Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YAR042W
Length:
1188
Number of sequences:
5887
Description:
YAR042W SWH1 SGDID:S000000081, Chr I from 192619-196185, Genome Release 64-1-1, Verified ORF, "Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the Golgi and the nucleus-vacuole junction"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q8GXE6    888   AKT6_ARATH Potassium channel AKT6 OS=Arabidop...1360.72     37.7     28     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
182Q9Z2X2    231   PSD10_MOUSE 26S proteasome non-ATPase regulat...1770.73     37     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
183Q9Z1E3    314   IKBA_MOUSE NF-kappa-B inhibitor alpha OS=Mus ...2370.77     37     24     41GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:0045638; P:negative regulation of myeloid cell differentiation; IMP:MGI.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:MGI.::GO:0070427; P:nucleotide-binding oligomerization domain containing 1 signaling pathway; IDA:MGI.::GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IDA:MGI.::GO:0000060; P:protein import into nucleus, translocation; IDA:MGI.::GO:0042127; P:regulation of cell proliferation; IDA:MGI.::GO:0043330; P:response to exogenous dsRNA; IDA:MGI.::GO:0032495; P:response to muramyl dipeptide; IDA:MGI.::GO:0034142; P:toll-like receptor 4 signaling pathway; IDA:MGI.
184Q00IB7    1433   PKHH1_DANRE Pleckstrin homology domain-contai...950.78     37.7     26     49GO:0005856; C:cytoskeleton; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001569; P:patterning of blood vessels; IMP:ZFIN.
185Q9H560    264   ANR19_HUMAN Putative ankyrin repeat domain-co...1300.79     37     25     43
186Q5I155    167   IKBF2_MDBVW I-Kappa-B like protein F2 OS=Micr...320.8     36.2     50     63
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
187Q80YE7    1442   DAPK1_MOUSE Death-associated protein kinase 1...660.84     37.7     33     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IMP:UniProtKB.
188Q3V096    527   ANR42_MOUSE Ankyrin repeat domain-containing ...1614.1     35     23     46GO:0005634; C:nucleus; IDA:MGI.
GO:0051059; F:NF-kappaB binding; IPI:MGI.
GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IMP:MGI.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:MGI.
189Q9TU71    319   ANKR1_RABIT Ankyrin repeat domain-containing ...500.93     37     42     60
190Q9VUX2    1226   MIB_DROME E3 ubiquitin-protein ligase mind-bo...1900.93     37.4     27     44GO:0045179; C:apical cortex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0046331; P:lateral inhibition; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB.::GO:0007423; P:sensory organ development; IMP:FlyBase.
191Q94CT7    446   XB31_ORYSJ Probable E3 ubiquitin-protein liga...1090.96     37     27     40
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
192Q02989    1411   LITA_LATTR Alpha-latroinsectotoxin-Lt1a OS=(L...340.96     37.4     53     68GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0072556; C:other organism presynaptic membrane; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
193Q1RHQ8    225   Y1025_RICBR Putative ankyrin repeat protein R...1410.97     36.6     23     41
194Q54HW1    232   PSD10_DICDI 26S proteasome non-ATPase regulat...2230.99     36.6     23     40
195A5PMU4    1280   ANS1B_DANRE Ankyrin repeat and sterile alpha ...1930.99     37.4     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
196P08567    350   PLEK_HUMAN Pleckstrin OS=Homo sapiens (Human)...1061.1     37     28     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0005624; C:membrane fraction; IDA:BHF-UCL.::GO:0032587; C:ruffle membrane; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; IDA:BHF-UCL.
GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005080; F:protein kinase C binding; IDA:BHF-UCL.
