Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR034C
Length:
348
Number of sequences:
5887
Description:
YBR034C HMT1 SGDID:S000000238, Chr II from 305976-304930, Genome Release 64-1-1, reverse complement, Verified ORF, "Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, affecting their activity and nuclear export; methylates U1 snRNP protein Snp1p and ribosomal protein Rps2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38074    348   HMT1_YEAST HNRNP arginine N-methyltransferase...3480     723     100     100GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IDA:SGD.::GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IMP:SGD.
GO:0006406; P:mRNA export from nucleus; IGI:SGD.::GO:0060567; P:negative regulation of transcription termination, DNA-dependent; IMP:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.
2Q9URX7    340   ANM1_SCHPO Probable protein arginine N-methyl...3291e-133     391     57     73GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0016274; F:protein-arginine N-methyltransferase activity; IMP:PomBase.
GO:0006406; P:mRNA export from nucleus; ISS:PomBase.::GO:0019919; P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; TAS:PomBase.
3Q54EF2    341   ANM1_DICDI Protein arginine N-methyltransfera...3363e-125     370     53     70GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0008469; F:histone-arginine N-methyltransferase activity; IEA:EC.
GO:0006406; P:mRNA export from nucleus; ISS:dictyBase.::GO:0045653; P:negative regulation of megakaryocyte differentiation; ISS:UniProtKB.
4Q9SU94    390   ANM11_ARATH Protein arginine N-methyltransfer...3172e-118     355     53     72GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0008469; F:histone-arginine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q0J2C6    387   ANM1_ORYSJ Probable protein arginine N-methyl...3092e-114     344     51     72GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
6A2Z0C0    387   ANM1_ORYSI Probable protein arginine N-methyl...3092e-114     344     51     72GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
7O82210    366   ANM12_ARATH Probable protein arginine N-methy...3095e-114     342     53     72GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q28F07    351   ANM1_XENTR Protein arginine N-methyltransfera...3264e-111     334     50     70GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0044020; F:histone methyltransferase activity (H4-R3 specific); ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
GO:0007552; P:metamorphosis; ISS:UniProtKB.::GO:0045653; P:negative regulation of megakaryocyte differentiation; ISS:UniProtKB.::GO:0022008; P:neurogenesis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0031056; P:regulation of histone modification; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q99873    361   ANM1_HUMAN Protein arginine N-methyltransfera...3122e-110     333     51     70GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0044020; F:histone methyltransferase activity (H4-R3 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0045653; P:negative regulation of megakaryocyte differentiation; IDA:UniProtKB.::GO:0031175; P:neuron projection development; IMP:UniProtKB.
10Q63009    353   ANM1_RAT Protein arginine N-methyltransferase...3124e-110     332     51     70GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0016275; F:[cytochrome c-arginine N-methyltransferase activity; IDA:MGI.::GO:0044020; F:histone methyltransferase activity (H4-R3 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IDA:MGI.::GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IDA:MGI.::GO:0030519; F:snoRNP binding; IDA:RGD.
GO:0045653; P:negative regulation of megakaryocyte differentiation; ISS:UniProtKB.]
11Q9JIF0    371   ANM1_MOUSE Protein arginine N-methyltransfera...3128e-110     332     51     70GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0044020; F:histone methyltransferase activity (H4-R3 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0045653; P:negative regulation of megakaryocyte differentiation; ISS:UniProtKB.
12Q6VRB0    351   ANM1B_XENLA Protein arginine N-methyltransfer...3248e-110     331     50     70GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0044020; F:histone methyltransferase activity (H4-R3 specific); ISS:UniProtKB.
GO:0045653; P:negative regulation of megakaryocyte differentiation; ISS:UniProtKB.::GO:0022008; P:neurogenesis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q8AV13    369   ANM1A_XENLA Protein arginine N-methyltransfer...3242e-109     331     50     69GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IPI:UniProtKB.
GO:0044020; F:histone methyltransferase activity (H4-R3 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007552; P:metamorphosis; IMP:UniProtKB.::GO:0045653; P:negative regulation of megakaryocyte differentiation; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0031056; P:regulation of histone modification; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q5RGQ2    419   ANM8B_DANRE Protein arginine N-methyltransfer...3163e-108     329     50     68GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; ISS:UniProtKB.::GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; ISS:UniProtKB.
15Q6PAK3    394   ANM8_MOUSE Protein arginine N-methyltransfera...3121e-107     327     50     70GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:HGNC.::GO:0046982; F:protein heterodimerization activity; ISS:HGNC.::GO:0042803; F:protein homodimerization activity; ISS:HGNC.::GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; ISS:UniProtKB.::GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; ISS:HGNC.
