Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBL007C
Length:
1244
Number of sequences:
5887
Description:
YBL007C SLA1 SGDID:S000000103, Chr II from 216366-212632, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361D9IVE5    432   ANM2_XENLA Protein arginine N-methyltransfera...561.4     36.6     34     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; IDA:UniProtKB.
GO:0048588; P:developmental cell growth; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.
362P0CR78    660   HSE1_CRYNJ Class E vacuolar protein-sorting m...661.5     37     30     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
363Q1LUA6    3028   TRIO_DANRE Triple functional domain protein O...551.5     37     36     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
364Q6XZF7    1577   DNMBP_HUMAN Dynamin-binding protein OS=Homo s...628.2     34.7     32     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
365Q9P864    296   SHO1_CYBJA High osmolarity signaling protein ...641.5     36.2     31     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
366P70248    1099   MYO1F_MOUSE Unconventional myosin-If OS=Mus m...561.6     37     32     55GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
367Q6NU51    957   SH34B_XENLA SH3 domain-binding protein 4-B OS...611.6     36.6     36     49GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
368O00160    1098   MYO1F_HUMAN Unconventional myosin-If OS=Homo ...561.6     36.6     34     55GO:0016461; C:unconventional myosin complex; NAS:UniProtKB.
GO:0003779; F:actin binding; NAS:UniProtKB.::GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.
369A5D8S5    867   SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF...591.6     36.6     31     56GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
370A5DP36    1440   PAN1_PICGU Actin cytoskeleton-regulatory comp...1861.7     36.6     34     40GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
371Q5EBL4    403   RIPL1_HUMAN RILP-like protein 1 OS=Homo sapie...711.7     36.2     35     58GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
372Q8AXV0    367   SH3G1_CHICK Endophilin-A2 OS=Gallus gallus (C...551.8     36.2     35     55GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
373Q6C2N2    685   HSE1_YARLI Class E vacuolar protein-sorting m...661.9     36.6     27     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
374Q3V0F0    1490   RIMB3_MOUSE RIMS-binding protein 3 OS=Mus mus...722     36.6     31     51GO:0005634; C:nucleus; IDA:MGI.
375Q9C9A9    392   COL7_ARATH Zinc finger protein CONSTANS-LIKE ...642     36.2     36     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.
376Q9ES28    862   ARHG7_MOUSE Rho guanine nucleotide exchange f...912     36.6     23     53GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
377A6NJZ7    1639   RIM3C_HUMAN RIMS-binding protein 3C OS=Homo s...452.1     36.6     38     60
378A6NNM3    1639   RIM3B_HUMAN RIMS-binding protein 3B OS=Homo s...452.1     36.6     38     60
379Q04439    1219   MYO5_YEAST Myosin-5 OS=Saccharomyces cerevisi...522.1     36.6     38     58GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; TAS:SGD.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0006887; P:exocytosis; TAS:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD.::GO:0006898; P:receptor-mediated endocytosis; IMP:SGD.::GO:0009651; P:response to salt stress; IPI:SGD.
380A6ZMG6    1219   MYO5_YEAS7 Myosin-5 OS=Saccharomyces cerevisi...522.1     36.6     38     58GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
381O15259    732   NPHP1_HUMAN Nephrocystin-1 OS=Homo sapiens (H...512.1     36.2     37     61GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0031514; C:motile cilium; IDA:UniProtKB.::GO:0032391; C:photoreceptor connecting cilium; ISS:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005198; F:structural molecule activity; NAS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0030030; P:cell projection organization; ISS:UniProtKB.::GO:0016337; P:cell-cell adhesion; NAS:UniProtKB.::GO:0007588; P:excretion; TAS:ProtInc.::GO:0060041; P:retina development in camera-type eye; ISS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.::GO:0048515; P:spermatid differentiation; ISS:UniProtKB.::GO:0007632; P:visual behavior; NAS:UniProtKB.
382P09851    1044   RASA1_BOVIN Ras GTPase-activating protein 1 O...572.2     36.2     33     61GO:0005737; C:cytoplasm; ISS:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; ISS:RefGenome.
GO:0051020; F:GTPase binding; ISS:AgBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; ISS:RefGenome.::GO:0005102; F:receptor binding; ISS:AgBase.
GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0001953; P:negative regulation of cell-matrix adhesion; ISS:AgBase.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:RefGenome.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:AgBase.::GO:0030833; P:regulation of actin filament polymerization; ISS:AgBase.::GO:0007165; P:signal transduction; ISS:AgBase.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.
383Q96RU3    617   FNBP1_HUMAN Formin-binding protein 1 OS=Homo ...622.3     36.2     26     58GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
384Q3U1V8    1077   M3K9_MOUSE Mitogen-activated protein kinase k...552.3     36.2     35     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
385P47941    303   CRKL_MOUSE Crk-like protein OS=Mus musculus (...582.4     35.8     31     53
GO:0005515; F:protein binding; IPI:MGI.
GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI.
386Q6NU22    957   SH34A_XENLA SH3 domain-binding protein 4-A OS...612.4     36.2     36     49GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
387Q5U2U2    303   CRKL_RAT Crk-like protein OS=Rattus norvegicu...582.5     35.4     31     53
388P50904    1038   RASA1_RAT Ras GTPase-activating protein 1 OS=...572.5     36.2     33     61GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0007155; P:cell adhesion; NAS:UniProtKB.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0001953; P:negative regulation of cell-matrix adhesion; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.::GO:0007165; P:signal transduction; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.
389P46109    303   CRKL_HUMAN Crk-like protein OS=Homo sapiens (...582.5     35.4     31     53GO:0005829; C:cytosol; TAS:Reactome.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
390P20936    1047   RASA1_HUMAN Ras GTPase-activating protein 1 O...572.5     36.2     33     61GO:0005829; C:cytosol; TAS:Reactome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0001948; F:glycoprotein binding; IPI:UniProtKB.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019870; F:potassium channel inhibitor activity; NAS:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.::GO:0005102; F:receptor binding; IPI:UniProtKB.
GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; NAS:UniProtKB.::GO:0051252; P:regulation of RNA metabolic process; NAS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.
391A0PJP4    394   RIPL1_XENTR RILP-like protein 1 OS=Xenopus tr...722.5     35.8     33     57GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
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