Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBL085W
Length:
980
Number of sequences:
5887
Description:
YBL085W BOI1 SGDID:S000000181, Chr II from 63876-66818, Genome Release 64-1-1, Verified ORF, "Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q99MZ8    263   LASP1_RAT LIM and SH3 domain protein 1 OS=Rat...750.008     42.7     35     53GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB.
GO:0015075; F:ion transmembrane transporter activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
62Q76MY7    399   CYH2_CHLAE Cytohesin-2 OS=Chlorocebus aethiop...440.008     43.5     45     61GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
63Q9H4M7    779   PKHA4_HUMAN Pleckstrin homology domain-contai...1200.008     43.9     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB.
64Q61792    263   LASP1_MOUSE LIM and SH3 domain protein 1 OS=M...750.009     42.7     35     53GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
65Q9UN19    280   DAPP1_HUMAN Dual adapter for phosphotyrosine ...1170.009     42.7     30     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; NAS:UniProtKB.
GO:0007165; P:signal transduction; TAS:ProtInc.
66Q5R5W0    261   LASP1_PONAB LIM and SH3 domain protein 1 OS=P...750.009     42.7     35     53GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
67Q9BX66    1292   SRBS1_HUMAN Sorbin and SH3 domain-containing ...600.01     43.5     32     58GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB.::GO:0005915; C:zonula adherens; TAS:ProtInc.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005158; F:insulin receptor binding; IDA:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; ISS:BHF-UCL.
GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0015758; P:glucose transport; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:BHF-UCL.::GO:0043149; P:stress fiber assembly; ISS:UniProtKB.
68Q14847    261   LASP1_HUMAN LIM and SH3 domain protein 1 OS=H...750.01     42.4     35     53GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.
GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
69Q9UIA0    394   CYH4_HUMAN Cytohesin-4 OS=Homo sapiens (Human...440.012     42.7     45     61GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
70Q62417    1290   SRBS1_MOUSE Sorbin and SH3 domain-containing ...600.013     43.1     30     58GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB.
GO:0005158; F:insulin receptor binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL.
GO:0048041; P:focal adhesion assembly; IDA:UniProtKB.::GO:0015758; P:glucose transport; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.::GO:0043149; P:stress fiber assembly; IDA:UniProtKB.
71Q8K3E5    1047   AHI1_MOUSE Jouberin OS=Mus musculus (Mouse). ...690.013     43.1     32     54GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0036038; C:TCTN-B9D complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0035844; P:cloaca development; IGI:UniProtKB.::GO:0001947; P:heart looping; IGI:UniProtKB.::GO:0030902; P:hindbrain development; IGI:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0071599; P:otic vesicle development; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; IMP:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; IGI:UniProtKB.::GO:0033365; P:protein localization to organelle; IMP:UniProtKB.::GO:0050795; P:regulation of behavior; IMP:UniProtKB.::GO:0010842; P:retina layer formation; IGI:UniProtKB.::GO:0065001; P:specification of axis polarity; IGI:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IMP:UniProtKB.
72Q8TD55    490   PKHO2_HUMAN Pleckstrin homology domain-contai...550.013     42.7     33     51
GO:0005543; F:phospholipid binding; IEA:InterPro.
73Q3B7M5    260   LASP1_BOVIN LIM and SH3 domain protein 1 OS=B...740.014     42     35     53GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
74Q9ERE9    830   JIP2_MOUSE C-Jun-amino-terminal kinase-intera...560.014     43.1     34     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0014069; C:postsynaptic density; IDA:BHF-UCL.
GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0001662; P:behavioral fear response; IMP:BHF-UCL.::GO:0048813; P:dendrite morphogenesis; IMP:BHF-UCL.::GO:0007254; P:JNK cascade; IDA:MGI.::GO:0007617; P:mating behavior; IMP:BHF-UCL.::GO:0046958; P:nonassociative learning; IMP:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IMP:BHF-UCL.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IMP:BHF-UCL.::GO:0051966; P:regulation of synaptic transmission, glutamatergic; IMP:BHF-UCL.::GO:0035176; P:social behavior; IMP:BHF-UCL.
