rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | A8XI74 | 277 | CED2_CAEBR Cell death abnormality protein 2 O... | 92 | 0.94 | 37 | 28 | 47 | | | | | | | | | | | GO:0032403; F:protein complex binding; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0043652; P:engulfment of apoptotic cell; ISS:UniProtKB.::GO:0007165; P:signal transduction; ISS:UniProtKB. | 332 | E9EM69 | 306 | SHO1_METAR High osmolarity signaling protein ... | 55 | 0.95 | 37 | 31 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 333 | B0CRJ3 | 1252 | MYO1_LACBS Myosin-1 OS=deceiver) (Laccaria la... | 60 | 0.95 | 37.4 | 37 | 62 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 334 | Q54CL3 | 570 | PEX13_DICDI Probable peroxisomal membrane pro... | 86 | 1 | 37.4 | 26 | 50 | GO:0005779; C:integral to peroxisomal membrane; ISS:dictyBase. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; ISS:dictyBase. | 335 | Q9Y5K6 | 639 | CD2AP_HUMAN CD2-associated protein OS=Homo sa... | 62 | 1 | 37.4 | 32 | 58 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006461; P:protein complex assembly; TAS:ProtInc.::GO:0007165; P:signal transduction; NAS:ProtInc.::GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc. | 336 | Q09165 | 13100 | DIG1_CAEEL Mesocentin OS=Caenorhabditis elega... | 264 | 1.1 | 37.4 | 23 | 37 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0007413; P:axonal fasciculation; IMP:WormBase.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 337 | Q9CX99 | 217 | GRAP_MOUSE GRB2-related adapter protein OS=Mu... | 53 | 2.5 | 35 | 28 | 58 | | | | | | | | | | | | | | | | | | | | | | 338 | Q17QG3 | 403 | RIPL1_BOVIN RILP-like protein 1 OS=Bos taurus... | 71 | 1.1 | 37 | 35 | 58 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0043526; P:neuroprotection; ISS:UniProtKB. | 339 | Q68F99 | 337 | STAC3_XENTR SH3 and cysteine-rich domain-cont... | 56 | 1.1 | 37 | 32 | 63 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 340 | Q75DS3 | 443 | HSE1_ASHGO Class E vacuolar protein-sorting m... | 49 | 1.1 | 37 | 35 | 55 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 341 | Q555L8 | 389 | Y4695_DICDI SH3 and FCH domain-containing pro... | 71 | 1.2 | 37 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | | 342 | Q91XM9 | 852 | DLG2_MOUSE Disks large homolog 2 OS=Mus muscu... | 41 | 1.2 | 37 | 37 | 71 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0019233; P:sensory perception of pain; IMP:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI. | 343 | P39969 | 1040 | BOI2_YEAST Protein BOI2 OS=Saccharomyces cere... | 57 | 1.2 | 37 | 30 | 58 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007118; P:budding cell apical bud growth; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD. | 344 | Q63622 | 852 | DLG2_RAT Disks large homolog 2 OS=Rattus norv... | 41 | 1.2 | 37 | 37 | 71 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; TAS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0045161; P:neuronal ion channel clustering; IMP:RGD.::GO:0043113; P:receptor clustering; IMP:RGD. | 345 | Q96AG4 | 307 | LRC59_HUMAN Leucine-rich repeat-containing pr... | 48 | 1.3 | 36.6 | 42 | 63 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0042645; C:mitochondrial nucleoid; IDA:BHF-UCL. | | | | | | | | | | | | | | | | | | | | | 346 | Q8QFX1 | 1325 | RIMB2_CHICK RIMS-binding protein 2 OS=Gallus ... | 58 | 1.3 | 37 | 36 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 347 | Q8BZ71 | 360 | STAC3_MOUSE SH3 and cysteine-rich domain-cont... | 56 | 1.3 | 36.6 | 32 | 55 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 348 | Q5T0N5 | 605 | FBP1L_HUMAN Formin-binding protein 1-like OS=... | 62 | 1.3 | 37 | 31 | 60 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 349 | Q13588 | 217 | GRAP_HUMAN GRB2-related adapter protein OS=Ho... | 60 | 2.2 | 35.4 | 32 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 350 | P20929 | 6669 | NEBU_HUMAN Nebulin OS=Homo sapiens (Human). G... | 53 | 1.3 | 37.4 | 34 | 62 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc. | | | | | | | | | | GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030832; P:regulation of actin filament length; NAS:UniProtKB.::GO:0007525; P:somatic muscle development; NAS:UniProtKB. | 351 | Q63768 | 304 | CRK_RAT Adapter molecule crk OS=Rattus norveg... | 54 | 1.3 | 36.6 | 35 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:RGD.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0051270; P:regulation of cellular component movement; TAS:RGD.::GO:0035020; P:regulation of Rac protein signal transduction; IMP:RGD.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 352 | Q9US59 | 140 | SKB5_SCHPO Shk1 kinase-binding protein 5 OS=S... | 92 | 4.1 | 33.5 | 26 | 40 | GO:0005783; C:endoplasmic reticulum; IDA:PomBase. | | | | | | | | | | GO:0019901; F:protein kinase binding; IDA:UniProtKB. | | | | | | | | | | | 353 | Q8TC17 | 118 | GRAPL_HUMAN GRB2-related adapter protein-like... | 52 | 1.4 | 34.7 | 31 | 50 | | | | | | | | | | | | | | | | | | | | | | 354 | Q8AXQ3 | 966 | SH3B4_SERQU SH3 domain-binding protein 4 OS=S... | 90 | 1.4 | 37 | 29 | 49 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 355 | Q00647 | 1249 | MYO1_EMENI Myosin-1 OS=194 / M139) (Aspergill... | 50 | 1.4 | 37 | 30 | 56 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 356 | Q64010 | 304 | CRK_MOUSE Adapter molecule crk OS=Mus musculu... | 54 | 1.4 | 36.2 | 35 | 56 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 357 | Q96MF2 | 364 | STAC3_HUMAN SH3 and cysteine-rich domain-cont... | 56 | 1.4 | 36.6 | 32 | 55 | | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 358 | P80667 | 386 | PEX13_YEAST Peroxisomal membrane protein PAS2... | 63 | 1.4 | 36.6 | 32 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IGI:SGD. | 359 | P46108 | 304 | CRK_HUMAN Adapter molecule crk OS=Homo sapien... | 54 | 1.4 | 36.2 | 35 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc. | 360 | Q4P5J4 | 593 | HSE1_USTMA Class E vacuolar protein-sorting m... | 115 | 1.4 | 36.6 | 27 | 44 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 361 | D9IVE5 | 432 | ANM2_XENLA Protein arginine N-methyltransfera... | 56 | 1.4 | 36.6 | 34 | 55 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; IDA:UniProtKB. | | | | | | | | | | GO:0048588; P:developmental cell growth; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB. |