rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P38207 | 520 | APN2_YEAST DNA-(apurinic or apyrimidinic site... | 520 | 0 | 1077 | 100 | 100 | GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:SGD.::GO:0008311; F:double-stranded DNA specific 3'-5' exodeoxyribonuclease activity; IDA:SGD.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0008081; F:phosphoric diester hydrolase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006284; P:base-excision repair; IGI:SGD. | 2 | P87175 | 523 | APN2_SCHPO DNA-(apurinic or apyrimidinic site... | 567 | 3e-52 | 191 | 32 | 48 | GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0008311; F:double-stranded DNA specific 3'-5' exodeoxyribonuclease activity; IMP:PomBase.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0004528; F:phosphodiesterase I activity; ISS:PomBase. | | | | | | | | | | GO:0006284; P:base-excision repair; IC:PomBase.::GO:0034614; P:cellular response to reactive oxygen species; IMP:PomBase. | 3 | Q5E9N9 | 514 | APEX2_BOVIN DNA-(apurinic or apyrimidinic sit... | 563 | 2e-42 | 162 | 25 | 43 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 4 | Q9UBZ4 | 518 | APEX2_HUMAN DNA-(apurinic or apyrimidinic sit... | 568 | 8e-41 | 158 | 25 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 5 | Q68G58 | 516 | APEX2_MOUSE DNA-(apurinic or apyrimidinic sit... | 567 | 2e-39 | 154 | 26 | 43 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 6 | P45951 | 536 | ARP_ARATH Apurinic endonuclease-redox protein... | 345 | 0.000000000000009 | 80.5 | 26 | 41 | GO:0042644; C:chloroplast nucleoid; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:TAIR.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:TAIR. | 7 | P37454 | 252 | EXOA_BACSU Exodeoxyribonuclease OS=Bacillus s... | 346 | 0.00000000009 | 65.9 | 25 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0008853; F:exodeoxyribonuclease III activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:InterPro. | 8 | A1YES6 | 318 | APEX1_GORGO DNA-(apurinic or apyrimidinic sit... | 352 | 0.0000000002 | 65.9 | 25 | 38 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; ISS:UniProtKB. | | | | | | | | | | GO:0080111; P:DNA demethylation; ISS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | P28352 | 317 | APEX1_MOUSE DNA-(apurinic or apyrimidinic sit... | 356 | 0.0000000002 | 65.5 | 24 | 39 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; ISS:UniProtKB.::GO:0016491; F:oxidoreductase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IDA:MGI.::GO:0080111; P:DNA demethylation; ISS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | P43138 | 317 | APEX1_RAT DNA-(apurinic or apyrimidinic site)... | 356 | 0.0000000003 | 65.1 | 24 | 40 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IDA:RGD. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004521; F:endoribonuclease activity; IDA:RGD.::GO:0046872; F:metal ion binding; ISS:UniProtKB.::GO:0051059; F:NF-kappaB binding; IDA:RGD.::GO:0016491; F:oxidoreductase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB. | | | | | | | | | | GO:0007568; P:aging; IDA:RGD.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:RGD.::GO:0071417; P:cellular response to organic nitrogen; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IEP:RGD.::GO:0080111; P:DNA demethylation; ISS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0045750; P:positive regulation of S phase of mitotic cell cycle; IMP:RGD.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042493; P:response to drug; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | A2T7I6 | 318 | APEX1_PONPY DNA-(apurinic or apyrimidinic sit... | 352 | 0.0000000006 | 64.3 | 25 | 38 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; ISS:UniProtKB. | | | | | | | | | | GO:0080111; P:DNA demethylation; ISS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | P27695 | 318 | APEX1_HUMAN DNA-(apurinic or apyrimidinic sit... | 352 | 0.0000000008 | 63.9 | 25 | 38 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005783; C:endoplasmic reticulum; TAS:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005840; C:ribosome; TAS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.::GO:0031490; F:chromatin DNA binding; IDA:UniProtKB.::GO:0003684; F:damaged DNA binding; IDA:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IDA:UniProtKB.::GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.::GO:0004528; F:phosphodiesterase I activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004523; F:ribonuclease H activity; TAS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0004844; F:uracil DNA N-glycosylase activity; TAS:ProtInc. | | | | | | | | | | GO:0006284; P:base-excision