Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBL056W
Length:
468
Number of sequences:
5887
Description:
YBL056W PTC3 SGDID:S000000152, Chr II from 113762-115168, Genome Release 64-1-1, Verified ORF, "Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA damage checkpoint inactivation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P34221    468   PP2C3_YEAST Protein phosphatase 2C homolog 3 ...4680     960     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IGI:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:SGD.
2P39966    464   PP2C2_YEAST Protein phosphatase 2C homolog 2 ...4580     556     60     76GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0000077; P:DNA damage checkpoint; IGI:SGD.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:SGD.
3Q09173    414   PP2C3_SCHPO Protein phosphatase 2C homolog 3 ...3101e-95     301     48     69GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:PomBase.
GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:PomBase.::GO:0006470; P:protein dephosphorylation; IDA:PomBase.
4Q09172    370   PP2C2_SCHPO Protein phosphatase 2C homolog 2 ...3117e-92     290     47     64GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:PomBase.
GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:PomBase.::GO:0006470; P:protein dephosphorylation; IDA:PomBase.
5P49596    356   PP2C2_CAEEL Probable protein phosphatase 2C T...2942e-73     242     43     62GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
6Q6ETK3    362   P2C11_ORYSJ Probable protein phosphatase 2C 1...3422e-64     218     39     54GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
7O81716    355   P2C21_ARATH Probable protein phosphatase 2C 2...3484e-62     212     38     54GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IDA:TAIR.
8P49444    300   PP2C1_PARTE Protein phosphatase 2C 1 OS=Param...3094e-62     210     39     55GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
9A0BQL0    300   PP2C3_PARTE Probable protein phosphatase 2C 3...3093e-61     207     40     55GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
10Q653S3    362   P2C70_ORYSJ Probable protein phosphatase 2C 7...3451e-60     208     37     53GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
11A0BLX0    300   PP2C2_PARTE Probable protein phosphatase 2C 2...3094e-60     205     39     55GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
12Q67UP9    368   P2C58_ORYSJ Probable protein phosphatase 2C 5...3422e-59     205     37     54GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
13A0DTY1    301   PP2C4_PARTE Probable protein phosphatase 2C 4...3079e-59     201     39     55GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
14Q9SZ53    357   P2C60_ARATH Probable protein phosphatase 2C 6...3493e-58     201     36     51GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
15A0DSB3    295   PP2C6_PARTE Probable protein phosphatase 2C 6...3043e-52     184     36     54GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
16A0CUB5    295   PP2C5_PARTE Probable protein phosphatase 2C 5...3029e-52     182     36     54GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
17Q7XU84    352   P2C42_ORYSJ Probable protein phosphatase 2C 4...3316e-51     182     35     53GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
18P38089    393   PP2C4_YEAST Protein phosphatase 2C homolog 4 ...3896e-45     167     30     47GO:0005737; C:cytoplasm; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0006470; P:protein dephosphorylation; IDA:SGD.
19P35815    390   PPM1B_RAT Protein phosphatase 1B OS=Rattus no...3077e-45     166     36     52GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
20O62830    484   PPM1B_BOVIN Protein phosphatase 1B OS=Bos tau...3082e-44     167     35     52GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
21P35813    382   PPM1A_HUMAN Protein phosphatase 1A OS=Homo sa...3062e-44     165     35     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0033192; F:calmodulin-dependent protein phosphatase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0010991; P:negative regulation of SMAD protein complex assembly; IDA:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IDA:BHF-UCL.
22P20650    382   PPM1A_RAT Protein phosphatase 1A OS=Rattus no...3062e-44     165     35     53GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.
23P35814    382   PPM1A_RABIT Protein phosphatase 1A OS=Oryctol...3042e-44     165     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase.
24O75688    479   PPM1B_HUMAN Protein phosphatase 1B OS=Homo sa...3082e-44     167     35     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.
25O62829    382   PPM1A_BOVIN Protein phosphatase 1A OS=Bos tau...3062e-44     165     35     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase.
26P36993    390   PPM1B_MOUSE Protein phosphatase 1B OS=Mus mus...3073e-44     164     34     51GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
27P49443    382   PPM1A_MOUSE Protein phosphatase 1A OS=Mus mus...3065e-44     164     34     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.
GO:0006470; P:protein dephosphorylation; IDA:MGI.
28A3A8W2    340   P2C21_ORYSJ Probable protein phosphatase 2C 2...3111e-40     153     31     48GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
29Q4R4V2    547   PPM1G_MACFA Protein phosphatase 1G OS=Macaca ...1181e-17     89.4     40     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
30O15355    546   PPM1G_HUMAN Protein phosphatase 1G OS=Homo sa...1181e-17     89     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.
31Q61074    542   PPM1G_MOUSE Protein phosphatase 1G OS=Mus mus...1181e-17     89     41     56GO:0005634; C:nucleus; IDA:MGI.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0007050; P:cell cycle arrest; IDA:MGI.::GO:0006470; P:protein dephosphorylation; IDA:MGI.
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