16Q9NR22    394   ANM8_HUMAN Protein arginine N-methyltransfera...3122e-107     327     50     70GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0008469; F:histone-arginine N-methyltransferase activity; IDA:HGNC.::GO:0046982; F:protein heterodimerization activity; IDA:HGNC.::GO:0042803; F:protein homodimerization activity; IDA:HGNC.::GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IDA:UniProtKB.::GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IDA:UniProtKB.
GO:0043393; P:regulation of protein binding; TAS:HGNC.
17O60678    531   ANM3_HUMAN Protein arginine N-methyltransfera...3026e-96     301     48     66
GO:0008270; F:zinc ion binding; IEA:InterPro.
18O70467    528   ANM3_RAT Protein arginine N-methyltransferase...3173e-94     297     47     63
GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
19Q922H1    532   ANM3_MOUSE Protein arginine N-methyltransfera...3211e-91     290     46     63GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
20Q08A71    435   ANM6_ARATH Probable protein arginine N-methyl...3401e-78     254     39     57GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
21Q75G68    395   ANM62_ORYSJ Probable protein arginine N-methy...3352e-77     249     40     56
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
22A2Z8S0    395   ANM62_ORYSI Probable protein arginine N-methy...3352e-77     249     40     56
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
23Q7XKC0    391   ANM61_ORYSJ Probable protein arginine N-methy...3363e-76     246     39     59
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
24A2XYY8    379   ANM61_ORYSI Probable protein arginine N-methy...3362e-75     244     39     59
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
25O13648    543   ANM3_SCHPO Ribosomal protein arginine N-methy...3257e-75     246     40     56GO:0005829; C:cytosol; IDA:PomBase.::GO:0005840; C:ribosome; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0016274; F:protein-arginine N-methyltransferase activity; IMP:PomBase.::GO:0043022; F:ribosome binding; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019919; P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; IPI:PomBase.::GO:0042254; P:ribosome biogenesis; IMP:PomBase.
26Q6NWG4    349   ANM6_DANRE Protein arginine N-methyltransfera...3274e-69     226     39     58GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0070612; F:histone methyltransferase activity (H2A-R3 specific); ISS:UniProtKB.::GO:0070611; F:histone methyltransferase activity (H3-R2 specific); ISS:UniProtKB.::GO:0044020; F:histone methyltransferase activity (H4-R3 specific); ISS:UniProtKB.::GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; ISS:UniProtKB.::GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q6NZB1    378   ANM6_MOUSE Protein arginine N-methyltransfera...3262e-66     220     37     54GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0070612; F:histone methyltransferase activity (H2A-R3 specific); ISS:UniProtKB.::GO:0070611; F:histone methyltransferase activity (H3-R2 specific); ISS:UniProtKB.::GO:0044020; F:histone methyltransferase activity (H4-R3 specific); ISS:UniProtKB.::GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; ISS:UniProtKB.::GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q96LA8    375   ANM6_HUMAN Protein arginine N-methyltransfera...3343e-66     219     35     54GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0070612; F:histone methyltransferase activity (H2A-R3 specific); IDA:UniProtKB.::GO:0070611; F:histone methyltransferase activity (H3-R2 specific); IDA:UniProtKB.::GO:0044020; F:histone methyltransferase activity (H4-R3 specific); IDA:UniProtKB.::GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IDA:UniProtKB.::GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IDA:UniProtKB.
GO:0006284; P:base-excision repair; TAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q68EZ3    340   ANM6_XENLA Protein arginine N-methyltransfera...3407e-65     215     35     54GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0070612; F:histone methyltransferase activity (H2A-R3 specific); ISS:UniProtKB.::GO:0070611; F:histone methyltransferase activity (H3-R2 specific); ISS:UniProtKB.::GO:0044020; F:histone methyltransferase activity (H4-R3 specific); ISS:UniProtKB.::GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; ISS:UniProtKB.::GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30P55345    433   ANM2_HUMAN Protein arginine N-methyltransfera...3203e-64     216     36     57GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:UniProtKB.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0042975; F:peroxisome proliferator activated receptor binding; IPI:UniProtKB.::GO:0033142; F:progesterone receptor binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0042974; F:retinoic acid receptor binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
GO:0048588; P:developmental cell growth; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB.
31A3BMN9    620   ANM3_ORYSJ Probable protein arginine N-methyl...3068e-64     219     41     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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