rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | B6HTQ4 | 439 | AMP2A_PENCW Methionine aminopeptidase 2 homol... | 212 | 3.4 | 35 | 22 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008235; F:metalloexopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0009987; P:cellular process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 182 | Q96MF2 | 364 | STAC3_HUMAN SH3 and cysteine-rich domain-cont... | 76 | 3.6 | 35 | 28 | 51 | | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 183 | Q6EV76 | 575 | FUT8_RAT Alpha-(1,6)-fucosyltransferase OS=Ra... | 51 | 3.6 | 35 | 39 | 59 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro. | 184 | Q8BGG7 | 638 | UBS3B_MOUSE Ubiquitin-associated and SH3 doma... | 50 | 3.7 | 35 | 36 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 185 | O75689 | 374 | ADAP1_HUMAN Arf-GAP with dual PH domain-conta... | 118 | 3.7 | 34.7 | 25 | 38 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; TAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 186 | P79282 | 575 | FUT8_PIG Alpha-(1,6)-fucosyltransferase OS=Su... | 51 | 3.8 | 35 | 39 | 55 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro. | 187 | Q8WZ64 | 1704 | ARAP2_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 114 | 3.9 | 35 | 21 | 39 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 188 | Q8XK20 | 568 | Y1583_CLOPE Putative ABC transporter ATP-bind... | 62 | 4 | 35 | 37 | 52 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro. | | | | | | | | | | | 189 | Q8BZ71 | 360 | STAC3_MOUSE SH3 and cysteine-rich domain-cont... | 76 | 4 | 34.7 | 28 | 51 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 190 | Q7SYB5 | 612 | DEFI6_DANRE Differentially expressed in FDCP ... | 97 | 4.1 | 35 | 31 | 45 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042074; P:cell migration involved in gastrulation; IMP:ZFIN.::GO:0060027; P:convergent extension involved in gastrulation; IMP:ZFIN. | 191 | Q5PXS1 | 509 | LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotu... | 65 | 4.4 | 34.7 | 26 | 54 | GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB. | 192 | O13154 | 448 | PACN2_CHICK Protein kinase C and casein kinas... | 56 | 4.4 | 34.7 | 36 | 57 | GO:0005829; C:cytosol; ISS:AgBase.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; ISS:AgBase. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; ISS:AgBase. | 193 | Q08DN7 | 844 | VAV_BOVIN Proto-oncogene vav OS=Bos taurus (B... | 70 | 4.6 | 34.7 | 27 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 194 | Q8BZ05 | 1703 | ARAP2_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 114 | 4.7 | 35 | 21 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 195 | Q9Y3Z3 | 626 | SAMH1_HUMAN SAM domain and HD domain-containi... | 72 | 4.8 | 34.7 | 26 | 56 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro. | | | | | | | | | | GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045088; P:regulation of innate immune response; IMP:UniProtKB. | 196 | Q9ULM0 | 1364 | PKHH1_HUMAN Pleckstrin homology domain-contai... | 164 | 5 | 34.7 | 21 | 47 | GO:0005856; C:cytoskeleton; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 197 | Q06449 | 215 | PIN3_YEAST [PSI+] inducibility protein 3 OS=S... | 55 | 5.1 | 33.9 | 33 | 60 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:SGD. | 198 | P50735 | 427 | GUDB_BACSU NAD-specific glutamate dehydrogena... | 56 | 5.1 | 34.3 | 34 | 54 | | | | | | | | | | | GO:0004352; F:glutamate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. | 199 | Q05876 | 534 | FYN_CHICK Tyrosine-protein kinase Fyn OS=Gall... | 61 | 5.2 | 34.7 | 30 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0015631; F:tubulin binding; ISS:AgBase. | | | | | | | | | | GO:0030900; P:forebrain development; ISS:AgBase.::GO:0001764; P:neuron migration; ISS:AgBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:AgBase.::GO:0008360; P:regulation of cell shape; ISS:AgBase. | 200 | P11710 | 512 | FUS1_YEAST Nuclear fusion protein FUS1 OS=Sac... | 57 | 5.3 | 34.7 | 26 | 51 | GO:0005938; C:cell cortex; IMP:GOC.::GO:0005887; C:integral to plasma membrane; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032065; P:cortical protein anchoring; IMP:SGD.::GO:0000755; P:cytogamy; IMP:SGD.::GO:0031385; P:regulation of termination of mating projection growth; IMP:SGD. | 201 | O42287 | 1270 | ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (... | 69 | 5.6 | 34.7 | 29 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 202 | Q8N8I0 | 201 | SAM12_HUMAN Sterile alpha motif domain-contai... | 109 | 6.2 | 33.5 | 22 | 50 | | | | | | | | | | | | | | | | | | | | | | 203 | Q80TI1 | 1356 | PKHH1_MOUSE Pleckstrin homology domain-contai... | 49 | 6.5 | 34.3 | 33 | 63 | GO:0005856; C:cytoskeleton; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 204 | Q01621 | 509 | LCK_RAT Proto-oncogene tyrosine-protein kinas... | 65 | 6.6 | 34.3 | 26 | 52 | GO:0030139; C:endocytic vesicle; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0003823; F:antigen binding; IPI:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0032403; F:protein complex binding; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006915; P:apoptotic process; IEP:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD.::GO:0070474; P:positive regulation of uterine smooth muscle contraction; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0042542; P:response to hydrogen peroxide; IDA:RGD.::GO:0009612; P:response to mechanical stimulus; IMP:RGD.::GO:0010043; P:response to zinc ion; IEP:RGD. | 205 | P27447 | 544 | YES_XIPHE Tyrosine-protein kinase Yes OS=Xiph... | 54 | 6.8 | 34.3 | 28 | 57 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 206 | P06240 | 509 | LCK_MOUSE Proto-oncogene tyrosine-protein kin... | 65 | 6.9 | 34.3 | 26 | 52 | GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IDA:MGI.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IMP:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0050856; P:regulation of T cell receptor signaling pathway; IDA:MGI.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB. | 207 | O14302 | 886 | CYK3_SCHPO cytokinesis protein 3 OS=Schizosac... | 67 | 7 | 34.3 | 27 | 51 | GO:0005826; C:actomyosin contractile ring; NAS:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0033205; P:cell cycle cytokinesis; NAS:PomBase. | 208 | P06239 | 509 | LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo... | 65 | 7.1 | 33.9 | 26 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0042609; F:CD4 receptor binding; IPI:UniProtKB.::GO:0042610; F:CD8 receptor binding; IPI:UniProtKB.::GO:0001948; F:glycoprotein binding; IPI:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; IEP:UniProtKB.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050862; P:positive regulation of T cell receptor signaling pathway; NAS:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0030217; P:T cell differentiation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 209 | Q8K298 | 1121 | ANLN_MOUSE Actin-binding protein anillin OS=M... | 120 | 7.3 | 34.3 | 20 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 210 | Q95KR7 | 509 | LCK_SAISC Proto-oncogene tyrosine-protein kin... | 65 | 7.3 | 33.9 | 26 | 52 | GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB. | 211 | Q5RDW3 | 201 | SAM12_PONAB Sterile alpha motif domain-contai... | 109 | 7.7 | 33.1 | 22 | 50 | | | | | | | | | | | | | | | | | | | | | |