rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P38041 | 980 | BOB1_YEAST Protein BOB1 OS=Saccharomyces cere... | 980 | 0 | 2013 | 100 | 100 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007118; P:budding cell apical bud growth; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD. | 2 | P39969 | 1040 | BOI2_YEAST Protein BOI2 OS=Saccharomyces cere... | 217 | 2e-89 | 313 | 68 | 81 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007118; P:budding cell apical bud growth; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD. | 3 | O74653 | 871 | POB1_SCHPO Protein pob1 OS=Schizosaccharomyce... | 81 | 0.00000004 | 60.8 | 40 | 58 | GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0000920; P:cytokinetic cell separation; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase. | 4 | Q8WWN9 | 437 | ICEF1_HUMAN Interactor protein for cytohesin ... | 157 | 0.000000005 | 63.2 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005344; F:oxygen transporter activity; NAS:UniProtKB.::GO:0004601; F:peroxidase activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006979; P:response to oxidative stress; ISS:UniProtKB. | 5 | Q5DU31 | 406 | ICEF1_MOUSE Interactor protein for cytohesin ... | 128 | 0.0000001 | 58.5 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 6 | Q80VL0 | 406 | ICEF1_RAT Interactor protein for cytohesin ex... | 131 | 0.000001 | 55.5 | 31 | 42 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IPI:RGD. | | | | | | | | | | GO:0033126; P:positive regulation of GTP catabolic process; IDA:RGD. | 7 | Q86IV4 | 458 | Y4775_DICDI PH domain-containing protein DDB_... | 117 | 0.000003 | 54.7 | 26 | 47 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 8 | Q9Z1T4 | 1032 | CNKR2_RAT Connector enhancer of kinase suppre... | 149 | 0.000004 | 54.7 | 30 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IDA:RGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 9 | Q80YA9 | 1032 | CNKR2_MOUSE Connector enhancer of kinase supp... | 128 | 0.000005 | 54.3 | 31 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 10 | Q8WXI2 | 1034 | CNKR2_HUMAN Connector enhancer of kinase supp... | 128 | 0.000005 | 54.3 | 31 | 41 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 11 | Q3UIL6 | 1118 | PKHA7_MOUSE Pleckstrin homology domain-contai... | 115 | 0.000008 | 53.5 | 25 | 50 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005915; C:zonula adherens; ISS:UniProtKB. | | | | | | | | | | GO:0070097; F:delta-catenin binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0090136; P:epithelial cell-cell adhesion; ISS:UniProtKB.::GO:0045218; P:zonula adherens maintenance; ISS:UniProtKB. | 12 | Q6IQ23 | 1121 | PKHA7_HUMAN Pleckstrin homology domain-contai... | 115 | 0.000009 | 53.5 | 25 | 50 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005915; C:zonula adherens; IDA:UniProtKB. | | | | | | | | | | GO:0070097; F:delta-catenin binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0090136; P:epithelial cell-cell adhesion; IMP:UniProtKB.::GO:0045218; P:zonula adherens maintenance; IMP:UniProtKB. | 13 | B6RSP1 | 1197 | PKHA7_DANRE Pleckstrin homology domain-contai... | 115 | 0.00001 | 52.8 | 23 | 46 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005915; C:zonula adherens; ISS:UniProtKB. | | | | | | | | | | GO:0070097; F:delta-catenin binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0090136; P:epithelial cell-cell adhesion; ISS:UniProtKB.::GO:0045218; P:zonula adherens maintenance; ISS:UniProtKB. | 14 | Q9HAU0 | 1116 | PKHA5_HUMAN Pleckstrin homology domain-contai... | 115 | 0.00002 | 52.4 | 28 | 45 | | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 15 | Q5U2Z7 | 748 | RHG24_RAT Rho GTPase-activating protein 24 OS... | 118 | 0.00004 | 51.2 | 25 | 48 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 16 | Q7Z5H3 | 698 | RHG22_HUMAN Rho GTPase-activating protein 22 ... | 113 | 0.0001 | 50.1 | 27 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q969H4 | 720 | CNKR1_HUMAN Connector enhancer of kinase supp... | 148 | 0.0001 | 49.7 | 26 | 42 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0005911; C:cell-cell junction; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IDA:MGI. | | | | | | | | | | GO:0007266; P:Rho protein signal transduction; IPI:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc. | 18 | Q8C4V1 | 747 | RHG24_MOUSE Rho GTPase-activating protein 24 ... | 113 | 0.0001 | 49.7 | 25 | 49 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 19 | Q8BZT2 | 735 | SH3R2_MOUSE Putative E3 ubiquitin-protein lig... | 53 | 0.0003 | 48.5 | 34 | 66 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 20 | Q8N264 | 748 | RHG24_HUMAN Rho GTPase-activating protein 24 ... | 118 | 0.0003 | 48.5 | 25 | 47 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 21 | O43739 | 400 | CYH3_HUMAN Cytohesin-3 OS=Homo sapiens (Human... | 44 | 0.0004 | 47.8 | 45 | 61 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; TAS:ProtInc.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; TAS:ProtInc. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc. | 22 | P97696 | 400 | CYH3_RAT Cytohesin-3 OS=Rattus norvegicus (Ra... | 44 | 0.0004 | 47.8 | 45 | 61 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 23 | Q15438 | 398 | CYH1_HUMAN Cytohesin-1 OS=Homo sapiens (Human... | 44 | 0.0004 | 47.4 | 45 | 61 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IDA:MGI.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc. | 24 | Q76MZ1 | 398 | CYH1_CHLAE Cytohesin-1 OS=Chlorocebus aethiop... | 44 | 0.0004 | 47.4 | 45 | 61 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 25 | Q99418 | 400 | CYH2_HUMAN Cytohesin-2 OS=Homo sapiens (Human... | 44 | 0.0004 | 47.4 | 45 | 61 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0006897; P:endocytosis; TAS:ProtInc.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome. | 26 | P63035 | 400 | CYH2_RAT Cytohesin-2 OS=Rattus norvegicus (Ra... | 44 | 0.0004 | 47.4 | 45 | 61 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0016358; P:dendrite development; TAS:RGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome. | 27 | P97694 | 398 | CYH1_RAT Cytohesin-1 OS=Rattus norvegicus (Ra... | 44 | 0.0004 | 47.4 | 45 | 61 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome. | 28 | Q9QX11 | 398 | CYH1_MOUSE Cytohesin-1 OS=Mus musculus (Mouse... | 44 | 0.0004 | 47.4 | 45 | 61 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005923; C:tight junction; IDA:MGI. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome. | 29 | Q6IDD9 | 1360 | SARM1_DROME Sterile alpha and TIR motif-conta... | 153 | 0.0006 | 47.4 | 27 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 30 | Q8BL80 | 702 | RHG22_MOUSE Rho GTPase-activating protein 22 ... | 114 | 0.0007 | 47 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 31 | Q54KA7 | 986 | SECG_DICDI Ankyrin repeat, PH and SEC7 domain... | 117 | 0.0008 | 47.4 | 26 | 43 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. |