| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P47196 | 480 | AKT1_RAT RAC-alpha serine/threonine-protein k... | 338 | 8e-89 | 300 | 43 | 64 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007568; P:aging; IDA:RGD.::GO:0030030; P:cell projection organization; IDA:MGI.::GO:0071456; P:cellular response to hypoxia; IDA:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045792; P:negative regulation of cell size; IDA:MGI.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:RGD.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0030307; P:positive regulation of cell growth; IDA:RGD.::GO:0045907; P:positive regulation of vasoconstriction; IMP:RGD.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0006412; P:translation; IMP:UniProtKB. | 62 | P31750 | 480 | AKT1_MOUSE RAC-alpha serine/threonine-protein... | 338 | 9e-89 | 300 | 43 | 64 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0042640; P:anagen; IMP:MGI.::GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0015758; P:glucose transport; IMP:UniProtKB.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0060709; P:glycogen cell development involved in embryonic placenta development; IMP:MGI.::GO:0006954; P:inflammatory response; IDA:MGI.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.::GO:0001893; P:maternal placenta development; IMP:MGI.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0032287; P:peripheral nervous system myelin maintenance; IMP:MGI.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0010765; P:positive regulation of sodium ion transport; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0030163; P:protein catabolic process; IDA:MGI.::GO:0016567; P:protein ubiquitination; IDA:MGI.::GO:0010975; P:regulation of neuron projection development; IDA:UniProtKB.::GO:0045884; P:regulation of survival gene product expression; IDA:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0032094; P:response to food; IDA:MGI.::GO:0051146; P:striated muscle cell differentiation; IGI:MGI. | 63 | Q98TY9 | 481 | AKT1_XENLA RAC-alpha serine/threonine-protein... | 338 | 1e-88 | 300 | 43 | 63 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0015758; P:glucose transport; ISS:UniProtKB.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB. | 64 | Q9Y243 | 479 | AKT3_HUMAN RAC-gamma serine/threonine-protein... | 326 | 1e-88 | 300 | 42 | 65 | GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0000002; P:mitochondrial genome maintenance; IMP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB. | 65 | P31748 | 501 | AKT_MLVAT AKT kinase-transforming protein OS=... | 338 | 2e-88 | 300 | 43 | 64 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 66 | Q9WUA6 | 479 | AKT3_MOUSE RAC-gamma serine/threonine-protein... | 326 | 2e-88 | 300 | 42 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 67 | Q01314 | 480 | AKT1_BOVIN RAC-alpha serine/threonine-protein... | 338 | 3e-88 | 299 | 43 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 68 | Q63484 | 479 | AKT3_RAT RAC-gamma serine/threonine-protein k... | 326 | 8e-88 | 298 | 42 | 65 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; IMP:MGI.::GO:0010765; P:positive regulation of sodium ion transport; IMP:MGI. | 69 | P31749 | 480 | AKT1_HUMAN RAC-alpha serine/threonine-protein... | 316 | 8e-87 | 295 | 44 | 66 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0030235; F:nitric-oxide synthase regulator activity; IMP:BHF-UCL.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0006924; P:activation-induced cell death of T cells; IMP:MGI.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; TAS:UniProtKB.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0031999; P:negative regulation of fatty acid beta-oxidation; IMP:BHF-UCL.::GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.::GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0031659; P:positive regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.::GO:2001047; P:regulation of G1/S transition checkpoint; TAS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0034405; P:response to fluid shear stress; IMP:BHF-UCL.::GO:0009408; P:response to heat; TAS:ProtInc.::GO:0070141; P:response to UV-A; IDA:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 70 | P05128 | 682 | KPCG_BOVIN Protein kinase C gamma type OS=Bos... | 141 | 0.00000000002 | 71.6 | 32 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 71 | P90980 | 682 | KPC2_CAEEL Protein kinase C-like 2 OS=Caenorh... | 154 | 0.000000000002 | 75.5 | 31 | 47 | GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0043005; C:neuron projection; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 72 | P34722 | 704 | KPC1_CAEEL Protein kinase C-like 1 OS=Caenorh... | 239 | 3e-16 | 87.4 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0000003; P:reproduction; IMP:WormBase. | 73 | Q6P5Z2 | 889 | PKN3_HUMAN Serine/threonine-protein kinase N3... | 364 | 2e-86 | 305 | 45 | 63 | GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0010631; P:epithelial cell migration; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 74 | F1M7Y5 | 596 | KPCI_RAT Protein kinase C iota type OS=Rattus... | 69 | 0.004 | 45.1 | 36 | 52 | GO:0031252; C:cell leading edge; IDA:RGD.