GO:0031532; P:actin cytoskeleton reorganization; IDA:BHF-UCL.::GO:0030866; P:cortical actin cytoskeleton organization; IDA:BHF-UCL.::GO:0002244; P:hemopoietic progenitor cell differentiation; IEP:BHF-UCL.::GO:0030845; P:inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway; IDA:BHF-UCL.::GO:0007229; P:integrin-mediated signaling pathway; IDA:BHF-UCL.::GO:0050849; P:negative regulation of calcium-mediated signaling; NAS:BHF-UCL.::GO:0010920; P:negative regulation of inositol phosphate biosynthetic process; IDA:BHF-UCL.::GO:0046488; P:phosphatidylinositol metabolic process; IDA:BHF-UCL.::GO:0070527; P:platelet aggregation; ISS:BHF-UCL.::GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0030836; P:positive regulation of actin filament depolymerization; IDA:BHF-UCL.::GO:0010925; P:positive regulation of inositol-polyphosphate 5-phosphatase activity; IDA:BHF-UCL.::GO:0033625; P:positive regulation of integrin activation; ISS:BHF-UCL.::GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.::GO:0070528; P:protein kinase C signaling cascade; ISS:BHF-UCL.::GO:0070560; P:protein secretion by platelet; ISS:BHF-UCL.::GO:0060305; P:regulation of cell diameter; IDA:BHF-UCL.::GO:0031529; P:ruffle organization; IDA:BHF-UCL.::GO:0070493; P:thrombin receptor signaling pathway; IDA:BHF-UCL.::GO:0006904; P:vesicle docking involved in exocytosis; ISS:BHF-UCL.
197Q60773    166   CDN2D_MOUSE Cyclin-dependent kinase 4 inhibit...1291.1     35.8     22     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
198Q5W7F2    827   AGD3_ARATH ADP-ribosylation factor GTPase-act...811.2     37     30     44GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IDA:TAIR.::GO:0035091; F:phosphatidylinositol binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0009733; P:response to auxin stimulus; IMP:TAIR.::GO:0010051; P:xylem and phloem pattern formation; IMP:TAIR.
199Q7Z020    1296   TRPA1_DROME Transient receptor potential cati...1031.2     37     29     44GO:0016021; C:integral to membrane; IC:UniProtKB.
GO:0005261; F:cation channel activity; IDA:UniProtKB.
GO:0034605; P:cellular response to heat; IDA:FlyBase.::GO:0042745; P:circadian sleep/wake cycle; IMP:FlyBase.::GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IMP:FlyBase.::GO:0007613; P:memory; IMP:FlyBase.::GO:0043052; P:thermotaxis; IDA:FlyBase.
200P55273    166   CDN2D_HUMAN Cyclin-dependent kinase 4 inhibit...1031.2     35.4     29     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
GO:0006916; P:anti-apoptosis; IMP:BHF-UCL.::GO:0048102; P:autophagic cell death; IMP:BHF-UCL.::GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0000731; P:DNA synthesis involved in DNA repair; IMP:BHF-UCL.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0032526; P:response to retinoic acid; IMP:BHF-UCL.::GO:0009411; P:response to UV; IMP:BHF-UCL.::GO:0033280; P:response to vitamin D; IMP:BHF-UCL.
201Q8KX38    174   NDHJ_SYNP2 NAD(P)H-quinone oxidoreductase sub...361.2     35.8     42     64GO:0042651; C:thylakoid membrane; IEA:UniProtKB-SubCell.
GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.::GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
GO:0006810; P:transport; IEA:UniProtKB-KW.
202Q5EFR1    167   IKBI1_MDBVW I-Kappa-B like protein I1 OS=Micr...271.2     35.4     56     67
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
203P42773    168   CDN2C_HUMAN Cyclin-dependent kinase 4 inhibit...581.3     35.4     34     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.
204B0SZ21    313   RS2_CAUSK 30S ribosomal protein S2 OS=Cauloba...1551.3     36.6     23     41GO:0015935; C:small ribosomal subunit; IEA:InterPro.
GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
205O75832    226   PSD10_HUMAN 26S proteasome non-ATPase regulat...1801.4     35.8     24     41GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc.
GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
206A2A2Z9    1011   AN18B_HUMAN Ankyrin repeat domain-containing ...1511.5     36.6     30     41
207P83757    489   CACT_DROYA NF-kappa-B inhibitor cactus OS=Dro...1142.8     35.8     25     39GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0046843; P:dorsal appendage formation; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
208Q9J5H5    436   V026_FOWPN Putative ankyrin repeat protein FP...1751.6     36.6     24     41
209Q5B4E7    372   PPID_EMENI Peptidyl-prolyl cis-trans isomeras...671.6     36.2     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
210Q60772    168   CDN2C_MOUSE Cyclin-dependent kinase 4 inhibit...581.6     35     33     45
GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.
211Q4WIF3    377   PPID_ASPFU Peptidyl-prolyl cis-trans isomeras...661.7     36.2     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
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