Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR041W
Length:
669
Number of sequences:
5887
Description:
YBR041W FAT1 SGDID:S000000245, Chr II from 318266-320275, Genome Release 64-1-1, Verified ORF, "Very long chain fatty acyl-CoA synthetase and long chain fatty acid transporter; activates imported fatty acids with a preference for very long lengths (C20-C26); has a separate function in the transport of long chain fatty acids"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38225    669   FAT1_YEAST Very long-chain fatty acid transpo...6690     1397     100     100GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031235; C:intrinsic to internal side of plasma membrane; IDA:SGD.::GO:0005811; C:lipid particle; IDA:SGD.::GO:0005777; C:peroxisome; IMP:SGD.
GO:0005324; F:long-chain fatty acid transporter activity; IMP:SGD.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IMP:SGD.
GO:0000038; P:very long-chain fatty acid metabolic process; IMP:SGD.
2O42633    643   FAT1_COCHE Fatty acid transporter protein OS=...6144e-100     326     34     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003824; F:catalytic activity; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
3O14975    620   S27A2_HUMAN Very long-chain acyl-CoA syntheta...5745e-88     293     33     51GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005779; C:integral to peroxisomal membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050197; F:phytanate-CoA ligase activity; IDA:UniProtKB.::GO:0070251; F:pristanate-CoA ligase activity; IDA:UniProtKB.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:UniProtKB.
GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0001561; P:fatty acid alpha-oxidation; IDA:UniProtKB.::GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.::GO:0044539; P:long-chain fatty acid import; IDA:UniProtKB.::GO:0097089; P:methyl-branched fatty acid metabolic process; IDA:UniProtKB.
4O35488    620   S27A2_MOUSE Very long-chain acyl-CoA syntheta...5689e-83     280     33     52GO:0005788; C:endoplasmic reticulum lumen; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005779; C:integral to peroxisomal membrane; ISS:UniProtKB.::GO:0005792; C:microsome; IMP:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015245; F:fatty acid transporter activity; IDA:MGI.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:MGI.
GO:0042760; P:very long-chain fatty acid catabolic process; IMP:MGI.
5Q4R3Y4    643   S27A4_MACFA Long-chain fatty acid transport p...6103e-82     278     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
6Q5RDY4    643   S27A4_PONAB Long-chain fatty acid transport p...6103e-82     278     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
7Q60714    646   S27A1_MOUSE Long-chain fatty acid transport p...5467e-82     278     35     51GO:0031410; C:cytoplasmic vesicle; TAS:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015245; F:fatty acid transporter activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:MGI.
GO:0033211; P:adiponectin-mediated signaling pathway; IMP:MGI.::GO:0001676; P:long-chain fatty acid metabolic process; TAS:MGI.::GO:0015909; P:long-chain fatty acid transport; IMP:MGI.::GO:0031652; P:positive regulation of heat generation; IMP:MGI.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:MGI.::GO:0009409; P:response to cold; IMP:MGI.::GO:0032868; P:response to insulin stimulus; IMP:MGI.
8Q91VE0    643   S27A4_MOUSE Long-chain fatty acid transport p...5961e-81     277     34     48GO:0031526; C:brush border membrane; IDA:MGI.::GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005902; C:microvillus; IDA:MGI.
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:MGI.
GO:0015909; P:long-chain fatty acid transport; IMP:MGI.::GO:0001579; P:medium-chain fatty acid transport; IDA:MGI.::GO:0043588; P:skin development; IMP:MGI.::GO:0042760; P:very long-chain fatty acid catabolic process; IDA:MGI.
9Q6P1M0    643   S27A4_HUMAN Long-chain fatty acid transport p...6021e-81     277     33     48GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015245; F:fatty acid transporter activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0044539; P:long-chain fatty acid import; IDA:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome.
10P97849    646   S27A1_RAT Long-chain fatty acid transport pro...5872e-81     276     33     49GO:0005901; C:caveola; IDA:RGD.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.
GO:0015245; F:fatty acid transporter activity; NAS:RGD.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
11Q6PCB7    646   S27A1_HUMAN Long-chain fatty acid transport p...5966e-81     275     33     49GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0032049; P:cardiolipin biosynthetic process; IMP:UniProtKB.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0015909; P:long-chain fatty acid transport; TAS:Reactome.::GO:0071072; P:negative regulation of phospholipid biosynthetic process; IMP:UniProtKB.::GO:0006654; P:phosphatidic acid biosynthetic process; IMP:UniProtKB.::GO:0006656; P:phosphatidylcholine biosynthetic process; IMP:UniProtKB.::GO:0006646; P:phosphatidylethanolamine biosynthetic process; IMP:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IMP:UniProtKB.::GO:0006659; P:phosphatidylserine biosynthetic process; IMP:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome.