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0004697; F:protein kinase C activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; IMP:RGD.::GO:0034613; P:cellular protein localization; IMP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IMP:RGD.::GO:0048194; P:Golgi vesicle budding; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070555; P:response to interleukin-1; IMP:RGD. | 75 | Q62074 | 595 | KPCI_MOUSE Protein kinase C iota type OS=Mus ... | 69 | 0.004 | 45.1 | 36 | 52 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0045216; P:cell-cell junction organization; ISS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.::GO:0035089; P:establishment of apical/basal cell polarity; IMP:MGI.::GO:0042462; P:eye photoreceptor cell development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB. | 76 | P41743 | 596 | KPCI_HUMAN Protein kinase C iota type OS=Homo... | 69 | 0.003 | 45.1 | 36 | 52 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000133; C:polarisome; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:UniProtKB.::GO:0005543; F:phospholipid binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; TAS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; IMP:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.::GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0006612; P:protein targeting to membrane; NAS:UniProtKB.::GO:0046903; P:secretion; NAS:UniProtKB.::GO:0070830; P:tight junction assembly; TAS:Reactome. | 77 | Q5R4K9 | 596 | KPCI_PONAB Protein kinase C iota type OS=Pong... | 69 | 0.003 | 45.1 | 36 | 52 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB. | 78 | P63319 | 697 | KPCG_RAT Protein kinase C gamma type OS=Rattu... | 141 | 0.00000000002 | 71.6 | 32 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:RGD.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; NAS:RGD.::GO:0007611; P:learning or memory; IEP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:RGD. | 79 | P63318 | 697 | KPCG_MOUSE Protein kinase C gamma type OS=Mus... | 141 | 0.00000000002 | 71.6 | 32 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0097060; C:synaptic membrane; IDA:UniProtKB.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007635; P:chemosensory behavior; IMP:MGI.::GO:0060384; P:innervation; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; IMP:UniProtKB.::GO:0048265; P:response to pain; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; IMP:UniProtKB. | 80 | P05129 | 697 | KPCG_HUMAN Protein kinase C gamma type OS=Hom... | 141 | 0.00000000002 | 71.6 | 32 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0042177; P:negative regulation of protein catabolic process; IDA:HGNC.::GO:0031397; P:negative regulation of protein ubiquitination; IDA:HGNC.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032425; P:positive regulation of mismatch repair; IDA:HGNC.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 81 | P10829 | 697 | KPCG_RABIT Protein kinase C gamma type OS=Ory... | 141 | 0.00000000002 | 72 | 32 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 82 | Q90XF2 | 588 | KPCI_DANRE Protein kinase C iota type OS=Dani... | 69 | 0.002 | 45.8 | 36 | 51 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031226; C:intrinsic to plasma membrane; IDA:ZFIN.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005915; C:zonula adherens; IDA:ZFIN. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034334; P:adherens junction maintenance; IMP:ZFIN.::GO:0045217; P:cell-cell junction maintenance; IMP:ZFIN.::GO:0007502; P:digestive tract mesoderm development; IMP:ZFIN.::GO:0048546; P:digestive tract morphogenesis; IMP:ZFIN.::GO:0021744; P:dorsal motor nucleus of vagus nerve development; IMP:ZFIN.::GO:0035050; P:embryonic heart tube development; IMP:ZFIN.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:ZFIN.::GO:0016332; P:establishment or maintenance of polarity of embryonic epithelium; IMP:ZFIN.