rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | A0PJP4 | 394 | RIPL1_XENTR RILP-like protein 1 OS=Xenopus tr... | 72 | 2.5 | 35.8 | 33 | 57 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0043526; P:neuroprotection; ISS:UniProtKB. | 392 | Q6BNL1 | 1449 | PAN1_DEBHA Actin cytoskeleton-regulatory comp... | 128 | 6.2 | 35 | 38 | 44 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 393 | Q5FVW6 | 328 | SKAP2_XENTR Src kinase-associated phosphoprot... | 55 | 2.6 | 35.4 | 35 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 394 | Q4JIM5 | 1182 | ABL2_MOUSE Abelson tyrosine-protein kinase 2 ... | 62 | 2.6 | 36.2 | 29 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB. | 395 | Q5XGP7 | 330 | SKA2A_XENLA Src kinase-associated phosphoprot... | 60 | 2.6 | 35.4 | 35 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 396 | Q07840 | 426 | EM13_ECHMU Antigen EM13 OS=Echinococcus multi... | 48 | 2.7 | 35.8 | 35 | 52 | | | | | | | | | | | | | | | | | | | | | | 397 | P42684 | 1182 | ABL2_HUMAN Abelson tyrosine-protein kinase 2 ... | 62 | 2.7 | 36.2 | 29 | 55 | GO:0015629; C:actin cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0051015; F:actin filament binding; TAS:UniProtKB.::GO:0003785; F:actin monomer binding; TAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 398 | Q15700 | 870 | DLG2_HUMAN Disks large homolog 2 OS=Homo sapi... | 41 | 2.7 | 35.8 | 37 | 71 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:ProtInc.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004385; F:guanylate kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 399 | P80192 | 1104 | M3K9_HUMAN Mitogen-activated protein kinase k... | 55 | 2.8 | 35.8 | 35 | 60 | | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0004708; F:MAP kinase kinase activity; NAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 400 | Q6GNV5 | 610 | FNBP1_XENLA Formin-binding protein 1 homolog ... | 62 | 2.8 | 35.8 | 26 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 401 | Q99963 | 347 | SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu... | 55 | 2.8 | 35.4 | 35 | 49 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 402 | Q07839 | 416 | EG13_ECHGR Antigen EG13 OS=Echinococcus granu... | 48 | 2.8 | 35.8 | 35 | 52 | | | | | | | | | | | | | | | | | | | | | | 403 | Q64434 | 451 | PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus m... | 53 | 2.9 | 35.8 | 34 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0060575; P:intestinal epithelial cell differentiation; IMP:UniProtKB.::GO:0045926; P:negative regulation of growth; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; ISS:UniProtKB. | 404 | P31693 | 523 | SRC_RSVPA Tyrosine-protein kinase transformin... | 45 | 3 | 35.8 | 27 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 405 | Q9XYM0 | 271 | CRK_DROME Adapter molecule Crk OS=Drosophila ... | 65 | 3 | 35 | 29 | 54 | | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; IDA:FlyBase. | | | | | | | | | | GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007520; P:myoblast fusion; TAS:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IDA:FlyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 406 | Q8I1A6 | 366 | SH3G3_DROWI Endophilin-A OS=Drosophila willis... | 59 | 3.1 | 35.4 | 31 | 56 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 407 | O55043 | 646 | ARHG7_RAT Rho guanine nucleotide exchange fac... | 74 | 3.2 | 35.8 | 24 | 54 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0043615; P:astrocyte cell migration; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD. | 408 | Q9TU19 | 565 | NPHP1_CANFA Nephrocystin-1 OS=Canis familiari... | 59 | 8.6 | 34.3 | 32 | 53 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030030; P:cell projection organization; IEA:UniProtKB-KW. | 409 | Q9JJS5 | 961 | SH3B4_RAT SH3 domain-binding protein 4 OS=Rat... | 64 | 3.3 | 35.8 | 36 | 47 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 410 | Q8I1C0 | 369 | SH3G3_DROPS Endophilin-A OS=Drosophila pseudo... | 34 | 3.3 | 35.4 | 38 | 74 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 411 | Q9UFD9 | 1639 | RIM3A_HUMAN RIMS-binding protein 3A OS=Homo s... | 45 | 3.3 | 35.8 | 38 | 60 | | | | | | | | | | | | | | | | | | | | | | 412 | Q8I190 | 369 | SH3G3_DROVI Endophilin-A OS=Drosophila virili... | 34 | 3.3 | 35.4 | 38 | 74 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 413 | Q921I6 | 962 | SH3B4_MOUSE SH3 domain-binding protein 4 OS=M... | 64 | 3.4 | 35.8 | 36 | 47 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 414 | Q1KKW7 | 363 | SKAP1_TAKRU Src kinase-associated phosphoprot... | 52 | 3.5 | 35.4 | 35 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 415 | Q58DL7 | 561 | ARHG9_BOVIN Rho guanine nucleotide exchange f... | 112 | 3.7 | 35.4 | 31 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 416 | Q80VA5 | 1289 | S3TC2_MOUSE SH3 domain and tetratricopeptide ... | 63 | 3.7 | 35.4 | 32 | 52 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 417 | Q1KKZ1 | 329 | SKAP2_TAKRU Src kinase-associated phosphoprot... | 50 | 3.8 | 35 | 34 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 418 | O08641 | 340 | SH3Y1_MOUSE SH3 domain-containing YSC84-like ... | 57 | 3.8 | 35 | 32 | 53 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 419 | A7EK16 | 1230 | MYO1_SCLS1 Myosin-1 OS=mold) (Whetzelinia scl... | 61 | 4 | 35.4 | 30 | 56 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 420 | O94406 | 343 | PRP18_SCHPO Pre-mRNA-splicing factor 18 OS=Sc... | 83 | 4 | 35 | 35 | 55 | GO:0005681; C:spliceosomal complex; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase. | 421 | Q0IHE5 | 394 | RIPL1_XENLA RILP-like protein 1 OS=Xenopus la... | 79 | 4 | 35 | 33 | 56 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0043526; P:neuroprotection; ISS:UniProtKB. |