12Q3ZKN0    646   S27A1_BOVIN Long-chain fatty acid transport p...5714e-79     270     34     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
13Q9Y2P4    619   S27A6_HUMAN Long-chain fatty acid transport p...5773e-78     268     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0015909; P:long-chain fatty acid transport; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0000038; P:very long-chain fatty acid metabolic process; TAS:ProtInc.
14P97524    620   S27A2_RAT Very long-chain acyl-CoA synthetase...5713e-77     265     33     51GO:0005788; C:endoplasmic reticulum lumen; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005779; C:integral to peroxisomal membrane; ISS:UniProtKB.::GO:0005792; C:microsome; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; ISS:UniProtKB.
GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
15Q9Y2P5    690   S27A5_HUMAN Bile acyl-CoA synthetase OS=Homo ...5281e-72     254     33     51GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047747; F:cholate-CoA ligase activity; IEA:EC.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:UniProtKB.
GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0000038; P:very long-chain fatty acid metabolic process; IDA:UniProtKB.
16Q5K4L6    730   S27A3_HUMAN Long-chain fatty acid transport p...5552e-72     254     33     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
17Q4LDG0    689   S27A5_MOUSE Bile acyl-CoA synthetase OS=Mus m...5062e-70     247     35     53GO:0009925; C:basal plasma membrane; IDA:MGI.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047747; F:cholate-CoA ligase activity; IEA:EC.::GO:0015245; F:fatty acid transporter activity; IDA:MGI.::GO:0004467; F:long-chain fatty acid-CoA ligase activity; TAS:MGI.
GO:0008206; P:bile acid metabolic process; IMP:MGI.::GO:0046951; P:ketone body biosynthetic process; IMP:MGI.::GO:0001676; P:long-chain fatty acid metabolic process; TAS:MGI.::GO:0015911; P:plasma membrane long-chain fatty acid transport; IMP:MGI.::GO:0006642; P:triglyceride mobilization; IMP:MGI.
18O88561    667   S27A3_MOUSE Long-chain fatty acid transport p...5466e-70     246     33     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004321; F:fatty-acyl-CoA synthase activity; IMP:MGI.::GO:0004467; F:long-chain fatty acid-CoA ligase activity; TAS:MGI.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006637; P:acyl-CoA metabolic process; IC:MGI.::GO:0001676; P:long-chain fatty acid metabolic process; TAS:MGI.
19Q9ES38    690   S27A5_RAT Bile acyl-CoA synthetase OS=Rattus ...5271e-69     246     33     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047747; F:cholate-CoA ligase activity; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.
GO:0008206; P:bile acid metabolic process; IMP:RGD.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
20B2HHZ8    503   FAC17_MYCMM Long-chain-fatty-acid--CoA ligase...5123e-30     128     24     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:EC.
GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
21B7UI83    517   CAIC_ECO27 Probable crotonobetaine/carnitine-...4949e-27     118     26     41
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
22B4EY25    518   CAIC_PROMH Probable crotonobetaine/carnitine-...5602e-26     117     24     41
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
23Q8ZRX4    517   CAIC_SALTY Probable crotonobetaine/carnitine-...5493e-26     116     24     41
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
24B4TIH0    517   CAIC_SALHS Probable crotonobetaine/carnitine-...5493e-26     116     24     41
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
25B5F750    517   CAIC_SALA4 Probable crotonobetaine/carnitine-...5495e-26     116     25     41
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
26B5BL55    517   CAIC_SALPK Probable crotonobetaine/carnitine-...5548e-26     115     25     40
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
27Q5PIL0    517   CAIC_SALPA Probable crotonobetaine/carnitine-...5548e-26     115     25     40
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
28B5R1R0    517   CAIC_SALEP Probable crotonobetaine/carnitine-...5498e-26     115     25     41
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
29A9MYJ6    517   CAIC_SALPB Probable crotonobetaine/carnitine-...5492e-25     114     24     40
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
30B5FHG5    517   CAIC_SALDC Probable crotonobetaine/carnitine-...5493e-25     114     24     41
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
31Q8Z9L4    517   CAIC_SALTI Probable crotonobetaine/carnitine-...5493e-25     113     24     41
GO:0016878; F:acid-thiol ligase activity; IEA:InterPro.
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