| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q9Z0U1 | 1167 | ZO2_MOUSE Tight junction protein ZO-2 OS=Mus ... | 29 | 0.7 | 37.7 | 52 | 72 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 122 | Q9UDY2 | 1190 | ZO2_HUMAN Tight junction protein ZO-2 OS=Homo... | 29 | 0.73 | 37.4 | 52 | 72 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004385; F:guanylate kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0035329; P:hippo signaling cascade; TAS:Reactome. | 123 | B6YWG5 | 87 | Y940_THEON UPF0248 protein TON_0940 OS=Thermo... | 85 | 0.8 | 34.7 | 24 | 51 | | | | | | | | | | | | | | | | | | | | | | 124 | P39521 | 936 | FHL1_YEAST Pre-rRNA-processing protein FHL1 O... | 99 | 1 | 37 | 33 | 43 | GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0070491; F:repressing transcription factor binding; IPI:SGD.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD. | | | | | | | | | | GO:0010688; P:negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter; IMP:SGD.::GO:0060963; P:positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter; IMP:SGD.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome. | 125 | Q92C36 | 420 | Y1355_LISIN Putative zinc metalloprotease Lin... | 59 | 1.1 | 36.6 | 32 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 126 | Q49WF1 | 597 | HTRAL_STAS1 Serine protease htrA-like OS=DSM ... | 199 | 1.6 | 36.2 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 127 | Q8YHH1 | 379 | Y829_BRUME Putative zinc metalloprotease BMEI... | 60 | 1.9 | 35.8 | 32 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 128 | Q8G0E1 | 379 | Y1156_BRUSU Putative zinc metalloprotease BR1... | 60 | 2 | 35.8 | 32 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 129 | O83609 | 450 | Y600_TREPA Putative zinc metalloprotease TP_0... | 48 | 2.1 | 35.8 | 33 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 130 | Q8NI35 | 1801 | INADL_HUMAN InaD-like protein OS=Homo sapiens... | 205 | 2.4 | 35.8 | 24 | 40 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0070830; P:tight junction assembly; TAS:Reactome. | 131 | Q96RT1 | 1412 | LAP2_HUMAN Protein LAP2 OS=Homo sapiens (Huma... | 164 | 3 | 35.4 | 26 | 40 | GO:0005604; C:basement membrane; TAS:ProtInc.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0030056; C:hemidesmosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005176; F:ErbB-2 class receptor binding; TAS:UniProtKB.::GO:0005178; F:integrin binding; IPI:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB. | | | | | | | | | | GO:0045175; P:basal protein localization; NAS:UniProtKB.::GO:0007155; P:cell adhesion; NAS:UniProtKB.::GO:0007049; P:cell cycle; NAS:UniProtKB.::GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0045104; P:intermediate filament cytoskeleton organization; NAS:UniProtKB. | 132 | Q80TH2 | 1402 | LAP2_MOUSE Protein LAP2 OS=Mus musculus (Mous... | 85 | 3.7 | 35.4 | 32 | 47 | GO:0030056; C:hemidesmosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006605; P:protein targeting; IDA:MGI. | 133 | Q12923 | 2485 | PTN13_HUMAN Tyrosine-protein phosphatase non-... | 59 | 3.9 | 35 | 31 | 54 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | | 134 | Q9FL12 | 592 | DEGP9_ARATH Protease Do-like 9 OS=Arabidopsis... | 329 | 4.7 | 34.7 | 23 | 41 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 135 | Q9WVQ1 | 1275 | MAGI2_MOUSE Membrane-associated guanylate kin... | 68 | 6.4 | 34.7 | 34 | 54 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IPI:MGI.::GO:0046332; F:SMAD binding; IPI:UniProtKB.::GO:0070699; F:type II activin receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB. | 136 | O88382 | 1277 | MAGI2_RAT Membrane-associated guanylate kinas... | 68 | 6.5 | 34.3 | 34 | 54 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0036057; C:slit diaphragm; IDA:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0003094; P:glomerular filtration; IC:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; IDA:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0043113; P:receptor clustering; IDA:RGD.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB. | 137 | O15018 | 2839 | PDZD2_HUMAN PDZ domain-containing protein 2 O... | 48 | 7.2 | 34.3 | 38 | 56 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005576; C:extracellular region; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 138 | O97758 | 1769 | ZO1_CANFA Tight junction protein ZO-1 OS=Cani... | 71 | 7.7 | 34.3 | 31 | 51 | GO:0009986; C:cell surface; IDA:MGI.::GO:0031410; C:cytoplasmic vesicle; IDA:UniProtKB.::GO:0005921; C:gap junction; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0070830; P:tight junction assembly; IDA:UniProtKB. | 139 | Q9QZR8 | 2766 | PDZD2_RAT PDZ domain-containing protein 2 OS=... | 48 | 8.2 | 34.3 | 38 | 56 | GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005576; C:extracellular region; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; TAS:RGD. | 140 | A7UA95 | 1124 | RADIL_DANRE Ras-associating and dilute domain... | 62 | 8.4 | 33.9 | 34 | 65 | | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 141 | P39447 | 1745 | ZO1_MOUSE Tight junction protein ZO-1 OS=Mus ... | 71 | 8.5 | 34.3 | 31 | 51 | GO:0005913; C:cell-cell adherens junction; IDA:MGI.::GO:0005921; C:gap junction; IEA:UniProtKB-SubCell.::GO:0031674; C:I band; IEA:UniProtKB-SubCell.::GO:0046581; C:intercellular canaliculus; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:MGI. | | | | | | | | | | GO:0001825; P:blastocyst formation; IMP:MGI. | 142 | O95049 | 933 | ZO3_HUMAN Tight junction protein ZO-3 OS=Homo... | 38 | 8.5 | 33.9 | 37 | 63 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 143 | Q07157 | 1748 | ZO1_HUMAN Tight junction protein ZO-1 OS=Homo... | 71 | 8.6 | 34.3 | 31 | 51 | GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0005913; C:cell-cell adherens junction; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005921; C:gap junction; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007043; P:cell-cell junction assembly; TAS:ProtInc.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0035329; P:hippo signaling cascade; TAS:Reactome. | 144 | Q86UL8 | 1455 | MAGI2_HUMAN Membrane-associated guanylate kin... | 68 | 9 | 33.9 | 34 | 54 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; IPI:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; IDA:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0003402; P:planar cell polarity pathway involved in axis elongation; NAS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB. |
