rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P38217 | 918 | IMB2_YEAST Importin subunit beta-2 OS=Sacchar... | 918 | 0 | 1890 | 100 | 100 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IPI:SGD. | | | | | | | | | | GO:0007049; P:cell cycle; IMP:SGD.::GO:0006609; P:mRNA-binding (hnRNP) protein import into nucleus; IDA:SGD.::GO:0042991; P:transcription factor import into nucleus; IMP:SGD. | 2 | O14089 | 910 | IMB2_SCHPO Importin subunit beta-2 OS=Schizos... | 881 | 1e-138 | 443 | 33 | 56 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.::GO:0005643; C:nuclear pore; NAS:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase. | 3 | Q8BFY9 | 898 | TNPO1_MOUSE Transportin-1 OS=Mus musculus (Mo... | 872 | 2e-131 | 424 | 35 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 4 | Q92973 | 898 | TNPO1_HUMAN Transportin-1 OS=Homo sapiens (Hu... | 872 | 2e-131 | 424 | 35 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc. | 5 | Q3SYU7 | 898 | TNPO1_BOVIN Transportin-1 OS=Bos taurus (Bovi... | 872 | 3e-131 | 423 | 34 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 6 | Q99LG2 | 887 | TNPO2_MOUSE Transportin-2 OS=Mus musculus (Mo... | 871 | 2e-122 | 399 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 7 | O14787 | 897 | TNPO2_HUMAN Transportin-2 OS=Homo sapiens (Hu... | 879 | 1e-119 | 392 | 33 | 54 | GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 8 | Q55CQ7 | 931 | TNPO_DICDI Transportin OS=Dictyostelium disco... | 362 | 5e-21 | 102 | 27 | 48 | GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005635; C:nuclear envelope; ISS:dictyBase. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; ISS:dictyBase.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006606; P:protein import into nucleus; ISS:dictyBase. | 9 | O74476 | 1095 | IMB3_SCHPO Importin subunit beta-3 OS=Schizos... | 281 | 0.000001 | 56.2 | 25 | 44 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0006606; P:protein import into nucleus; IDA:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase. | 10 | Q06142 | 861 | IMB1_YEAST Importin subunit beta-1 OS=Sacchar... | 146 | 0.000003 | 55.1 | 24 | 47 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IDA:SGD.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:SGD. | | | | | | | | | | GO:0051292; P:nuclear pore complex assembly; IMP:SGD.::GO:0006656; P:phosphatidylcholine biosynthetic process; IMP:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.::GO:0060188; P:regulation of protein desumoylation; IMP:SGD. | 11 | P70168 | 876 | IMB1_MOUSE Importin subunit beta-1 OS=Mus mus... | 121 | 0.000007 | 53.9 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:MGI. | | | | | | | | | | GO:0008565; F:protein transporter activity; IDA:MGI. | | | | | | | | | | GO:0006610; P:ribosomal protein import into nucleus; IDA:MGI. | 12 | P52296 | 875 | IMB1_RAT Importin subunit beta-1 OS=Rattus no... | 121 | 0.000007 | 53.5 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 13 | Q14974 | 876 | IMB1_HUMAN Importin subunit beta-1 OS=Homo sa... | 119 | 0.0001 | 49.7 | 24 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:Reactome.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.::GO:0046796; P:viral genome transport in host cell; TAS:Reactome.::GO:0019058; P:viral infectious cycle; TAS:Reactome. | 14 | Q8BIV3 | 1105 | RNBP6_MOUSE Ran-binding protein 6 OS=Mus musc... | 279 | 0.0005 | 47.8 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 15 | Q54WR2 | 2667 | GCN1L_DICDI Translational activator gcn1 OS=D... | 112 | 0.001 | 47 | 28 | 42 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006448; P:regulation of translational elongation; ISS:dictyBase. | 16 | O18388 | 884 | IMB_DROME Importin subunit beta OS=Drosophila... | 219 | 0.001 | 46.6 | 21 | 42 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005643; C:nuclear pore; ISS:FlyBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008320; F:protein transmembrane transporter activity; ISS:FlyBase. