rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | O14578 | 2027 | CTRO_HUMAN Citron Rho-interacting kinase OS=H... | 298 | 1e-38 | 159 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0033205; P:cell cycle cytokinesis; IMP:UniProtKB.::GO:0048699; P:generation of neurons; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007067; P:mitosis; ISS:UniProtKB. | 182 | Q4R4U2 | 697 | KPCG_MACFA Protein kinase C gamma type OS=Mac... | 289 | 1e-38 | 156 | 34 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 183 | O13310 | 469 | ORB6_SCHPO Serine/threonine-protein kinase or... | 316 | 1e-38 | 154 | 28 | 52 | GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0000078; P:cell shape checkpoint; NAS:PomBase.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:2000100; P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase. | 184 | P49025 | 2055 | CTRO_MOUSE Citron Rho-interacting kinase OS=M... | 239 | 1e-38 | 159 | 35 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0048699; P:generation of neurons; IDA:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007067; P:mitosis; IDA:UniProtKB. | 185 | P05128 | 682 | KPCG_BOVIN Protein kinase C gamma type OS=Bos... | 299 | 1e-38 | 156 | 33 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 186 | P31749 | 480 | AKT1_HUMAN RAC-alpha serine/threonine-protein... | 294 | 1e-38 | 153 | 32 | 52 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0030235; F:nitric-oxide synthase regulator activity; IMP:BHF-UCL.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0006924; P:activation-induced cell death of T cells; IMP:MGI.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; TAS:UniProtKB.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0031999; P:negative regulation of fatty acid beta-oxidation; IMP:BHF-UCL.::GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.::GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0031659; P:positive regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.::GO:2001047; P:regulation of G1/S transition checkpoint; TAS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0034405; P:response to fluid shear stress; IMP:BHF-UCL.::GO:0009408; P:response to heat; TAS:ProtInc.::GO:0070141; P:response to UV-A; IDA:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 187 | P11792 | 824 | SCH9_YEAST Serine/threonine-protein kinase SC... | 291 | 2e-38 | 157 | 32 | 54 | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IGI:SGD. | | | | | | | | | | GO:0001324; P:age-dependent response to oxidative stress involved in chronological cell aging; IMP:SGD.::GO:0060963; P:positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0047484; P:regulation of response to osmotic stress; IMP:SGD.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD. | 188 | Q7TSJ6 | 1042 | LATS2_MOUSE Serine/threonine-protein kinase L... | 314 | 2e-38 | 157 | 34 | 51 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0009755; P:hormone-mediated signaling pathway; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0046620; P:regulation of organ growth; IMP:MGI. | 189 | P32328 | 564 | DBF20_YEAST Serine/threonine-protein kinase D... | 333 | 2e-38 | 154 | 31 | 50 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0007049; P:cell cycle; IEP:SGD. | 190 | P70336 | 1388 | ROCK2_MOUSE Rho-associated protein kinase 2 O... | 300 | 2e-38 | 158 | 32 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031616; C:spindle pole centrosome; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000910; P:cytokinesis; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0010825; P:positive regulation of centrosome duplication; IMP:MGI. | 191 | Q9UK32 | 745 | KS6A6_HUMAN Ribosomal protein S6 kinase alpha... | 275 | 2e-20 | 100 | 29 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045992; P:negative regulation of embryonic development; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:2000381; P:negative regulation of mesoderm development; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 192 | P87253 | 1142 | KPC1_NEUCR Protein kinase C-like OS=1257 / FG... | 308 | 2e-38 | 157 | 30 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 193 | P38991 | 367 | IPL1_YEAST Spindle assembly checkpoint kinase... | 272 | 2e-38 | 150 | 33 | 53 | GO:0032133; C:chromosome passenger complex; IDA:SGD.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005828; C:kinetochore microtubule; IDA:SGD.::GO:0051233; C:spindle midzone; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:SGD.::GO:0045143; P:homologous chromosome segregation; IMP:SGD.::GO:0045144; P:meiotic sister chromatid segregation; IMP:SGD.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0051228; P:mitotic spindle disassembly; IMP:SGD.::GO:0032465; P:regulation of cytokinesis; IMP:SGD.::GO:0031577; P:spindle checkpoint; IMP:SGD. | 194 | Q16974 | 649 | KPC1_APLCA Calcium-dependent protein kinase C... | 289 | 3e-38 | 155 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 195 | P40376 | 512 | KAPB_SCHPO cAMP-dependent protein kinase cata... | 306 | 3e-38 | 153 | 31 | 54 | GO:0005952; C:cAMP-dependent protein kinase complex; TAS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IGI:PomBase.