rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
571 | Q8TC12 | 318 | RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo ... | 210 | 0.044 | 38.9 | 24 | 39 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:Reactome. | 572 | P07161 | 254 | ADH1_DROMU Alcohol dehydrogenase 1 OS=Drosoph... | 243 | 0.048 | 38.5 | 26 | 43 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 573 | Q05470 | 4538 | PKSL_BACSU Polyketide synthase PksL OS=Bacill... | 186 | 0.048 | 39.3 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 574 | O14351 | 247 | YB45_SCHPO Uncharacterized oxidoreductase C30... | 195 | 0.061 | 38.1 | 27 | 42 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; ISS:PomBase. | | | | | | | | | | GO:0006729; P:tetrahydrobiopterin biosynthetic process; ISS:PomBase. | 575 | Q8WUS8 | 393 | D42E1_HUMAN Short-chain dehydrogenase/reducta... | 94 | 0.065 | 38.5 | 30 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:InterPro. | 576 | P40580 | 263 | BZRD_YEAST Benzil reductase ((S)-benzoin form... | 196 | 0.069 | 37.7 | 25 | 42 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | | 577 | O75828 | 277 | CBR3_HUMAN Carbonyl reductase [NADPH] 3 OS=Ho... | 138 | 0.071 | 38.1 | 28 | 46 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB. | | | | | | | | | | | 578 | Q6CE86 | 372 | TSC10_YARLI 3-ketodihydrosphingosine reductas... | 210 | 0.071 | 38.1 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 579 | P47727 | 277 | CBR1_RAT Carbonyl reductase [NADPH] 1 OS=Ratt... | 256 | 0.071 | 37.7 | 23 | 38 | GO:0005829; C:cytosol; TAS:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005902; C:microvillus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0001542; P:ovulation from ovarian follicle; IEP:RGD.::GO:0018205; P:peptidyl-lysine modification; NAS:RGD.::GO:0042376; P:phylloquinone catabolic process; IDA:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. | 580 | P66784 | 254 | Y3820_MYCBO Uncharacterized oxidoreductase Mb... | 89 | 0.075 | 37.7 | 30 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 581 | P66783 | 254 | DPRE2_MYCTU Probable decaprenylphosphoryl-D-2... | 89 | 0.075 | 37.7 | 30 | 45 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035884; P:arabinan biosynthetic process; IDA:MTBBASE.::GO:0070592; P:cell wall polysaccharide biosynthetic process; IDA:MTBBASE.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0040007; P:growth; IMP:MTBBASE. | 582 | A4IGM4 | 286 | DHI1L_XENTR Hydroxysteroid 11-beta-dehydrogen... | 249 | 0.083 | 37.7 | 22 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 583 | Q64591 | 335 | DECR_RAT 2,4-dienoyl-CoA reductase, mitochond... | 197 | 0.085 | 37.7 | 24 | 45 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; TAS:RGD. | | | | | | | | | | | 584 | Q3SZD7 | 277 | CBR1_BOVIN Carbonyl reductase [NADPH] 1 OS=Bo... | 261 | 0.097 | 37.4 | 24 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 585 | Q6GI75 | 256 | FABI_STAAR Enoyl-[acyl-carrier-protein] reduc... | 161 | 0.1 | 37.4 | 25 | 43 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0050661; F:NADP binding; IDA:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.] | 586 | Q6PUF4 | 287 | DHI1L_CHICK Hydroxysteroid 11-beta-dehydrogen... | 214 | 0.1 | 37.4 | 22 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 587 | Q92247 | 412 | BLI4_NEUCR Putative oxidoreductase bli-4, mit... | 176 | 0.12 | 37.7 | 23 | 41 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 588 | O32099 | 243 | BZRD_BACSU Benzil reductase ((S)-benzoin form... | 165 | 0.13 | 37 | 26 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | | 589 | P28845 | 292 | DHI1_HUMAN Corticosteroid 11-beta-dehydrogena... | 173 | 0.14 | 37 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.] | 590 | Q99L04 | 313 | DHRS1_MOUSE Dehydrogenase/reductase SDR famil... | 205 | 0.16 | 37 | 26 | 41 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 591 | P16960 | 5035 | RYR1_PIG Ryanodine receptor 1 OS=Sus scrofa (... | 81 | 0.17 | 37.4 | 31 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033017; C:sarcoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0006936; P:muscle contraction; ISS:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:UniProtKB.::GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.::GO:0043588; P:skin development; ISS:UniProtKB. | 592 | Q6P7R8 | 312 | DHB12_RAT Estradiol 17-beta-dehydrogenase 12 ... | 182 | 0.19 | 36.6 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 593 | Q9CQ62 | 335 | DECR_MOUSE 2,4-dienoyl-CoA reductase, mitocho... | 200 | 0.19 | 36.6 | 26 | 42 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IEA:EC. | | | | | | | | | | | 594 | P50172 | 292 | DHI1_MOUSE Corticosteroid 11-beta-dehydrogena... | 183 | 0.21 | 36.6 | 22 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030324; P:lung development; IMP:MGI.::GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 595 | O70503 | 312 | DHB12_MOUSE Estradiol 17-beta-dehydrogenase 1... | 182 | 0.26 | 36.2 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031012; C:extracellular matrix; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005518; F:collagen binding; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0001968; F:fibronectin binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030198; P:extracellular matrix organization; IDA:MGI.::GO:0010811; P:positive regulation of cell-substrate adhesion; IDA:MGI.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 596 | E9PZQ0 | 5035 | RYR1_MOUSE Ryanodine receptor 1 OS=Mus muscul... | 81 | 0.28 | 37 | 32 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030314; C:junctional membrane complex; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0033017; C:sarcoplasmic reticulum membrane; IDA:UniProtKB.::GO:0030315; C:T-tubule; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0002020; F:protease binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IMP:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; IMP:UniProtKB.::GO:0006936; P:muscle contraction; IMP:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; IMP:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; IMP:UniProtKB.::GO:0006937; P:regulation of muscle contraction; TAS:MGI.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IMP:UniProtKB.::GO:0048741; P:skeletal muscle fiber development; IMP:UniProtKB.::GO:0043588; P:skin development; IMP:UniProtKB. | 597 | Q16698 | 335 | DECR_HUMAN 2,4-dienoyl-CoA reductase, mitocho... | 143 | 0.28 | 36.2 | 26 | 48 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB.::GO:0016651; F:oxidoreductase activity, acting on NADH or NADPH; TAS:Reactome. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB. | 598 | P11716 | 5037 | RYR1_RABIT Ryanodine receptor 1 OS=Oryctolagu... | 81 | 0.28 | 36.6 | 32 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033017; C:sarcoplasmic reticulum membrane; ISS:UniProtKB.::GO:0014802; C:terminal cisterna; IDA:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IDA:BHF-UCL.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0006936; P:muscle contraction; ISS:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:UniProtKB.::GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.::GO:0043588; P:skin development; ISS:UniProtKB. | 599 | P40872 | 4262 | PKSM_BACSU Polyketide synthase PksM OS=Bacill... | 139 | 0.3 | 36.6 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 600 | P37058 | 310 | DHB3_HUMAN Testosterone 17-beta-dehydrogenase... | 93 | 0.32 | 35.8 | 29 | 49 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; TAS:Reactome.::GO:0030539; P:male genitalia development; TAS:ProtInc. | 601 | P21817 | 5038 | RYR1_HUMAN Ryanodine receptor 1 OS=Homo sapie... | 81 | 0.37 | 36.6 | 32 | 49 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0031674; C:I band; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0014701; C:junctional sarcoplasmic reticulum membrane; TAS:BHF-UCL.::GO:0005790; C:smooth endoplasmic reticulum; TAS:ProtInc.::GO:0014802; C:terminal cisterna; ISS:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; ISS:BHF-UCL.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0006936; P:muscle contraction; ISS:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:BHF-UCL.::GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.::GO:0043588; P:skin development; ISS:UniProtKB. |