Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBL088C
Length:
2787
Number of sequences:
5887
Description:
YBL088C TEL1 SGDID:S000000184, Chr II from 59382-51019, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q6FX42    2379   ATR_CANGA Serine/threonine-protein kinase MEC...3565e-47     191     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
32P32600    2474   TOR2_YEAST Serine/threonine-protein kinase TO...3697e-46     187     34     50GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.::GO:0031932; C:TORC2 complex; IPI:SGD.
GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:SGD.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:SGD.::GO:0010507; P:negative regulation of autophagy; IGI:SGD.::GO:0045807; P:positive regulation of endocytosis; IMP:SGD.::GO:0051726; P:regulation of cell cycle; TAS:SGD.::GO:0001558; P:regulation of cell growth; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; IMP:SGD.::GO:0042254; P:ribosome biogenesis; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.
33Q75DB8    2324   ATR_ASHGO Serine/threonine-protein kinase MEC...3542e-45     186     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
34Q6CT34    2287   ATR_KLULA Serine/threonine-protein kinase MEC...3493e-45     185     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
35Q9VXG8    2517   ATR_DROME Serine/threonine-protein kinase ATR...5903e-45     185     27     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0030261; P:chromosome condensation; IGI:FlyBase.::GO:0000076; P:DNA replication checkpoint; IMP:FlyBase.::GO:0045002; P:double-strand break repair via single-strand annealing; IMP:FlyBase.::GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; TAS:FlyBase.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007444; P:imaginal disc development; TAS:FlyBase.::GO:0007133; P:meiotic anaphase I; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0007348; P:regulation of syncytial blastoderm mitotic cell cycle; TAS:FlyBase.::GO:0009314; P:response to radiation; TAS:FlyBase.::GO:0000723; P:telomere maintenance; IGI:FlyBase.
36Q9FKS4    2702   ATR_ARATH Serine/threonine-protein kinase ATR...6031e-44     183     25     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IGI:TAIR.::GO:0007126; P:meiosis; IGI:TAIR.::GO:0032504; P:multicellular organism reproduction; IGI:TAIR.::GO:0032204; P:regulation of telomere maintenance; IGI:TAIR.::GO:0010044; P:response to aluminum ion; IMP:TAIR.::GO:0010332; P:response to gamma radiation; IMP:TAIR.::GO:0043247; P:telomere maintenance in response to DNA damage; TAS:TAIR.::GO:0007004; P:telomere maintenance via telomerase; IMP:TAIR.
37P35169    2470   TOR1_YEAST Serine/threonine-protein kinase TO...3686e-43     177     33     48GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0000080; P:G1 phase of mitotic cell cycle; IMP:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:SGD.::GO:0010507; P:negative regulation of autophagy; IGI:SGD.::GO:0051726; P:regulation of cell cycle; IMP:SGD.::GO:0001558; P:regulation of cell growth; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.::GO:0042254; P:ribosome biogenesis; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.::GO:0042790; P:transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IMP:SGD.
38O14356    2335   TOR1_SCHPO Phosphatidylinositol 3-kinase tor1...3691e-42     176     30     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007569; P:cell aging; TAS:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; IMP:PomBase.::GO:0043091; P:L-arginine import; IMP:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:PomBase.::GO:0060357; P:regulation of leucine import; IMP:PomBase.::GO:0009266; P:response to temperature stimulus; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
39Q9VK45    2470   TOR_DROME Target of rapamycin OS=Drosophila m...3826e-42     174     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; NAS:FlyBase.::GO:0043621; F:protein self-association; IDA:FlyBase.
GO:0006914; P:autophagy; IMP:FlyBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0009594; P:detection of nutrient; TAS:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0032456; P:endocytic recycling; IDA:FlyBase.::GO:0008406; P:gonad development; IMP:FlyBase.::GO:0035264; P:multicellular organism growth; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; NAS:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; TAS:FlyBase.::GO:0046622; P:positive regulation of organ growth; TAS:FlyBase.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:FlyBase.::GO:0090070; P:positive regulation of ribosome biogenesis; IMP:FlyBase.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IGI:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.
40Q0DJS1    2465   TOR_ORYSJ Serine/threonine-protein kinase TOR...4186e-42     174     30     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
41Q8SSE7    1935   ATR_ENCCU Probable serine/threonine-protein k...6232e-41     173     26     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
42P42346    2549   MTOR_RAT Serine/threonine-protein kinase mTOR...3825e-40     168     31     48GO:0005829; C:cytosol; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0070438; C:mTOR-FKBP12-rapamycin complex; IDA:RGD.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031931; C:TORC1 complex; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:RGD.::GO:0045792; P:negative regulation of cell size; IMP:MGI.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:RGD.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IMP:RGD.::GO:0043610; P:regulation of carbohydrate utilization; IDA:RGD.::GO:0031998; P:regulation of fatty acid beta-oxidation; IDA:RGD.::GO:0005979; P:regulation of glycogen biosynthetic process; IDA:RGD.::GO:0032095; P:regulation of response to food; IDA:RGD.
43P42345    2549   MTOR_HUMAN Serine/threonine-protein kinase mT...3829e-40     167     31     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0031931; C:TORC1 complex; IDA:UniProtKB.::GO:0031932; C:TORC2 complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.::GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.::GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.::GO:0001156; F:TFIIIC-class transcription factor binding; IDA:UniProtKB.
GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0030163; P:protein catabolic process; TAS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IDA:UniProtKB.::GO:0007584; P:response to nutrient; NAS:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB.
44Q9JLN9    2549   MTOR_MOUSE Serine/threonine-protein kinase mT...3821e-39     167     31     48GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0043022; F:ribosome binding; IDA:UniProtKB.
GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; IDA:UniProtKB.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0045792; P:negative regulation of cell size; IGI:MGI.::GO:0016242; P:negative regulation of macroautophagy; IMP:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.::GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:MGI.::GO:0045859; P:regulation of protein kinase activity; IGI:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI.::GO:0043200; P:response to amino acid stimulus; IDA:MGI.::GO:0032868; P:response to insulin stimulus; IDA:MGI.::GO:0031529; P:ruffle organization; IDA:MGI.
45Q9Y7K2    2337   TOR2_SCHPO Phosphatidylinositol 3-kinase tor2...3752e-39     166     31     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0034064; C:Tor2-Mei2-Ste11 complex; IDA:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030996; P:cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0031670; P:cellular response to nutrient; NAS:PomBase.::GO:0010507; P:negative regulation of autophagy; IMP:PomBase.::GO:0010503; P:negative regulation of cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0010515; P:negative regulation of induction of conjugation with cellular fusion; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
46Q8BKX6    3658   SMG1_MOUSE Serine/threonine-protein kinase SM...3225e-38     162     32     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
47Q96Q15    3661   SMG1_HUMAN Serine/threonine-protein kinase SM...3226e-38     161     32     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:UniProtKB.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
48Q95Q95    2697   TOR_CAEEL Target of rapamycin homolog OS=Caen...3547e-38     161     31     50GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
GO:0000492; P:box C/D snoRNP assembly; IMP:WormBase.::GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006629; P:lipid metabolic process; IMP:WormBase.::GO:0045727; P:positive regulation of translation; IMP:WormBase.::GO:0009408; P:response to heat; IMP:WormBase.::GO:0031929; P:TOR signaling cascade; IMP:WormBase.::GO:0006412; P:translation; IMP:WormBase.
49Q9FR53    2481   TOR_ARATH Serine/threonine-protein kinase TOR...700.054     43.1     37     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0043621; F:protein self-association; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000975; F:regulatory region DNA binding; IDA:UniProtKB.
GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0010507; P:negative regulation of autophagy; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IGI:UniProtKB.::GO:0040019; P:positive regulation of embryonic development; IMP:UniProtKB.::GO:2000234; P:positive regulation of rRNA processing; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0009303; P:rRNA transcription; IMP:TAIR.
50Q22258    2531   ATR_CAEEL Serine/threonine-protein kinase ATR...5476e-36     154     25     44GO:0000794; C:condensed nuclear chromosome; TAS:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.
51Q86C65    2380   TOR_DICDI Target of rapamycin OS=Dictyosteliu...4151e-35     154     30     45GO:0031932; C:TORC2 complex; IPI:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
52Q61CW2    2313   SMG1_CAEBR Serine/threonine-protein kinase sm...3175e-32     142     32     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
53O01510    2322   SMG1_CAEEL Serine/threonine-protein kinase sm...2938e-31     137     32     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IGI:WormBase.
54Q70PP2    3218   SMG1_DROME Serine/threonine-protein kinase Sm...3061e-30     137     28     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0050808; P:synapse organization; IDA:FlyBase.::GO:0048489; P:synaptic vesicle transport; IDA:FlyBase.
55P97313    4128   PRKDC_MOUSE DNA-dependent protein kinase cata...4899e-28     128     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0002326; P:B cell lineage commitment; IMP:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.::GO:0035234; P:germ cell programmed cell death; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0033152; P:immunoglobulin V(D)J recombination; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0002328; P:pro-B cell differentiation; IMP:MGI.::GO:0031648; P:protein destabilization; IDA:MGI.::GO:0010332; P:response to gamma radiation; IMP:MGI.::GO:0001756; P:somitogenesis; IGI:MGI.::GO:0033077; P:T cell differentiation in thymus; IMP:MGI.::GO:0002360; P:T cell lineage commitment; IMP:MGI.::GO:0033153; P:T cell receptor V(D)J recombination; IMP:MGI.::GO:0000723; P:telomere maintenance; IMP:MGI.
56Q9DEI1    4146   PRKDC_XENLA DNA-dependent protein kinase cata...4641e-25     121     25     42GO:0070419; C:nonhomologous end joining complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004677; F:DNA-dependent protein kinase activity; IEA:InterPro.
GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
57P78527    4128   PRKDC_HUMAN DNA-dependent protein kinase cata...4632e-24     117     25     41GO:0005958; C:DNA-dependent protein kinase-DNA ligase 4 complex; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004677; F:DNA-dependent protein kinase activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.::GO:0006303; P:double-strand break repair via nonhomologous end joining; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
58Q553E9    2344   SMG1_DICDI Probable serine/threonine-protein ...920.004     46.6     33     51
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
59Q8QGX4    4134   PRKDC_CHICK DNA-dependent protein kinase cata...4651e-23     114     25     41GO:0070419; C:nonhomologous end joining complex; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004677; F:DNA-dependent protein kinase activity; IEA:InterPro.
GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0006303; P:double-strand break repair via nonhomologous end joining; TAS:Reactome.
60Q54UC0    4299   PRKDC_DICDI DNA-dependent protein kinase cata...3899e-23     111     25     43GO:0005958; C:DNA-dependent protein kinase-DNA ligase 4 complex; ISS:dictyBase.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004677; F:DNA-dependent protein kinase activity; IEA:InterPro.
GO:0006975; P:DNA damage induced protein phosphorylation; IMP:dictyBase.::GO:0006310; P:DNA recombination; ISS:dictyBase.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
61Q8WN22    4144   PRKDC_CANFA DNA-dependent protein kinase cata...320.53     39.7     53     72
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
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