Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBL007C
Length:
1244
Number of sequences:
5887
Description:
YBL007C SLA1 SGDID:S000000103, Chr II from 216366-212632, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q6NRL2    550   SNX33_XENLA Sorting nexin-33 OS=Xenopus laevi...580.53     38.1     31     59
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
302Q8K012    605   FBP1L_MOUSE Formin-binding protein 1-like OS=...620.55     38.1     32     60GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
303Q96KQ4    1090   ASPP1_HUMAN Apoptosis-stimulating of p53 prot...510.56     38.1     33     55GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.
304P16546    2472   SPTA2_MOUSE Spectrin alpha chain, brain OS=Mu...563     35.8     30     57GO:0032437; C:cuticular plate; IDA:MGI.::GO:0005916; C:fascia adherens; IDA:MGI.::GO:0016328; C:lateral plasma membrane; IDA:MGI.::GO:0033270; C:paranode region of axon; IDA:BHF-UCL.::GO:0030018; C:Z disc; IDA:MGI.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IDA:MGI.::GO:0030507; F:spectrin binding; IDA:MGI.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
305Q13813    2472   SPTA2_HUMAN Spectrin alpha chain, brain OS=Ho...562.9     36.2     30     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA.::GO:0008091; C:spectrin; TAS:ProtInc.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.
306P16086    2472   SPTA2_RAT Spectrin alpha chain, brain OS=Ratt...563     35.8     30     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0008091; C:spectrin; TAS:RGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0047485; F:protein N-terminus binding; IPI:RGD.::GO:0019905; F:syntaxin binding; IPI:RGD.
GO:0031532; P:actin cytoskeleton reorganization; IMP:RGD.::GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
307P07751    2477   SPTA2_CHICK Spectrin alpha chain, brain OS=Ga...563     35.8     30     57GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
308Q7Z8J6    1282   MYO1_USTMA Myosin-1 OS=Ustilago maydis (strai...600.58     38.1     32     53GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
309P10447    439   ABL_FSVHY Tyrosine-protein kinase transformin...620.59     37.7     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
310Q4P9Q7    335   SHO1_USTMA High osmolarity signaling protein ...580.6     37.7     34     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
311Q10199    670   IMP2_SCHPO Septation protein imp2 OS=Schizosa...670.63     38.1     31     54GO:0005826; C:actomyosin contractile ring; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
312B3DLB3    433   ANM2_XENTR Protein arginine N-methyltransfera...660.65     37.7     32     58GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:UniProtKB.
GO:0048588; P:developmental cell growth; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.
313Q9URW6    430   YIE2_SCHPO SH3 domain-containing protein PJ69...590.67     37.7     31     61GO:0030479; C:actin cortical patch; ISS:PomBase.
GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.
314Q13625    1128   ASPP2_HUMAN Apoptosis-stimulating of p53 prot...581.8     36.6     31     57GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
315Q2KJB5    505   NOSTN_BOVIN Nostrin OS=Bos taurus (Bovine). G...520.68     37.7     40     52GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
316Q9Y7Z8    1217   MYO1_SCHPO Myosin-1 OS=Schizosaccharomyces po...493.7     35.4     35     57GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0005826; C:actomyosin contractile ring; TAS:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0045121; C:membrane raft; IDA:PomBase.::GO:0045160; C:myosin I complex; TAS:PomBase.::GO:0005628; C:prospore membrane; IDA:PomBase.::GO:0030427; C:site of polarized growth; IDA:PomBase.
GO:0003779; F:actin binding; NAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; TAS:PomBase.
GO:0000147; P:actin cortical patch assembly; IGI:PomBase.::GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0045010; P:actin nucleation; IDA:PomBase.::GO:0030476; P:ascospore wall assembly; IMP:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:PomBase.::GO:0031580; P:membrane raft distribution; IMP:PomBase.::GO:0051127; P:positive regulation of actin nucleation; IMP:PomBase.::GO:0030100; P:regulation of endocytosis; IMP:PomBase.
317Q91ZR2    614   SNX18_MOUSE Sorting nexin-18 OS=Mus musculus ...580.69     37.7     29     60GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
318Q9JIR1    1049   RIMB2_RAT RIMS-binding protein 2 OS=Rattus no...680.69     38.1     35     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:RGD.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
319Q9JLQ0    637   CD2AP_MOUSE CD2-associated protein OS=Mus mus...668.4     34.3     30     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
320Q2KJA1    368   SH3G1_BOVIN Endophilin-A2 OS=Bos taurus (Bovi...550.7     37.4     35     55GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
321Q80U40    1072   RIMB2_MOUSE RIMS-binding protein 2 OS=Mus mus...680.7     38.1     37     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
322O74749    373   HSE1_SCHPO Class E vacuolar protein-sorting m...620.73     37.4     34     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
323O77506    263   LASP1_RABIT LIM and SH3 domain protein 1 OS=O...586.4     34.3     33     50GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
324O15034    1052   RIMB2_HUMAN RIMS-binding protein 2 OS=Homo sa...680.76     37.7     37     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
325Q922Q8    307   LRC59_MOUSE Leucine-rich repeat-containing pr...840.79     37.4     31     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
326P34258    493   YKA7_CAEEL Uncharacterized protein B0303.7 OS...840.86     37.4     32     44
327Q6ZQT0    140   YD023_HUMAN Putative uncharacterized protein ...1190.87     35.4     27     43
328Q96RF0    628   SNX18_HUMAN Sorting nexin-18 OS=Homo sapiens ...580.88     37.4     29     59GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006897; P:endocytosis; IDA:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
329Q08881    620   ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=...580.89     37.4     38     59GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
330Q5E9X4    306   LRC59_BOVIN Leucine-rich repeat-containing pr...830.94     37     35     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
331A8XI74    277   CED2_CAEBR Cell death abnormality protein 2 O...920.94     37     28     47
GO:0032403; F:protein complex binding; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0043652; P:engulfment of apoptotic cell; ISS:UniProtKB.::GO:0007165; P:signal transduction; ISS:UniProtKB.
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