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IMP:ZFIN.::GO:0008078; P:mesodermal cell migration; IMP:ZFIN.::GO:0001738; P:morphogenesis of a polarized epithelium; IMP:ZFIN.::GO:0001841; P:neural tube formation; IGI:ZFIN.::GO:0007405; P:neuroblast proliferation; IMP:ZFIN.::GO:0007097; P:nuclear migration; IMP:ZFIN.::GO:0042476; P:odontogenesis; IMP:ZFIN.::GO:0060042; P:retina morphogenesis in camera-type eye; IMP:ZFIN. | 83 | P13677 | 700 | KPC2_DROME Protein kinase C, eye isozyme OS=D... | 153 | 0.000000000000004 | 84 | 34 | 50 | GO:0016027; C:inaD signaling complex; TAS:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016062; P:adaptation of rhodopsin mediated signaling; IMP:FlyBase.::GO:0019722; P:calcium-mediated signaling; TAS:FlyBase.::GO:0006928; P:cellular component movement; IMP:FlyBase.::GO:0016059; P:deactivation of rhodopsin mediated signaling; IMP:FlyBase.::GO:0008585; P:female gonad development; IMP:FlyBase.::GO:0030845; P:inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045471; P:response to ethanol; IDA:FlyBase. | 84 | Q4R4U2 | 697 | KPCG_MACFA Protein kinase C gamma type OS=Mac... | 141 | 0.00000000002 | 71.6 | 32 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 85 | P54644 | 444 | KRAC_DICDI RAC family serine/threonine-protei... | 340 | 7e-83 | 282 | 41 | 65 | GO:0005938; C:cell cortex; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0019887; F:protein kinase regulator activity; TAS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; TAS:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:dictyBase.::GO:0031036; P:myosin II filament assembly; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0045859; P:regulation of protein kinase activity; TAS:dictyBase. | 86 | Q19266 | 597 | KPC3_CAEEL Protein kinase C-like 3 OS=Caenorh... | 69 | 0.0007 | 47.4 | 35 | 54 | GO:0016324; C:apical plasma membrane; IDA:WormBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW. | 87 | A8WUG4 | 597 | KPC3_CAEBR Protein kinase C-like 3 OS=Caenorh... | 69 | 0.0008 | 47.4 | 35 | 54 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007163; P:establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW. | 88 | Q06226 | 430 | SGK1_RAT Serine/threonine-protein kinase Sgk1... | 332 | 2e-80 | 275 | 42 | 63 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043423; F:3-phosphoinositide-dependent protein kinase binding; IPI:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IPI:RGD.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0048156; F:tau protein binding; IPI:RGD. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0032869; P:cellular response to insulin stimulus; IMP:MGI.::GO:0006883; P:cellular sodium ion homeostasis; IDA:RGD.::GO:0043402; P:glucocorticoid mediated signaling pathway; IMP:RGD.::GO:0007616; P:long-term memory; IMP:RGD.::GO:0007019; P:microtubule depolymerization; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0031115; P:negative regulation of microtubule polymerization; IDA:RGD.::GO:0048812; P:neuron projection morphogenesis; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0030307; P:positive regulation of cell growth; IDA:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0010765; P:positive regulation of sodium ion transport; IMP:MGI.::GO:0051726; P:regulation of cell cycle; IMP:RGD.::GO:0032880; P:regulation of protein localization; IMP:MGI.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0008542; P:visual learning; IMP:RGD. | 89 | Q6U1I9 | 432 | SGK1_CHICK Serine/threonine-protein kinase Sg... | 332 | 7e-80 | 273 | 42 | 62 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 90 | O00141 | 431 | SGK1_HUMAN Serine/threonine-protein kinase Sg... | 332 | 2e-79 | 272 | 42 | 62 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; TAS:UniProtKB.::GO:0017081; F:chloride channel regulator activity; TAS:UniProtKB.::GO:0015459; F:potassium channel regulator activity; TAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0017080; F:sodium channel regulator activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; TAS:UniProtKB.::GO:0032411; P:positive regulation of transporter activity; TAS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0008217; P:regulation of blood pressure; TAS:UniProtKB.::GO:0050790; P:regulation of catalytic activity; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0060453; P:regulation of gastric acid secretion; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0070294; P:renal sodium ion absorption; TAS:UniProtKB.::GO:0006950; P:response to stress; TAS:ProtInc. | 91 | Q9WVC6 | 431 | SGK1_MOUSE Serine/threonine-protein kinase Sg... | 332 | 2e-79 | 272 | 42 | 62 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IDA:MGI. |
