Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YBL007C
Length:
1244
Number of sequences:
5887
Description:
YBL007C SLA1 SGDID:S000000103, Chr II from 216366-212632, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32790    1244   SLA1_YEAST Actin cytoskeleton-regulatory comp...12440     2574     100     100GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0006897; P:endocytosis; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD.
2A6ZKU1    1244   SLA1_YEAS7 Actin cytoskeleton-regulatory comp...12440     2560     99     99GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
3A7TKW4    1202   SLA1_VANPO Actin cytoskeleton-regulatory comp...13120     1152     52     65GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
4A7E8B6    1150   SLA1_SCLS1 Actin cytoskeleton-regulatory comp...9311e-123     417     32     48GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
5Q6CHN0    1136   SLA1_YARLI Actin cytoskeleton-regulatory comp...3566e-23     110     31     45GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
6O13736    1420   SLA1_SCHPO Actin cytoskeleton-regulatory comp...2121e-25     119     36     54GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; ISS:PomBase.
7Q4P3H6    1207   SLA1_USTMA Actin cytoskeleton-regulatory comp...570.034     42.4     37     63GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
8A7TSV7    1492   PAN1_VANPO Actin cytoskeleton-regulatory comp...780.24     39.7     42     53GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
9A6ZVS5    1460   PAN1_YEAS7 Actin cytoskeleton-regulatory comp...2480.0000006     57.8     33     45GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
10P32521    1480   PAN1_YEAST Actin cytoskeleton-regulatory comp...2890.62     38.1     29     39GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.
GO:0000147; P:actin cortical patch assembly; IMP:SGD.::GO:0007120; P:axial cellular bud site selection; IMP:SGD.::GO:0007121; P:bipolar cellular bud site selection; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.
11Q6FPQ7    1374   PAN1_CANGA Actin cytoskeleton-regulatory comp...2160.00001     53.9     35     42GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
12Q5AHB1    1397   PAN1_CANAL Actin cytoskeleton-regulatory comp...2530.000004     55.1     35     42GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030427; C:site of polarized growth; IDA:CGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IMP:CGD.::GO:0009826; P:unidimensional cell growth; IMP:CGD.
13Q8TEJ3    882   SH3R3_HUMAN SH3 domain-containing RING finger...650.25     39.3     29     55
GO:0008270; F:zinc ion binding; IEA:InterPro.
14Q92882    214   OSTF1_HUMAN Osteoclast-stimulating factor 1 O...491.7     35.8     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001503; P:ossification; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
15Q8MJ50    214   OSTF1_BOVIN Osteoclast-stimulating factor 1 O...512.9     35     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
16Q5ZJJ9    202   OSTF1_CHICK Osteoclast-stimulating factor 1 O...512.1     35.4     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
17Q8MJ49    214   OSTF1_PIG Osteoclast-stimulating factor 1 OS=...491.9     35.4     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
18Q7ZYG4    214   OSTF1_XENLA Osteoclast-stimulating factor 1 O...512.7     35     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
19Q9WVE9    1217   ITSN1_RAT Intersectin-1 OS=Rattus norvegicus ...570.48     38.5     33     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; TAS:RGD.
20Q6P686    214   OSTF1_RAT Osteoclast-stimulating factor 1 OS=...515     34.3     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
21P09769    529   FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo...540.007     44.3     37     59GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc.
22Q62422    215   OSTF1_MOUSE Osteoclast-stimulating factor 1 O...515.3     34.3     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IDA:MGI.
23Q9Z0R4    1714   ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo...680.44     38.5     29     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
24O93436    468   STAM2_CHICK Signal transducing adapter molecu...975     35     27     47GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
25Q6TGW5    214   OSTF1_DANRE Osteoclast-stimulating factor 1 O...632.6     35     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
26Q8C120    878   SH3R3_MOUSE SH3 domain-containing RING finger...601.2     37     33     58
GO:0008270; F:zinc ion binding; IEA:InterPro.
27Q6CVA8    508   HSE1_KLULA Class E vacuolar protein-sorting m...600.012     43.5     35     57GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
28O75886    525   STAM2_HUMAN Signal transducing adapter molecu...640.066     41.2     31     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
29Q9P7E8    857   APP1_SCHPO Protein app1 OS=Schizosaccharomyce...1340.00009     50.4     30     46GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.
GO:0003779; F:actin binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IC:PomBase.
30O42287    1270   ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (...1761.9     36.6     23     38GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
31P39688    537   FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus ...644.9     35     30     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0015631; F:tubulin binding; IDA:MGI.
GO:0050798; P:activated T cell proliferation; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0042552; P:myelination; TAS:MGI.::GO:0010629; P:negative regulation of gene expression; IMP:BHF-UCL.::GO:0042177; P:negative regulation of protein catabolic process; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0045471; P:response to ethanol; IGI:MGI.
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