75Q8K124    495   PKHO2_MOUSE Pleckstrin homology domain-contai...420.014     42.7     36     60
GO:0005543; F:phospholipid binding; IEA:InterPro.
76Q86I31    885   GACFF_DICDI Rho GTPase-activating protein gac...1160.015     43.1     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
77Q80YW0    393   CYH4_MOUSE Cytohesin-4 OS=Mus musculus (Mouse...440.016     42.4     45     61GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
78Q13387    824   JIP2_HUMAN C-Jun-amino-terminal kinase-intera...560.018     42.7     34     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.
GO:0001540; F:beta-amyloid binding; NAS:UniProtKB.::GO:0019894; F:kinesin binding; ISS:UniProtKB.::GO:0005078; F:MAP-kinase scaffold activity; NAS:UniProtKB.::GO:0030295; F:protein kinase activator activity; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0001662; P:behavioral fear response; ISS:BHF-UCL.::GO:0048813; P:dendrite morphogenesis; ISS:BHF-UCL.::GO:0000165; P:MAPK cascade; IDA:MGI.::GO:0046958; P:nonassociative learning; ISS:BHF-UCL.::GO:0045768; P:positive regulation of anti-apoptosis; NAS:UniProtKB.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0051966; P:regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0035176; P:social behavior; ISS:BHF-UCL.
79Q8TEJ3    882   SH3R3_HUMAN SH3 domain-containing RING finger...561.1     37     34     46
GO:0008270; F:zinc ion binding; IEA:InterPro.
80Q559T8    2102   Y0701_DICDI Probable serine/threonine-protein...1230.023     42.4     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007154; P:cell communication; IEA:InterPro.
81O77506    263   LASP1_RABIT LIM and SH3 domain protein 1 OS=O...670.027     41.2     37     52GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
82Q60437    521   BAIP2_CRIGR Brain-specific angiogenesis inhib...720.029     42     35     53GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0009617; P:response to bacterium; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
83Q6NRD3    826   SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF...581.4     36.6     33     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
84Q6DTM3    1047   AHI1_RAT Jouberin OS=Rattus norvegicus (Rat)....690.032     42     32     52GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0036038; C:TCTN-B9D complex; ISS:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0035844; P:cloaca development; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0071599; P:otic vesicle development; ISS:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; ISS:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; ISS:UniProtKB.::GO:0050795; P:regulation of behavior; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0065001; P:specification of axis polarity; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
85Q6GMN2    535   BAIP2_RAT Brain-specific angiogenesis inhibit...720.032     41.6     35     53GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0009617; P:response to bacterium; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
86Q8BKX1    535   BAIP2_MOUSE Brain-specific angiogenesis inhib...720.033     41.6     35     53GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0051017; P:actin filament bundle assembly; IGI:MGI.::GO:0016358; P:dendrite development; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0048167; P:regulation of synaptic plasticity; IMP:MGI.::GO:0009617; P:response to bacterium; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:MGI.
87Q9UQB8    552   BAIP2_HUMAN Brain-specific angiogenesis inhib...720.033     41.6     35     53GO:0030054; C:cell junction; IDA:HPA.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.::GO:0070064; F:proline-rich region binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0007409; P:axonogenesis; TAS:ProtInc.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.::GO:0009617; P:response to bacterium; IMP:UniProtKB.
88Q8C120    878   SH3R3_MOUSE SH3 domain-containing RING finger...561.6     36.2     32     48
GO:0008270; F:zinc ion binding; IEA:InterPro.
89Q28E95    861   SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF...580.45     38.1     34     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
90Q7T2V3    1005   M3K10_XENLA Mitogen-activated protein kinase ...1250.048     41.2     23     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.
GO:0071570; P:cement gland development; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0048793; P:pronephros development; IMP:UniProtKB.
91Q5EAD0    521   BAIP2_BOVIN Brain-specific angiogenesis inhib...720.05     41.2     35     53GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0009617; P:response to bacterium; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
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