rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | B6JY29 | 1456 | VPS10_SCHJY Vacuolar protein sorting/targetin... | 1487 | 5e-151 | 506 | 29 | 46 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 62 | C9SM62 | 1447 | VPS10_VERA1 Vacuolar protein sorting/targetin... | 548 | 0.0000002 | 60.1 | 22 | 40 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 63 | O42930 | 1466 | VPS10_SCHPO Vacuolar protein sorting/targetin... | 1485 | 2e-149 | 501 | 29 | 47 | GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005048; F:signal sequence binding; ISS:PomBase. | | | | | | | | | | GO:0006623; P:protein targeting to vacuole; IMP:PomBase. | 64 | P53752 | 436 | YN95_YEAST Uncharacterized membrane glycoprot... | 432 | 0.00004 | 51.6 | 21 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:SGD. | | | | | | | | | | | | | | | | | | | | | 65 | P25606 | 316 | YCZ0_YEAST Uncharacterized protein YCR100C OS... | 290 | 0.00000000009 | 68.6 | 25 | 40 | | | | | | | | | | | | | | | | | | | | | | 66 | P25657 | 155 | YCY9_YEAST Uncharacterized protein YCR099C OS... | 151 | 5e-58 | 203 | 60 | 79 | | | | | | | | | | | | | | | | | | | | | | 67 | Q98930 | 1592 | SORL_CHICK Sortilin-related receptor OS=Gallu... | 419 | 0.00000000004 | 72 | 23 | 42 | GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0034362; C:low-density lipoprotein particle; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 68 | Q96PQ0 | 1159 | SORC2_HUMAN VPS10 domain-containing receptor ... | 286 | 0.0000000005 | 68.6 | 23 | 46 | | | | | | | | | | | | | | | | | | | | | | 69 | O88307 | 2215 | SORL_MOUSE Sortilin-related receptor OS=Mus m... | 618 | 0.000000000001 | 77 | 23 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0034362; C:low-density lipoprotein particle; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 70 | Q99523 | 831 | SORT_HUMAN Sortilin OS=Homo sapiens (Human). ... | 315 | 0.000000000008 | 73.9 | 25 | 44 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005905; C:coated pit; IDA:BHF-UCL.::GO:0005769; C:early endosome; IDA:BHF-UCL.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:BHF-UCL.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0048406; F:nerve growth factor binding; IPI:BHF-UCL.::GO:0010465; F:nerve growth factor receptor activity; IDA:BHF-UCL.::GO:0030379; F:neurotensin receptor activity, non-G-protein coupled; IDA:BHF-UCL. | | | | | | | | | | GO:0006897; P:endocytosis; IDA:BHF-UCL.::GO:0008333; P:endosome to lysosome transport; IDA:BHF-UCL.::GO:0032509; P:endosome transport via multivesicular body sorting pathway; IDA:BHF-UCL.::GO:0046323; P:glucose import; IMP:BHF-UCL.::GO:0006895; P:Golgi to endosome transport; IDA:BHF-UCL.::GO:0008624; P:induction of apoptosis by extracellular signals; IMP:BHF-UCL.::GO:0014902; P:myotube differentiation; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IDA:BHF-UCL.::GO:0051005; P:negative regulation of lipoprotein lipase activity; IDA:BHF-UCL.::GO:0007218; P:neuropeptide signaling pathway; IDA:BHF-UCL.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0048227; P:plasma membrane to endosome transport; IDA:BHF-UCL.::GO:0010468; P:regulation of gene expression; IMP:BHF-UCL.::GO:0032868; P:response to insulin stimulus; IMP:BHF-UCL.::GO:0016050; P:vesicle organization; IDA:BHF-UCL. | 71 | O54861 | 825 | SORT_RAT Sortilin OS=Rattus norvegicus (Rat).... | 319 | 0.00000000003 | 72.4 | 25 | 43 | GO:0030425; C:dendrite; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:RGD.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0016492; F:G-protein coupled neurotensin receptor activity; TAS:RGD. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; NAS:RGD.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW. | 72 | Q6PHU5 | 825 | SORT_MOUSE Sortilin OS=Mus musculus (Mouse). ... | 319 | 0.00000000009 | 70.5 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046323; P:glucose import; IMP:BHF-UCL.::GO:0014902; P:myotube differentiation; IMP:BHF-UCL.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0032868; P:response to insulin stimulus; IMP:BHF-UCL.::GO:0016050; P:vesicle organization; IMP:BHF-UCL. | 73 | Q95209 | 2213 | SORL_RABIT Sortilin-related receptor OS=Oryct... | 418 | 0.0000000000007 | 78.2 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0034362; C:low-density lipoprotein particle; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 74 | Q92673 | 2214 | SORL_HUMAN Sortilin-related receptor OS=Homo ... | 585 | 0.000000000003 | 75.9 | 23 | 39 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0034362; C:low-density lipoprotein particle; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030169; F:low-density lipoprotein particle binding; IPI:BHF-UCL.::GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc. | 75 | Q9EPR5 | 1159 | SORC2_MOUSE VPS10 domain-containing receptor ... | 274 | 0.000000001 | 67.4 | 23 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 76 | Q8WY21 | 1168 | SORC1_HUMAN VPS10 domain-containing receptor ... | 344 | 3e-16 | 88.6 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008188; F:neuropeptide receptor activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 77 | Q9JLC4 | 1167 | SORC1_MOUSE VPS10 domain-containing receptor ... | 344 | 2e-16 | 89.4 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 78 | Q6NUT7 | 814 | SORT1_DANRE Sortilin OS=Danio rerio (Zebrafis... | 268 | 0.0000000004 | 68.6 | 24 | 42 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006810; P:transport; IEA:UniProtKB-KW. | 79 | P25607 | 182 | YCZ1_YEAST Uncharacterized protein YCR101C OS... | 144 | 2e-33 | 134 | 47 | 64 | GO:0005624; C:membrane fraction; IDA:SGD. | | | | | | | | | | | | | | | | | | | | | 80 | Q9UPU3 | 1222 | SORC3_HUMAN VPS10 domain-containing receptor ... | 344 | 0.00000000000003 | 82 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008188; F:neuropeptide receptor activity; NAS:UniProtKB. | | | | | | | | | | | 81 | Q8VI51 | 1219 | SORC3_MOUSE VPS10 domain-containing receptor ... | 344 | 8e-17 | 90.9 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | |