Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YAL058W
Length:
502
Number of sequences:
5887
Description:
YAL058W CNE1 SGDID:S000000054, Chr I from 37464-38972, Genome Release 64-1-1, Verified ORF, "Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P27797    417   CALR_HUMAN Calreticulin OS=Homo sapiens (Huma...3926e-31     127     28     43GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; TAS:Reactome.::GO:0042824; C:MHC class I peptide loading complex; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0030670; C:phagocytic vesicle membrane; TAS:Reactome.::GO:0005844; C:polysome; ISS:BHF-UCL.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IDA:BHF-UCL.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0030246; F:carbohydrate binding; TAS:BHF-UCL.::GO:0051087; F:chaperone binding; TAS:BHF-UCL.::GO:0001849; F:complement component C1q binding; TAS:BHF-UCL.::GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0005178; F:integrin binding; IPI:BHF-UCL.::GO:0003729; F:mRNA binding; IDA:BHF-UCL.::GO:0044183; F:protein binding involved in protein folding; TAS:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0051082; F:unfolded protein binding; TAS:BHF-UCL.::GO:0008270; F:zinc ion binding; TAS:BHF-UCL.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007050; P:cell cycle arrest; IGI:BHF-UCL.::GO:0090398; P:cellular senescence; IGI:BHF-UCL.::GO:0042921; P:glucocorticoid receptor signaling pathway; TAS:BHF-UCL.::GO:0033144; P:negative regulation of intracellular steroid hormone receptor signaling pathway; IDA:BHF-UCL.::GO:0045665; P:negative regulation of neuron differentiation; IDA:BHF-UCL.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0017148; P:negative regulation of translation; ISS:BHF-UCL.::GO:0002502; P:peptide antigen assembly with MHC class I protein complex; ISS:BHF-UCL.::GO:0045787; P:positive regulation of cell cycle; IGI:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.::GO:0045740; P:positive regulation of DNA replication; IGI:BHF-UCL.::GO:0050766; P:positive regulation of phagocytosis; ISS:BHF-UCL.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006611; P:protein export from nucleus; IDA:UniProtKB.::GO:0034504; P:protein localization to nucleus; IDA:UniProtKB.::GO:0022417; P:protein maturation by protein folding; TAS:BHF-UCL.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0051208; P:sequestering of calcium ion; TAS:BHF-UCL.
32P28491    417   CALR_PIG Calreticulin OS=Sus scrofa (Pig). GN...3611e-30     126     28     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0050821; P:protein stabilization; ISS:UniProtKB.
33O81919    416   CALR_BETVU Calreticulin OS=Beta vulgaris (Sug...4062e-30     125     28     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
34Q61KR9    396   CALR_CAEBR Calreticulin OS=Caenorhabditis bri...3885e-30     124     28     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
35P15253    418   CALR_RABIT Calreticulin OS=Oryctolagus cunicu...3837e-30     124     27     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0050821; P:protein stabilization; ISS:UniProtKB.
36P29413    406   CALR_DROME Calreticulin OS=Drosophila melanog...3817e-30     124     27     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:FlyBase.::GO:0045169; C:fusome; IDA:FlyBase.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0048854; P:brain morphogenesis; IMP:FlyBase.::GO:0031987; P:locomotion involved in locomotory behavior; IMP:FlyBase.::GO:0042048; P:olfactory behavior; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; TAS:FlyBase.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0001964; P:startle response; IMP:FlyBase.
37Q23858    424   CALR_DICDI Calreticulin OS=Dictyostelium disc...3657e-29     121     28     43GO:0005813; C:centrosome; IDA:dictyBase.::GO:0005788; C:endoplasmic reticulum lumen; TAS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005509; F:calcium ion binding; TAS:dictyBase.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006911; P:phagocytosis, engulfment; IGI:dictyBase.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0051707; P:response to other organism; TAS:dictyBase.
38P27798    395   CALR_CAEEL Calreticulin OS=Caenorhabditis ele...3887e-29     120     28     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IDA:WormBase.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0030421; P:defecation; IGI:WormBase.::GO:0031581; P:hemidesmosome assembly; IGI:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0048609; P:multicellular organismal reproductive process; IGI:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0012501; P:programmed cell death; IGI:WormBase.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IMP:WormBase.
39Q9SP22    420   CALR_MAIZE Calreticulin OS=Zea mays (Maize). ...4098e-29     121     28     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
40Q9ZPP1    416   CALR_BERST Calreticulin OS=Berberis stolonife...4015e-28     119     28     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
41P93508    415   CALR_RICCO Calreticulin OS=Ricinus communis (...3796e-28     119     28     43GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
42Q9ZNY3    401   CALR_EUGGR Calreticulin OS=Euglena gracilis. ...4156e-28     118     28     45GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
43Q9XF98    421   CALR_PRUAR Calreticulin OS=Prunus armeniaca (...3922e-27     117     28     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
44Q7Z1E6    398   CALR_BOMMO Calreticulin OS=Bombyx mori (Silk ...3755e-27     115     26     41GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
45Q38858    424   CALR2_ARATH Calreticulin-2 OS=Arabidopsis tha...4211e-25     112     27     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0006979; P:response to oxidative stress; IDA:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
46O04151    425   CALR1_ARATH Calreticulin-1 OS=Arabidopsis tha...4287e-24     107     25     41GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0055074; P:calcium ion homeostasis; IGI:TAIR.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
47Q06814    393   CALR_SCHMA Calreticulin OS=Schistosoma manson...3248e-18     89     28     44GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
48Q96L12    384   CALR3_HUMAN Calreticulin-3 OS=Homo sapiens (H...4040.00000000002     69.3     23     37GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
49Q2TBR8    384   CALR3_BOVIN Calreticulin-3 OS=Bos taurus (Bov...3640.0000000002     65.9     22     38GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
50Q9D9Q6    380   CALR3_MOUSE Calreticulin-3 OS=Mus musculus (M...3680.00000001     60.5     21     37GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
51Q8TAD4    765   ZNT5_HUMAN Zinc transporter 5 OS=Homo sapiens...920.9     35.8     26     46GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:UniProtKB.::GO:0005624; C:membrane fraction; NAS:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0030667; C:secretory granule membrane; TAS:Reactome.
GO:0008270; F:zinc ion binding; NAS:UniProtKB.::GO:0005385; F:zinc ion transmembrane transporter activity; IDA:UniProtKB.
GO:0006882; P:cellular zinc ion homeostasis; IDA:UniProtKB.::GO:0006824; P:cobalt ion transport; IDA:MGI.::GO:0010155; P:regulation of proton transport; NAS:UniProtKB.::GO:0010043; P:response to zinc ion; IDA:UniProtKB.
52Q318P8    1128   IF2_PROM9 Translation initiation factor IF-2 ...1632.6     34.7     26     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
53Q9QZ23    255   NFU1_MOUSE NFU1 iron-sulfur cluster scaffold ...794     33.5     38     48GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.
54Q8TET4    914   GANC_HUMAN Neutral alpha-glucosidase C OS=Hom...757.3     33.1     32     51
GO:0030246; F:carbohydrate binding; IEA:InterPro.::GO:0032450; F:maltose alpha-glucosidase activity; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
55Q8R4H9    761   ZNT5_MOUSE Zinc transporter 5 OS=Mus musculus...928.5     32.7     25     45GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
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