Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBR006W
Length:
497
Number of sequences:
5887
Description:
YBR006W UGA2 SGDID:S000000210, Chr II from 247010-248503, Genome Release 64-1-1, Verified ORF, "Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38067    497   UGA2_YEAST Succinate-semialdehyde dehydrogena...4970     1026     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+ activity; IMP:SGD.
GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0009450; P:gamma-aminobutyric acid catabolic process; IMP:SGD.::GO:0006540; P:glutamate decarboxylation to succinate; IMP:SGD.]
2Q9US47    547   SSDH1_SCHPO Putative succinate-semialdehyde d...4860     540     55     72GO:0005829; C:cytosol; IDA:PomBase.
GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+ activity; IEA:EC.::GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:PomBase.
GO:0006538; P:glutamate catabolic process; ISS:PomBase.]
3P25526    482   GABD_ECOLI Succinate-semialdehyde dehydrogena...4821e-179     520     53     69GO:0005737; C:cytoplasm; IDA:EcoliWiki.
GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+ activity; IDA:UniProtKB.::GO:0004777; F:succinate-semialdehyde dehydrogenase activity; IDA:UniProtKB.
GO:0009450; P:gamma-aminobutyric acid catabolic process; IDA:UniProtKB.]
4Q8BWF0    523   SSDH_MOUSE Succinate-semialdehyde dehydrogena...4814e-154     456     49     64GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
GO:0006083; P:acetate metabolic process; IMP:MGI.::GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0006681; P:galactosylceramide metabolic process; IMP:MGI.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0006678; P:glucosylceramide metabolic process; IMP:MGI.::GO:0006536; P:glutamate metabolic process; IMP:MGI.::GO:0006541; P:glutamine metabolic process; IMP:MGI.::GO:0006749; P:glutathione metabolic process; IMP:MGI.::GO:0006650; P:glycerophospholipid metabolic process; IMP:MGI.::GO:0042135; P:neurotransmitter catabolic process; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0022904; P:respiratory electron transport chain; IMP:MGI.::GO:0046459; P:short-chain fatty acid metabolic process; IMP:MGI.::GO:0006105; P:succinate metabolic process; IMP:MGI.
5P51650    523   SSDH_RAT Succinate-semialdehyde dehydrogenase...4815e-154     456     48     65GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0031406; F:carboxylic acid binding; IPI:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0004777; F:succinate-semialdehyde dehydrogenase activity; IDA:UniProtKB.
GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0006105; P:succinate metabolic process; IDA:RGD.
6Q9SAK4    528   SSDH_ARATH Succinate-semialdehyde dehydrogena...4841e-153     455     49     66GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005759; C:mitochondrial matrix; IDA:TAIR.
GO:0005507; F:copper ion binding; IDA:TAIR.::GO:0051287; F:NAD binding; IDA:TAIR.::GO:0004777; F:succinate-semialdehyde dehydrogenase activity; IDA:TAIR.
GO:0009450; P:gamma-aminobutyric acid catabolic process; IDA:TAIR.::GO:0006540; P:glutamate decarboxylation to succinate; IDA:TAIR.::GO:0072593; P:reactive oxygen species metabolic process; IMP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0009416; P:response to light stimulus; IMP:TAIR.
7P55653    491   GABD_RHISN Probable succinate-semialdehyde de...4935e-153     452     47     65
GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
8Q9UTM8    493   SSDH2_SCHPO Putative succinate-semialdehyde d...4922e-148     441     45     63GO:0005829; C:cytosol; IDA:PomBase.
GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+ activity; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006538; P:glutamate catabolic process; ISS:PomBase.]
9B9F3B6    527   SSDH_ORYSJ Succinate-semialdehyde dehydrogena...4792e-148     442     48     67GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004777; F:succinate-semialdehyde dehydrogenase activity; IEA:EC.
10P51649    535   SSDH_HUMAN Succinate-semialdehyde dehydrogena...4803e-148     441     48     64GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005625; C:soluble fraction; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IC:UniProtKB.::GO:0004777; F:succinate-semialdehyde dehydrogenase activity; IDA:UniProtKB.
GO:0006083; P:acetate metabolic process; ISS:UniProtKB.::GO:0007417; P:central nervous system development; IMP:UniProtKB.::GO:0006681; P:galactosylceramide metabolic process; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; IDA:UniProtKB.::GO:0006006; P:glucose metabolic process; ISS:UniProtKB.::GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.::GO:0006541; P:glutamine metabolic process; ISS:UniProtKB.::GO:0006749; P:glutathione metabolic process; ISS:UniProtKB.::GO:0006650; P:glycerophospholipid metabolic process; ISS:UniProtKB.::GO:0042135; P:neurotransmitter catabolic process; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; TAS:Reactome.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0022904; P:respiratory electron transport chain; ISS:UniProtKB.::GO:0046459; P:short-chain fatty acid metabolic process; ISS:UniProtKB.::GO:0006105; P:succinate metabolic process; ISS:UniProtKB.
