	26	42	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
144	Q7Z569	592	BRAP_HUMAN BRCA1-associated protein OS=Homo s...	73	0.00005	50.4	37	49	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI.
									GO:0008139; F:nuclear localization sequence binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000165; P:MAPK cascade; IDA:MGI.::GO:0009968; P:negative regulation of signal transduction; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.
145	Q9D9M2	370	UBP12_MOUSE Ubiquitin carboxyl-terminal hydro...	73	1.3	35.8	33	52
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
146	Q5M981	370	UB12B_XENLA Ubiquitin carboxyl-terminal hydro...	73	1.4	35.8	33	52
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
147	D2HBJ8	711	UBP44_AILME Ubiquitin carboxyl-terminal hydro...	61	0.021	42	38	48	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051322; P:anaphase; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
148	A5D9H7	369	UBP12_BOVIN Ubiquitin carboxyl-terminal hydro...	73	1.3	35.8	33	52
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
149	Q52KZ6	370	UB12A_XENLA Ubiquitin carboxyl-terminal hydro...	73	1.4	35.8	33	52
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
150	D3ZU96	1325	UBP42_RAT Ubiquitin carboxyl-terminal hydrola...	61	0.018	42.4	33	49
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
151	B2RQC2	1324	UBP42_MOUSE Ubiquitin carboxyl-terminal hydro...	61	0.019	42.4	33	49
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.

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