rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | P51957 | 841 | NEK4_HUMAN Serine/threonine-protein kinase Ne... | 257 | 2e-27 | 124 | 31 | 51 | GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 422 | Q96GD4 | 344 | AURKB_HUMAN Aurora kinase B OS=Homo sapiens (... | 257 | 2e-27 | 119 | 30 | 52 | GO:0032133; C:chromosome passenger complex; IPI:UniProtKB.::GO:0000780; C:condensed nuclear chromosome, centromeric region; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; TAS:UniProtKB.::GO:0005819; C:spindle; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0008608; P:attachment of spindle microtubules to kinetochore; TAS:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0016570; P:histone modification; TAS:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0002903; P:negative regulation of B cell apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; IMP:UniProtKB.::GO:0051983; P:regulation of chromosome segregation; TAS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; IMP:UniProtKB. | 423 | Q8CEQ0 | 352 | CDKL1_MOUSE Cyclin-dependent kinase-like 1 OS... | 285 | 2e-27 | 119 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 424 | Q5Q0U5 | 431 | SGK1_FUNHE Serine/threonine-protein kinase Sg... | 260 | 2e-27 | 120 | 31 | 49 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 425 | O60285 | 661 | NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS... | 256 | 2e-27 | 122 | 28 | 52 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:2000772; P:regulation of cellular senescence; IDA:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW. | 426 | Q8RX66 | 568 | NEK3_ARATH Serine/threonine-protein kinase Ne... | 306 | 2e-27 | 122 | 25 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 427 | Q96L34 | 752 | MARK4_HUMAN MAP/microtubule affinity-regulati... | 277 | 2e-27 | 123 | 32 | 51 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.::GO:0043130; F:ubiquitin binding; NAS:UniProtKB. | | | | | | | | | | GO:0001578; P:microtubule bundle formation; IEP:UniProtKB.::GO:0007399; P:nervous system development; IDA:UniProtKB.::GO:0043068; P:positive regulation of programmed cell death; NAS:UniProtKB. | 428 | P43063 | 317 | CDK1_CANAL Cyclin-dependent kinase 1 OS=Candi... | 202 | 2e-27 | 119 | 35 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:CGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:CGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IGI:CGD. | 429 | Q6FKD4 | 302 | PHO85_CANGA Negative regulator of the PHO sys... | 211 | 2e-27 | 118 | 35 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 430 | O00141 | 431 | SGK1_HUMAN Serine/threonine-protein kinase Sg... | 352 | 2e-27 | 120 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; TAS:UniProtKB.::GO:0017081; F:chloride channel regulator activity; TAS:UniProtKB.::GO:0015459; F:potassium channel regulator activity; TAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0017080; F:sodium channel regulator activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; TAS:UniProtKB.::GO:0032411; P:positive regulation of transporter activity; TAS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0008217; P:regulation of blood pressure; TAS:UniProtKB.::GO:0050790; P:regulation of catalytic activity; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0060453; P:regulation of gastric acid secretion; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0070294; P:renal sodium ion absorption; TAS:UniProtKB.::GO:0006950; P:response to stress; TAS:ProtInc. | 431 | P53681 | 602 | CRK_DAUCA CDPK-related protein kinase OS=Dauc... | 273 | 2e-27 | 122 | 30 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 432 | Q62073 | 579 | M3K7_MOUSE Mitogen-activated protein kinase k... | 255 | 2e-27 | 122 | 30 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004708; F:MAP kinase kinase activity; IDA:MGI.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0060546; P:negative regulation of necroptosis; IMP:UniProtKB.::GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IMP:UniProtKB.::GO:0001841; P:neural tube formation; IMP:MGI.