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0001315; P:age-dependent response to reactive oxygen species; IMP:PomBase.::GO:0019933; P:cAMP-mediated signaling; IC:PomBase.::GO:0001300; P:chronological cell aging; IGI:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; IMP:PomBase.::GO:0031138; P:negative regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0006110; P:regulation of glycolysis; NAS:PomBase. | 196 | Q9NRM7 | 1088 | LATS2_HUMAN Serine/threonine-protein kinase L... | 309 | 3e-38 | 157 | 33 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0000922; C:spindle pole; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0035329; P:hippo signaling cascade; IDA:BHF-UCL.::GO:0009755; P:hormone-mediated signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB. | 197 | P38070 | 525 | YPK3_YEAST AGC kinase YPK3 OS=Saccharomyces c... | 307 | 3e-38 | 153 | 32 | 50 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 198 | Q1ZXI5 | 1350 | Y1558_DICDI Probable serine/threonine-protein... | 361 | 3e-38 | 157 | 29 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 199 | P36583 | 1016 | PCK2_SCHPO Protein kinase C-like 2 OS=Schizos... | 306 | 3e-38 | 157 | 31 | 52 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005622; C:intracellular; IC:GOC. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004697; F:protein kinase C activity; TAS:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0035556; P:intracellular signal transduction; IC:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0032949; P:regulation of alpha-glucan biosynthetic process; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase. | 200 | P53683 | 533 | CDPK2_ORYSJ Calcium-dependent protein kinase ... | 271 | 3e-38 | 153 | 33 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 201 | O19111 | 591 | KPCZ_RABIT Protein kinase C zeta type OS=Oryc... | 313 | 4e-38 | 154 | 30 | 51 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:UniProtKB.::GO:0046628; P:positive regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:2001181; P:positive regulation of interleukin-10 secretion; ISS:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:2000553; P:positive regulation of T-helper 2 cell cytokine production; ISS:UniProtKB.::GO:0045630; P:positive regulation of T-helper 2 cell differentiation; ISS:UniProtKB. | 202 | Q25378 | 658 | KPC1_LYTPI Protein kinase C OS=Lytechinus pic... | 298 | 4e-38 | 154 | 31 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 203 | Q13237 | 762 | KGP2_HUMAN cGMP-dependent protein kinase 2 OS... | 307 | 4e-38 | 155 | 30 | 53 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 204 | P36582 | 988 | PCK1_SCHPO Protein kinase C-like 1 OS=Schizos... | 293 | 4e-38 | 156 | 31 | 52 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004697; F:protein kinase C activity; TAS:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase. | 205 | Q64595 | 762 | KGP2_RAT cGMP-dependent protein kinase 2 OS=R... | 307 | 4e-38 | 155 | 30 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 206 | O59790 | 355 | ARK1_SCHPO Serine/threonine-protein kinase ar... | 268 | 4e-38 | 150 | 31 | 53 | GO:0032133; C:chromosome passenger complex; NAS:PomBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0051233; C:spindle midzone; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0051315; P:attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; TAS:PomBase.::GO:0033205; P:cell cycle cytokinesis; IMP:PomBase.::GO:2000775; P:histone H3-S10 phosphorylation involved in chromosome condensation; IDA:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0034501; P:protein localization to kinetochore; IGI:PomBase.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IGI:PomBase.::GO:0031134; P:sister chromatid biorientation; TAS:PomBase. | 207 | P09216 | 737 | KPCE_RAT Protein kinase C epsilon type OS=Rat... | 285 | 4e-38 | 155 | 30 | 52 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:RGD.::GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0010763; P:positive regulation of fibroblast migration; ISS:UniProtKB.::GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.::GO:0035669; P:TRAM-dependent toll-like receptor 4 signaling pathway; ISS:UniProtKB. | 208 | P97477 | 395 | AURKA_MOUSE Aurora kinase A OS=Mus musculus (... | 267 | 4e-38 | 150 | 29 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 209 | P13678 | 634 | KPC3_DROME Protein kinase C OS=Drosophila mel... | 303 | 4e-38 | 154 | 31 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034389; P:lipid particle organization; IMP:FlyBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0045471; P:response to ethanol; IDA:FlyBase. | 210 | Q00078 | 1096 | KPC1_ASPNG Protein kinase C-like OS=Aspergill... | 288 | 5e-38 | 156 | 30 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 211 | Q2L6W9 | 476 | SAX1_CAEEL Serine/threonine-protein kinase sa... | 269 | 5e-38 | 152 | 31 | 54 | GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:WormBase. | | | | | | | | | | GO:0030031; P:cell projection assembly; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:WormBase.::GO:0030308; P:negative regulation of cell growth; IMP:WormBase.::GO:0031175; P:neuron projection development; IMP:WormBase.::GO:0008360; P:regulation of cell shape; IMP:WormBase. |