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007304; P:chorion-containing eggshell formation; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0006607; P:NLS-bearing substrate import into nucleus; IDA:FlyBase.::GO:0051533; P:positive regulation of NFAT protein import into nucleus; IMP:FlyBase.::GO:0000059; P:protein import into nucleus, docking; IDA:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase. | 17 | O60518 | 1105 | RNBP6_HUMAN Ran-binding protein 6 OS=Homo sap... | 277 | 0.005 | 44.3 | 26 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 18 | Q92616 | 2671 | GCN1L_HUMAN Translational activator GCN1 OS=H... | 132 | 0.005 | 44.7 | 27 | 42 | GO:0005840; C:ribosome; NAS:UniProtKB. | | | | | | | | | | GO:0008135; F:translation factor activity, nucleic acid binding; NAS:UniProtKB. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 19 | O00410 | 1097 | IPO5_HUMAN Importin-5 OS=Homo sapiens (Human)... | 174 | 0.069 | 40.8 | 25 | 44 | GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0008565; F:protein transporter activity; IEA:InterPro.::GO:0008536; F:Ran GTPase binding; TAS:ProtInc. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB. | 20 | Q8BKC5 | 1097 | IPO5_MOUSE Importin-5 OS=Mus musculus (Mouse)... | 174 | 0.069 | 40.8 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | | 21 | O60100 | 1067 | IMB4_SCHPO Probable importin subunit beta-4 O... | 157 | 0.071 | 40.8 | 24 | 45 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase. | 22 | P33892 | 2672 | GCN1_YEAST Translational activator GCN1 OS=Sa... | 130 | 0.079 | 40.8 | 27 | 42 | GO:0022626; C:cytosolic ribosome; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006448; P:regulation of translational elongation; IMP:SGD. | 23 | Q96321 | 532 | IMA1_ARATH Importin subunit alpha-1 OS=Arabid... | 183 | 0.26 | 38.5 | 24 | 44 | GO:0005618; C:cell wall; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005635; C:nuclear envelope; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006606; P:protein import into nucleus; IEA:InterPro. | 24 | Q8VI75 | 1082 | IPO4_MOUSE Importin-4 OS=Mus musculus (Mouse)... | 243 | 0.41 | 38.1 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 25 | Q10105 | 2670 | GCN1_SCHPO Translational activator gcn1 OS=Sc... | 71 | 0.42 | 38.1 | 32 | 48 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006448; P:regulation of translational elongation; ISS:PomBase. | 26 | P34036 | 4730 | DYHC_DICDI Dynein heavy chain, cytoplasmic OS... | 152 | 0.46 | 38.1 | 24 | 45 | GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005813; C:centrosome; IDA:dictyBase.::GO:0005868; C:cytoplasmic dynein complex; IDA:dictyBase.::GO:0030139; C:endocytic vesicle; IDA:dictyBase.::GO:0005874; C:microtubule; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0042623; F:ATPase activity, coupled; IDA:dictyBase.::GO:0003777; F:microtubule motor activity; IEA:InterPro.::GO:0015631; F:tubulin binding; IDA:dictyBase. | | | | | | | | | | GO:0031122; P:cytoplasmic microtubule organization; IMP:dictyBase.::GO:0007018; P:microtubule-based movement; IEA:InterPro. | 27 | O57589 | 242 | SURF2_TAKRU Surfeit locus protein 2 OS=Takifu... | 87 | 0.92 | 36.2 | 30 | 45 | | | | | | | | | | | | | | | | | | | | | | 28 | P37686 | 383 | ADH2_ECOLI Probable alcohol dehydrogenase OS=... | 68 | 1.8 | 35.8 | 29 | 53 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | | 29 | Q8TEX9 | 1081 | IPO4_HUMAN Importin-4 OS=Homo sapiens (Human)... | 231 | 2 | 35.8 | 22 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 30 | Q8QGX4 | 4134 | PRKDC_CHICK DNA-dependent protein kinase cata... | 20 | 4.4 | 35 | 60 | 85 | GO:0070419; C:nonhomologous end joining complex; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004677; F:DNA-dependent protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0006303; P:double-strand break repair via nonhomologous end joining; TAS:Reactome. | 31 | O51057 | 308 | FOLD_BORBU Bifunctional protein FolD OS=4680)... | 125 | 5.3 | 33.9 | 27 | 42 | | | | | | | | | | | GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW. |