11Q6A2H1    535   SSDH_GORGO Succinate-semialdehyde dehydrogena...4801e-147     440     48     64GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
12Q3MSM3    535   SSDH_HYLLA Succinate-semialdehyde dehydrogena...4801e-147     440     48     65GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
13Q3MSM4    535   SSDH_PANPA Succinate-semialdehyde dehydrogena...4802e-147     440     48     64GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
14P94428    462   GABD_BACSU Succinate-semialdehyde dehydrogena...4572e-147     437     49     65
GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
15Q6A2H0    535   SSDH_PANTR Succinate-semialdehyde dehydrogena...4804e-147     439     48     64GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
16Q6A2H2    535   SSDH_PONPY Succinate-semialdehyde dehydrogena...4801e-145     435     48     64GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
GO:0004777; F:succinate-semialdehyde dehydrogenase activity; ISS:UniProtKB.
GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0009450; P:gamma-aminobutyric acid catabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
17Q9URW9    496   YLX7_SCHPO Putative aldehyde dehydrogenase-li...4714e-97     309     38     55GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; ISS:PomBase.
GO:0019483; P:beta-alanine biosynthetic process; ISS:PomBase.::GO:0006081; P:cellular aldehyde metabolic process; IC:PomBase.::GO:0006598; P:polyamine catabolic process; ISS:PomBase.
18P40108    496   ALDH_DAVTA Aldehyde dehydrogenase OS=Davidiel...4894e-97     308     39     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
19P30837    517   AL1B1_HUMAN Aldehyde dehydrogenase X, mitocho...4886e-96     306     37     56GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
20Q5R6B5    517   AL1B1_PONAB Aldehyde dehydrogenase X, mitocho...4888e-96     306     37     56GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
21Q6GNL7    902   AL1L1_XENLA Cytosolic 10-formyltetrahydrofola...4801e-95     315     37     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016155; F:formyltetrahydrofolate dehydrogenase activity; IEA:EC.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0009258; P:10-formyltetrahydrofolate catabolic process; IEA:InterPro.::GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
22Q63ZT8    902   AL1L1_XENTR Cytosolic 10-formyltetrahydrofola...4801e-95     315     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016155; F:formyltetrahydrofolate dehydrogenase activity; IEA:EC.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0009258; P:10-formyltetrahydrofolate catabolic process; IEA:InterPro.::GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
23O94788    518   AL1A2_HUMAN Retinal dehydrogenase 2 OS=Homo s...4791e-94     303     38     55GO:0005634; C:nucleus; IDA:HPA.
GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; ISS:UniProtKB.::GO:0016918; F:retinal binding; ISS:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.
GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0021915; P:neural tube development; IMP:UniProtKB.::GO:0034097; P:response to cytokine stimulus; IDA:UniProtKB.
24Q62148    518   AL1A2_MOUSE Retinal dehydrogenase 2 OS=Mus mu...4796e-94     301     38     55
GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; IDA:MGI.::GO:0001758; F:retinal dehydrogenase activity; IDA:MGI.
GO:0042904; P:9-cis-retinoic acid biosynthetic process; IDA:MGI.::GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0001568; P:blood vessel development; IMP:MGI.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0031076; P:embryonic camera-type eye development; IGI:MGI.::GO:0048566; P:embryonic digestive tract development; IMP:MGI.::GO:0035115; P:embryonic forelimb morphogenesis; IMP:MGI.::GO:0060324; P:face development; IMP:MGI.::GO:0001947; P:heart looping; TAS:DFLAT.::GO:0030902; P:hindbrain development; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0016331; P:morphogenesis of embryonic epithelium; IMP:MGI.::GO:0014032; P:neural crest cell development; IMP:MGI.::GO:0030182; P:neuron differentiation; IMP:MGI.::GO:0031016; P:pancreas development; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0010628; P:positive regulation of gene expression; IMP:MGI.::GO:0009954; P:proximal/distal pattern formation; IMP:MGI.::GO:0001936; P:regulation of endothelial cell proliferation; IMP:MGI.::GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0048384; P:retinoic acid receptor signaling pathway; IMP:MGI.::GO:0035799; P:ureter maturation; IMP:MGI.
25Q66HF8    519   AL1B1_RAT Aldehyde dehydrogenase X, mitochond...4847e-94     301     37     56GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
26Q63639    518   AL1A2_RAT Retinal dehydrogenase 2 OS=Rattus n...4799e-94     300     37     55GO:0005829; C:cytosol; IDA:RGD.
GO:0016918; F:retinal binding; IDA:RGD.::GO:0001758; F:retinal dehydrogenase activity; IDA:RGD.
GO:0001822; P:kidney development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0007494; P:midgut development; IEP:RGD.::GO:0021983; P:pituitary gland development; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.
27B1Z033    489   BETB_BURA4 Betaine aldehyde dehydrogenase OS=...4752e-93     299     36     56
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
28O35945    501   AL1A7_MOUSE Aldehyde dehydrogenase, cytosolic...4752e-93     299     37     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
29Q0B712    489   BETB_BURCM Betaine aldehyde dehydrogenase OS=...4752e-93     299     36     56
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
30C3K3D2    490   BETB_PSEFS Betaine aldehyde dehydrogenase OS=...4754e-93     298     36     56
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
31Q9CZS1    519   AL1B1_MOUSE Aldehyde dehydrogenase X, mitocho...4847e-93     298     36     56GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
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