Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR017C
Length:
918
Number of sequences:
5887
Description:
YBR017C KAP104 SGDID:S000000221, Chr II from 273703-270947, Genome Release 64-1-1, reverse complement, Verified ORF, "Transportin or cytosolic karyopherin beta 2; functions in the rg-nuclear localization signal-mediated nuclear import/reimport of mRNA-binding proteins Nab2p and Hrp1p; regulates asymmetric protein synthesis in daughter cells during mitosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38217    918   IMB2_YEAST Importin subunit beta-2 OS=Sacchar...9180     1890     100     100GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.
GO:0008139; F:nuclear localization sequence binding; IPI:SGD.
GO:0007049; P:cell cycle; IMP:SGD.::GO:0006609; P:mRNA-binding (hnRNP) protein import into nucleus; IDA:SGD.::GO:0042991; P:transcription factor import into nucleus; IMP:SGD.
2O14089    910   IMB2_SCHPO Importin subunit beta-2 OS=Schizos...8811e-138     443     33     56GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.::GO:0005643; C:nuclear pore; NAS:PomBase.
GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase.
3Q8BFY9    898   TNPO1_MOUSE Transportin-1 OS=Mus musculus (Mo...8722e-131     424     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
4Q92973    898   TNPO1_HUMAN Transportin-1 OS=Homo sapiens (Hu...8722e-131     424     35     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.
5Q3SYU7    898   TNPO1_BOVIN Transportin-1 OS=Bos taurus (Bovi...8723e-131     423     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
6Q99LG2    887   TNPO2_MOUSE Transportin-2 OS=Mus musculus (Mo...8712e-122     399     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
7O14787    897   TNPO2_HUMAN Transportin-2 OS=Homo sapiens (Hu...8791e-119     392     33     54GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
8Q55CQ7    931   TNPO_DICDI Transportin OS=Dictyostelium disco...3625e-21     102     27     48GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005635; C:nuclear envelope; ISS:dictyBase.
GO:0008139; F:nuclear localization sequence binding; ISS:dictyBase.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; ISS:dictyBase.
9O74476    1095   IMB3_SCHPO Importin subunit beta-3 OS=Schizos...2810.000001     56.2     25     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.
GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase.
GO:0006606; P:protein import into nucleus; IDA:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.
10Q06142    861   IMB1_YEAST Importin subunit beta-1 OS=Sacchar...1460.000003     55.1     24     47GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IDA:SGD.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0051292; P:nuclear pore complex assembly; IMP:SGD.::GO:0006656; P:phosphatidylcholine biosynthetic process; IMP:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.::GO:0060188; P:regulation of protein desumoylation; IMP:SGD.
11P70168    876   IMB1_MOUSE Importin subunit beta-1 OS=Mus mus...1210.000007     53.9     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:MGI.
GO:0008565; F:protein transporter activity; IDA:MGI.
GO:0006610; P:ribosomal protein import into nucleus; IDA:MGI.
12P52296    875   IMB1_RAT Importin subunit beta-1 OS=Rattus no...1210.000007     53.5     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
13Q14974    876   IMB1_HUMAN Importin subunit beta-1 OS=Homo sa...1190.0001     49.7     24     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:Reactome.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.::GO:0046796; P:viral genome transport in host cell; TAS:Reactome.::GO:0019058; P:viral infectious cycle; TAS:Reactome.
14Q8BIV3    1105   RNBP6_MOUSE Ran-binding protein 6 OS=Mus musc...2790.0005     47.8     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
15Q54WR2    2667   GCN1L_DICDI Translational activator gcn1 OS=D...1120.001     47     28     42
GO:0005488; F:binding; IEA:InterPro.
GO:0006448; P:regulation of translational elongation; ISS:dictyBase.
16O18388    884   IMB_DROME Importin subunit beta OS=Drosophila...2190.001     46.6     21     42GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005643; C:nuclear pore; ISS:FlyBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0008320; F:protein transmembrane transporter activity; ISS:FlyBase.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007304; P:chorion-containing eggshell formation; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0006607; P:NLS-bearing substrate import into nucleus; IDA:FlyBase.::GO:0051533; P:positive regulation of NFAT protein import into nucleus; IMP:FlyBase.::GO:0000059; P:protein import into nucleus, docking; IDA:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.
17O60518    1105   RNBP6_HUMAN Ran-binding protein 6 OS=Homo sap...2770.005     44.3     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
18Q92616    2671   GCN1L_HUMAN Translational activator GCN1 OS=H...1320.005     44.7     27     42GO:0005840; C:ribosome; NAS:UniProtKB.
GO:0008135; F:translation factor activity, nucleic acid binding; NAS:UniProtKB.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
19O00410    1097   IPO5_HUMAN Importin-5 OS=Homo sapiens (Human)...1740.069     40.8     25     44GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0008565; F:protein transporter activity; IEA:InterPro.::GO:0008536; F:Ran GTPase binding; TAS:ProtInc.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.
20Q8BKC5    1097   IPO5_MOUSE Importin-5 OS=Mus musculus (Mouse)...1740.069     40.8     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro.
21O60100    1067   IMB4_SCHPO Probable importin subunit beta-4 O...1570.071     40.8     24     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; TAS:PomBase.
GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase.
22P33892    2672   GCN1_YEAST Translational activator GCN1 OS=Sa...1300.079     40.8     27     42GO:0022626; C:cytosolic ribosome; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006448; P:regulation of translational elongation; IMP:SGD.
23Q96321    532   IMA1_ARATH Importin subunit alpha-1 OS=Arabid...1830.26     38.5     24     44GO:0005618; C:cell wall; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005635; C:nuclear envelope; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
24Q8VI75    1082   IPO4_MOUSE Importin-4 OS=Mus musculus (Mouse)...2430.41     38.1     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
25Q10105    2670   GCN1_SCHPO Translational activator gcn1 OS=Sc...710.42     38.1     32     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005488; F:binding; IEA:InterPro.
GO:0006448; P:regulation of translational elongation; ISS:PomBase.
26P34036    4730   DYHC_DICDI Dynein heavy chain, cytoplasmic OS...1520.46     38.1     24     45GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005813; C:centrosome; IDA:dictyBase.::GO:0005868; C:cytoplasmic dynein complex; IDA:dictyBase.::GO:0030139; C:endocytic vesicle; IDA:dictyBase.::GO:0005874; C:microtubule; IPI:dictyBase.
GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0042623; F:ATPase activity, coupled; IDA:dictyBase.::GO:0003777; F:microtubule motor activity; IEA:InterPro.::GO:0015631; F:tubulin binding; IDA:dictyBase.
GO:0031122; P:cytoplasmic microtubule organization; IMP:dictyBase.::GO:0007018; P:microtubule-based movement; IEA:InterPro.
27O57589    242   SURF2_TAKRU Surfeit locus protein 2 OS=Takifu...870.92     36.2     30     45
28P37686    383   ADH2_ECOLI Probable alcohol dehydrogenase OS=...681.8     35.8     29     53
GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
29Q8TEX9    1081   IPO4_HUMAN Importin-4 OS=Homo sapiens (Human)...2312     35.8     22     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
30Q8QGX4    4134   PRKDC_CHICK DNA-dependent protein kinase cata...204.4     35     60     85GO:0070419; C:nonhomologous end joining complex; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004677; F:DNA-dependent protein kinase activity; IEA:InterPro.
GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0006303; P:double-strand break repair via nonhomologous end joining; TAS:Reactome.
31O51057    308   FOLD_BORBU Bifunctional protein FolD OS=4680)...1255.3     33.9     27     42
GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
records
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