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:MGI. | 433 | A2VDU3 | 579 | M3K7_BOVIN Mitogen-activated protein kinase k... | 255 | 2e-27 | 122 | 30 | 54 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 434 | Q9C9M7 | 348 | CDKD2_ARATH Cyclin-dependent kinase D-2 OS=Ar... | 286 | 2e-27 | 119 | 31 | 49 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:TAIR. | 435 | Q8CIP4 | 752 | MARK4_MOUSE MAP/microtubule affinity-regulati... | 277 | 2e-27 | 122 | 32 | 51 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0043005; C:neuron projection; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007399; P:nervous system development; ISS:UniProtKB. | 436 | Q5QN75 | 355 | M2K1_ORYSJ Mitogen-activated protein kinase k... | 266 | 2e-27 | 119 | 34 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 437 | D2I3C6 | 784 | DCLK2_AILME Serine/threonine-protein kinase D... | 297 | 2e-27 | 123 | 29 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 438 | Q13163 | 448 | MP2K5_HUMAN Dual specificity mitogen-activate... | 267 | 2e-27 | 120 | 30 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.::GO:0071363; P:cellular response to growth factor stimulus; ISS:BHF-UCL.::GO:0071499; P:cellular response to laminar fluid shear stress; TAS:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; ISS:BHF-UCL.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; ISS:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; ISS:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; ISS:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051247; P:positive regulation of protein metabolic process; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL. | 439 | P11837 | 699 | NIMA_EMENI G2-specific protein kinase nimA OS... | 281 | 2e-27 | 122 | 30 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 440 | O96017 | 543 | CHK2_HUMAN Serine/threonine-protein kinase Ch... | 272 | 3e-27 | 121 | 33 | 50 | GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0044257; P:cellular protein catabolic process; IMP:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; IMP:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:UniProtKB.::GO:0006302; P:double-strand break repair; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0042176; P:regulation of protein catabolic process; IMP:UniProtKB.::GO:0090399; P:replicative senescence; NAS:BHF-UCL.::GO:0072428; P:signal transduction involved in intra-S DNA damage checkpoint; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 441 | Q6ZEZ5 | 585 | NEK3_ORYSJ Serine/threonine-protein kinase Ne... | 253 | 3e-27 | 121 | 28 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 442 | P0C8E4 | 606 | M3K7_RAT Mitogen-activated protein kinase kin... | 255 | 3e-27 | 122 | 30 | 54 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 443 | Q10SC8 | 456 | CIPK9_ORYSJ CBL-interacting protein kinase 9 ... | 265 | 3e-27 | 120 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 444 | Q8RXT4 | 555 | NEK4_ARATH Serine/threonine-protein kinase Ne... | 254 | 3e-27 | 121 | 28 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 445 | Q80XI6 | 850 | M3K11_MOUSE Mitogen-activated protein kinase ... | 298 | 3e-27 | 122 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 446 | Q62862 | 448 | MP2K5_RAT Dual specificity mitogen-activated ... | 267 | 3e-27 | 120 | 30 | 51 | GO:0005829; C:cytosol; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004708; F:MAP kinase kinase activity; IC:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0070375; P:ERK5 cascade; IMP:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; IMP:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IMP:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IMP:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; IMP:RGD.::GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:RGD.::GO:0051247; P:positive regulation of protein metabolic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL. | 447 | O96821 | 288 | CDC2H_PLAKH Cell division control protein 2 h... | 287 | 3e-27 | 117 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | | 448 | O43318 | 606 | M3K7_HUMAN Mitogen-activated protein kinase k... | 255 | 3e-27 | 121 | 30 | 54 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0007252; P:I-kappaB phosphorylation; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; IDA:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 449 | Q08942 | 431 | NRKA_TRYBB Putative serine/threonine-protein ... | 280 | 3e-27 | 119 | 30 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 450 | Q62101 | 918 | KPCD1_MOUSE Serine/threonine-protein kinase D... | 257 | 3e-27 | 123 | 28 | 54 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0048193; P:Golgi vesicle transport; IMP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:UniProtKB.::GO:0010837; P:regulation of keratinocyte proliferation; IMP:UniProtKB. | 451 | Q869W6 | 349 | MYLKG_DICDI Probable myosin light chain kinas... | 265 | 3e-27 | 119 | 28 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | GO:0007165; P:signal transduction; ISS:dictyBase. |