repair; TAS:Reactome.::GO:0080111; P:DNA demethylation; IDA:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0043488; P:regulation of mRNA stability; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | A2T6Y4 | 318 | APEX1_PANTR DNA-(apurinic or apyrimidinic sit... | 352 | 0.000000002 | 62.4 | 24 | 38 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; ISS:UniProtKB. | | | | | | | | | | GO:0080111; P:DNA demethylation; ISS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | A1YFZ3 | 318 | APEX1_PANPA DNA-(apurinic or apyrimidinic sit... | 352 | 0.000000002 | 62.4 | 24 | 38 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; ISS:UniProtKB. | | | | | | | | | | GO:0080111; P:DNA demethylation; ISS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | P23196 | 318 | APEX1_BOVIN DNA-(apurinic or apyrimidinic sit... | 363 | 0.000000003 | 62.4 | 25 | 37 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:AgBase. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; ISS:AgBase.::GO:0016491; F:oxidoreductase activity; ISS:UniProtKB.::GO:0008081; F:phosphoric diester hydrolase activity; ISS:AgBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:AgBase. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; ISS:AgBase.::GO:0080111; P:DNA demethylation; ISS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | P27864 | 679 | RRP1_DROME Recombination repair protein 1 OS=... | 355 | 0.00000001 | 61.2 | 23 | 37 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; IDA:FlyBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:FlyBase.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 17 | P51173 | 361 | APEA_DICDI DNA-(apurinic or apyrimidinic site... | 352 | 0.00004 | 49.7 | 22 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0016889; F:endodeoxyribonuclease activity, producing 3'-phosphomonoesters; TAS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006284; P:base-excision repair; TAS:dictyBase. | 18 | A0MTA1 | 310 | APEX1_DANRE DNA-(apurinic or apyrimidinic sit... | 357 | 0.00009 | 48.1 | 22 | 36 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0080111; P:DNA demethylation; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0060047; P:heart contraction; IMP:ZFIN.::GO:0001947; P:heart looping; IMP:ZFIN.::GO:0043066; P:negative regulation of apoptotic process; IMP:ZFIN. | 19 | P44318 | 267 | EX3_HAEIN Exodeoxyribonuclease III OS=Haemoph... | 274 | 0.04 | 39.7 | 22 | 39 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0008853; F:exodeoxyribonuclease III activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 20 | Q8K203 | 606 | NEIL3_MOUSE Endonuclease 8-like 3 OS=Mus musc... | 49 | 2.2 | 34.7 | 37 | 51 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0019104; F:DNA N-glycosylase activity; IDA:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.::GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006284; P:base-excision repair; IDA:UniProtKB.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro. | 21 | Q8TAT5 | 605 | NEIL3_HUMAN Endonuclease 8-like 3 OS=Homo sap... | 48 | 0.13 | 38.5 | 38 | 50 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0000405; F:bubble DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0019104; F:DNA N-glycosylase activity; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.::GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.::GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro. | 22 | O70157 | 1003 | TOP3A_MOUSE DNA topoisomerase 3-alpha OS=Mus ... | 51 | 0.18 | 38.5 | 41 | 53 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 23 | Q3MHN7 | 606 | NEIL3_BOVIN Endonuclease 8-like 3 OS=Bos taur... | 51 | 0.37 | 37.4 | 35 | 49 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0000405; F:bubble DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0019104; F:DNA N-glycosylase activity; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; ISS:UniProtKB.::GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.::GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro. | 24 | Q9ZS96 | 160 | Y4478_ARATH Uncharacterized protein At4g04775... | 50 | 0.98 | 34.7 | 38 | 48 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 25 | Q502M8 | 555 | ERI2_DANRE ERI1 exoribonuclease 2 OS=Danio re... | 47 | 2.1 | 34.7 | 40 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 26 | Q13472 | 1001 | TOP3A_HUMAN DNA topoisomerase 3-alpha OS=Homo... | 57 | 2.6 | 34.7 | 37 | 46 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0007126; P:meiosis; TAS:ProtInc. | 27 | Q8EUH7 | 621 | DNAK_MYCPE Chaperone protein DnaK OS=Mycoplas... | 120 | 5.9 | 33.5 | 27 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. |