Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR028C
Length:
525
Number of sequences:
5887
Description:
YBR028C YPK3 SGDID:S000000232, Chr II from 296002-294425, Genome Release 64-1-1, reverse complement, Verified ORF, "An AGC kinase phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
961O96013    591   PAK4_HUMAN Serine/threonine-protein kinase PA...2151e-20     99     28     53GO:0005794; C:Golgi apparatus; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016049; P:cell growth; TAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB.
962Q9HGY5    326   PHO85_CANAX Negative regulator of the PHO sys...2511e-20     96.3     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
963O49717    554   CDPKF_ARATH Calcium-dependent protein kinase ...3071e-20     98.6     28     44GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
964P20689    610   MYLK2_RAT Myosin light chain kinase 2, skelet...3242e-20     99     26     45GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0008021; C:synaptic vesicle; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0032027; F:myosin light chain binding; IMP:RGD.::GO:0004687; F:myosin light chain kinase activity; IDA:RGD.
GO:0018105; P:peptidyl-serine phosphorylation; TAS:RGD.::GO:0051272; P:positive regulation of cellular component movement; IMP:RGD.::GO:0031448; P:positive regulation of fast-twitch skeletal muscle fiber contraction; IMP:RGD.::GO:0051726; P:regulation of cell cycle; IMP:RGD.::GO:0043408; P:regulation of MAPK cascade; IMP:RGD.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:RGD.::GO:0048489; P:synaptic vesicle transport; IMP:RGD.::GO:0006833; P:water transport; IMP:RGD.
965Q99KH8    431   STK24_MOUSE Serine/threonine-protein kinase 2...2052e-20     97.8     29     54GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008631; P:induction of apoptosis by oxidative stress; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
966Q10056    589   SHK2_SCHPO Serine/threonine-protein kinase sh...2752e-20     98.6     27     45GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0032488; P:Cdc42 protein signal transduction; NAS:PomBase.::GO:0000165; P:MAPK cascade; NAS:PomBase.
967P17157    305   PHO85_YEAST Cyclin-dependent protein kinase P...1722e-20     95.9     33     55GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0050849; P:negative regulation of calcium-mediated signaling; IGI:SGD.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0016242; P:negative regulation of macroautophagy; IMP:SGD.::GO:0045936; P:negative regulation of phosphate metabolic process; IGI:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0016239; P:positive regulation of macroautophagy; IMP:SGD.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IGI:SGD.::GO:0032880; P:regulation of protein localization; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.
968Q12469    655   SKM1_YEAST Serine/threonine-protein kinase SK...2192e-20     98.6     30     52GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000920; P:cytokinetic cell separation; IMP:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0035376; P:sterol import; IMP:SGD.
969Q8FUI4    520   PKN2_COREF Serine/threonine-protein kinases d...1812e-20     98.2     31     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
970Q8BHI9    436   NIM1_MOUSE Serine/threonine-protein kinase NI...2212e-20     97.4     28     48
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
971Q8VCR8    613   MYLK2_MOUSE Myosin light chain kinase 2, skel...2662e-20     98.6     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0055007; P:cardiac muscle cell differentiation; IEP:UniProtKB.::GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.::GO:0014816; P:satellite cell differentiation; IMP:UniProtKB.::GO:0035914; P:skeletal muscle cell differentiation; IEP:UniProtKB.
972P49137    400   MAPK2_HUMAN MAP kinase-activated protein kina...2972e-20     97.1     28     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.::GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0006954; P:inflammatory response; ISS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0019370; P:leukotriene biosynthetic process; TAS:Reactome.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0006692; P:prostanoid metabolic process; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0032675; P:regulation of interleukin-6 production; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; IDA:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
973P43450    298   CDK2_CARAU Cyclin-dependent kinase 2 OS=Caras...2512e-20     95.5     31     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
974Q6PDN3    1941   MYLK_MOUSE Myosin light chain kinase, smooth ...2822e-20     99.4     27     47GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0014820; P:tonic smooth muscle contraction; IMP:UniProtKB.
975P38973    301   CC2H1_TRYBB Cell division control protein 2 h...2362e-20     95.5     30     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
976P34556    332   CDK1_CAEEL Cyclin-dependent kinase 1 OS=Caeno...2472e-20     95.9     28     48GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:WormBase.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IMP:UniProtKB.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0001556; P:oocyte maturation; IMP:WormBase.::GO:0045836; P:positive regulation of meiosis; IMP:WormBase.::GO:0051446; P:positive regulation of meiotic cell cycle; IMP:UniProtKB.::GO:0035046; P:pronuclear migration; IMP:WormBase.
