rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q04121 | 633 | NHX1_YEAST Endosomal/prevacuolar sodium/hydro... | 633 | 0 | 1284 | 99 | 99 | GO:0005769; C:early endosome; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:SGD. | | | | | | | | | | GO:0015386; F:potassium:hydrogen antiporter activity; IMP:SGD.::GO:0015385; F:sodium:hydrogen antiporter activity; IMP:SGD. | | | | | | | | | | GO:0007035; P:vacuolar acidification; IMP:SGD. | 2 | O13726 | 567 | YDO6_SCHPO Uncharacterized Na(+)/H(+) antipor... | 573 | 0 | 556 | 53 | 72 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; ISS:PomBase. | | | | | | | | | | GO:0015386; F:potassium:hydrogen antiporter activity; ISS:PomBase.::GO:0015385; F:sodium:hydrogen antiporter activity; ISS:PomBase. | | | | | | | | | | GO:0006885; P:regulation of pH; ISS:PomBase. | 3 | Q92581 | 669 | SL9A6_HUMAN Sodium/hydrogen exchanger 6 OS=Ho... | 444 | 5e-82 | 278 | 38 | 57 | GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; TAS:ProtInc. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 4 | Q8BZ00 | 644 | SL9A9_MOUSE Sodium/hydrogen exchanger 9 OS=Mu... | 504 | 8e-82 | 276 | 35 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 5 | Q8IVB4 | 645 | SL9A9_HUMAN Sodium/hydrogen exchanger 9 OS=Ho... | 497 | 2e-80 | 273 | 34 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; TAS:Reactome.::GO:0055037; C:recycling endosome; IDA:UniProtKB. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 6 | Q8BLV3 | 726 | SL9A7_MOUSE Sodium/hydrogen exchanger 7 OS=Mu... | 484 | 5e-80 | 274 | 34 | 54 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0015386; F:potassium:hydrogen antiporter activity; ISS:UniProtKB.::GO:0015385; F:sodium:hydrogen antiporter activity; ISS:UniProtKB. | | | | | | | | | | GO:0006885; P:regulation of pH; ISS:UniProtKB. | 7 | Q96T83 | 725 | SL9A7_HUMAN Sodium/hydrogen exchanger 7 OS=Ho... | 484 | 9e-77 | 265 | 34 | 53 | GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0015386; F:potassium:hydrogen antiporter activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.::GO:0015385; F:sodium:hydrogen antiporter activity; IDA:UniProtKB. | | | | | | | | | | GO:0006885; P:regulation of pH; IDA:UniProtKB. | 8 | Q552S0 | 674 | NHE1_DICDI Sodium/hydrogen exchanger 1 OS=Dic... | 462 | 6e-64 | 228 | 32 | 56 | GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0016021; C:integral to membrane; ISS:dictyBase.::GO:0031256; C:leading edge membrane; IDA:dictyBase. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; ISS:dictyBase. | | | | | | | | | | GO:0097230; P:cell motility in response to potassium ion; IMP:dictyBase.::GO:0036051; P:protein localization to trailing edge; IMP:dictyBase.::GO:0051453; P:regulation of intracellular pH; IMP:dictyBase. | 9 | Q8R4D1 | 576 | SL9A8_MOUSE Sodium/hydrogen exchanger 8 OS=Mu... | 461 | 9e-61 | 218 | 32 | 54 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015386; F:potassium:hydrogen antiporter activity; IDA:MGI.::GO:0015385; F:sodium:hydrogen antiporter activity; IDA:MGI. | | | | | | | | | | GO:0051453; P:regulation of intracellular pH; IDA:MGI. | 10 | Q4L208 | 575 | SL9A8_RAT Sodium/hydrogen exchanger 8 OS=Ratt... | 461 | 2e-60 | 217 | 32 | 54 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 11 | Q8RWU6 | 535 | NHX6_ARATH Sodium/hydrogen exchanger 6 OS=Ara... | 513 | 2e-60 | 216 | 30 | 49 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 12 | Q5ZJ75 | 574 | SL9A8_CHICK Sodium/hydrogen exchanger 8 OS=Ga... | 461 | 5e-60 | 216 | 31 | 54 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 13 | Q9Y2E8 | 581 | SL9A8_HUMAN Sodium/hydrogen exchanger 8 OS=Ho... | 461 | 8e-60 | 215 | 32 | 54 | GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 14 | Q8S397 | 529 | NHX4_ARATH Sodium/hydrogen exchanger 4 OS=Ara... | 417 | 4e-54 | 198 | 32 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IDA:TAIR. | | | | | | | | | | GO:0055075; P:potassium ion homeostasis; IMP:TAIR.::GO:0006885; P:regulation of pH; IEA:InterPro. | 15 | Q8S396 | 521 | NHX5_ARATH Sodium/hydrogen exchanger 5 OS=Ara... | 457 | 1e-51 | 191 | 33 | 52 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0010351; P:lithium ion transport; IGI:TAIR.::GO:0006885; P:regulation of pH; IEA:InterPro. | 16 | Q84WG1 | 503 | NHX3_ARATH Sodium/hydrogen exchanger 3 OS=Ara... | 448 | 7e-50 | 186 | 30 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro.::GO:0009651; P:response to salt stress; IMP:TAIR. | 17 | Q56XP4 | 546 | NHX2_ARATH Sodium/hydrogen exchanger 2 OS=Ara... | 471 | 2e-47 | 179 | 30 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 18 | Q68KI4 | 538 | NHX1_ARATH Sodium/hydrogen exchanger 1 OS=Ara... | 470 | 8e-47 | 177 | 30 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000325; C:plant-type vacuole; TAS:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0015385; F:sodium:hydrogen antiporter activity; IDA:TAIR. | | | | | | | | | | GO:0048366; P:leaf development; IMP:TAIR.::GO:0010351; P:lithium ion transport; IGI:TAIR.::GO:0006885; P:regulation of pH; IEA:InterPro.::GO:0009651; P:response to salt stress; IMP:TAIR. | 19 | P48763 | 813 | SL9A2_RAT Sodium/hydrogen exchanger 2 OS=Ratt... | 443 | 2e-45 | 176 | 30 | 51 | GO:0016324; C:apical plasma membrane; TAS:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IDA:RGD. | | | | | | | | | | | 20 | P50482 | 809 | SL9A2_RABIT Sodium/hydrogen exchanger 2 OS=Or... | 443 | 2e-44 | 173 | 29 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 21 | Q4R8V4 | 542 | SL9A8_MACFA Sodium/hydrogen exchanger 8 OS=Ma... | 461 | 7e-44 | 169 | 29 | 48 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 22 | Q9UBY0 | 812 | SL9A2_HUMAN Sodium/hydrogen exchanger 2 OS=Ho... | 443 | 9e-44 | 171 | 30 | 50 | GO:0016021; C:integral to membrane; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; TAS:ProtInc. | | | | | | | | | | | 23 | Q01345 | 759 | NHEB_ONCMY Na(+)/H(+) exchanger beta OS=Oncor... | 429 | 2e-42 | 166 | 28 | 50 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 24 | P48764 | 834 | SL9A3_HUMAN Sodium/hydrogen exchanger 3 OS=Ho... | 385 | 1e-40 | 162 | 30 | 51 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; ISS:UniProtKB. | | | | | | | | | | | 25 | P26433 | 831 | SL9A3_RAT Sodium/hydrogen exchanger 3 OS=Ratt... | 385 | 2e-40 | 162 | 31 | 51 | GO:0031526; C:brush border membrane; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0015385; F:sodium:hydrogen antiporter activity; IDA:RGD. | | | | | | | | | | GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0006898; P:receptor-mediated endocytosis; IMP:RGD.::GO:0006885; P:regulation of pH; IDA:RGD.::GO:0002028; P:regulation of sodium ion transport; IMP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD. | 26 | P26432 | 832 | SL9A3_RABIT Sodium/hydrogen exchanger 3 OS=Or... | 379 | 3e-40 | 160 | 30 | 52 | GO:0005903; C:brush border; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015385; F:sodium:hydrogen antiporter activity; IDA:UniProtKB. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 27 | Q61165 | 820 | SL9A1_MOUSE Sodium/hydrogen exchanger 1 OS=Mu... | 453 | 8e-39 | 156 | 30 | 51 | GO:0016323; C:basolateral plasma membrane; TAS:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0015385; F:sodium:hydrogen antiporter activity; IDA:MGI. | | | | | | | | | | GO:0006885; P:regulation of pH; IDA:MGI.::GO:0001101; P:response to acid; IMP:MGI.::GO:0010447; P:response to acidity; IMP:MGI. | 28 | P26431 | 820 | SL9A1_RAT Sodium/hydrogen exchanger 1 OS=Ratt... | 453 | 1e-38 | 156 | 30 | 51 | GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; IDA:RGD. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0015385; F:sodium:hydrogen antiporter activity; IMP:RGD.::GO:0008134; F:transcription factor binding; IDA:RGD. | | | | | | | | | | GO:0030154; P:cell differentiation; IEP:RGD.::GO:0016049; P:cell growth; IEP:RGD.::GO:0007243; P:intracellular protein kinase cascade; IMP:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0006885; P:regulation of pH; TAS:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD. | 29 | Q28362 | 839 | SL9A3_DIDMA Sodium/hydrogen exchanger 3 OS=Di... | 385 | 2e-38 | 155 | 31 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 30 | P26434 | 717 | SL9A4_RAT Sodium/hydrogen exchanger 4 OS=Ratt... | 451 | 2e-38 | 154 | 29 | 50 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. | | | | | | | | | | GO:0006885; P:regulation of pH; IEA:InterPro. | 31 | P19634 | 815 | SL9A1_HUMAN Sodium/hydrogen exchanger 1 OS=Ho... | 454 | 6e-38 | 154 | 30 | 52 | GO:0016021; C:integral to membrane; TAS:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006885; P:regulation of pH; TAS:UniProtKB. |