977Q6FKD4    302   PHO85_CANGA Negative regulator of the PHO sys...1842e-20     95.5     32     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
978P49071    359   MAPK2_DROME MAP kinase-activated protein kina...2902e-20     96.3     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.
979Q16816    387   PHKG1_HUMAN Phosphorylase b kinase gamma cata...2972e-20     96.7     27     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0006006; P:glucose metabolic process; TAS:Reactome.::GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.::GO:0005980; P:glycogen catabolic process; TAS:Reactome.
980Q8BTW9    593   PAK4_MOUSE Serine/threonine-protein kinase PA...2792e-20     98.2     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
981Q23023    856   UNC51_CAEEL Serine/threonine-protein kinase u...1692e-20     98.6     31     53GO:0030424; C:axon; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0043277; P:apoptotic cell clearance; IMP:WormBase.::GO:0006914; P:autophagy; IGI:WormBase.::GO:0048675; P:axon extension; IMP:WormBase.::GO:0007411; P:axon guidance; IMP:WormBase.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0040024; P:dauer larval development; IGI:WormBase.::GO:0008340; P:determination of adult lifespan; IGI:WormBase.::GO:0070265; P:necrotic cell death; IMP:WormBase.::GO:0012501; P:programmed cell death; IGI:WormBase.::GO:0046777; P:protein autophosphorylation; IDA:WormBase.::GO:0030516; P:regulation of axon extension; IMP:WormBase.::GO:0040014; P:regulation of multicellular organism growth; IGI:WormBase.::GO:0032880; P:regulation of protein localization; IMP:WormBase.::GO:0035121; P:tail morphogenesis; IMP:WormBase.
982Q00534    326   CDK6_HUMAN Cyclin-dependent kinase 6 OS=Homo ...2622e-20     95.9     30     47GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0001726; C:ruffle; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0030332; F:cyclin binding; IPI:BHF-UCL.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:BHF-UCL.
GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0007050; P:cell cycle arrest; TAS:UniProtKB.::GO:0043697; P:cell dedifferentiation; IMP:BHF-UCL.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021542; P:dentate gyrus development; ISS:UniProtKB.::GO:0000080; P:G1 phase of mitotic cell cycle; IEP:BHF-UCL.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.::GO:0048699; P:generation of neurons; ISS:UniProtKB.::GO:0021670; P:lateral ventricle development; ISS:UniProtKB.::GO:2000773; P:negative regulation of cellular senescence; IDA:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IDA:BHF-UCL.::GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; IMP:BHF-UCL.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0003323; P:type B pancreatic cell development; IDA:UniProtKB.
983P31325    406   PHKG2_RAT Phosphorylase b kinase gamma cataly...2682e-20     96.7     28     44GO:0005964; C:phosphorylase kinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0019899; F:enzyme binding; IDA:RGD.::GO:0004689; F:phosphorylase kinase activity; IDA:RGD.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
984O74304    1436   WIN1_SCHPO MAP kinase kinase kinase win1 OS=S...2492e-20     99     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IGI:PomBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0031098; P:stress-activated protein kinase signaling cascade; IGI:PomBase.
985Q8VBY2    505   KKCC1_MOUSE Calcium/calmodulin-dependent prot...3792e-20     97.8     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
986P23437    297   CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenop...2442e-20     95.1     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
987Q6C3D7    1125   STE20_YARLI Serine/threonine-protein kinase S...2342e-20     99     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
988Q5Z6X0    514   CIPKP_ORYSJ CBL-interacting protein kinase 25...3032e-20     97.8     24     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
989Q9DB30    406   PHKG2_MOUSE Phosphorylase b kinase gamma cata...2222e-20     96.7     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
990P49139    366   MAPK2_RABIT MAP kinase-activated protein kina...2932e-20     96.3     27     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006954; P:inflammatory response; ISS:UniProtKB.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0032675; P:regulation of interleukin-6 production; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; ISS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.
991Q55CE0    677   MKCF_DICDI Probable serine/threonine-protein ...2492e-20     98.2     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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